Síndrome metabólica e aterosclerose subclínica em adolescentes: Uma avaliação dos critérios diagnósticos
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da UEPB |
Texto Completo: | http://tede.bc.uepb.edu.br/tede/jspui/handle/tede/2785 |
Resumo: | Introduction: epidemiological evidence show strong links of the metabolic syndrome with subclinical atherosclerosis. Objective: to identify the best diagnosis of metabolic syndrome criteria to detect thickening of the intima-media complex of the carotid in adolescents. Methods: cross-sectional study with a quantitative approach, developed in 512 adolescents from public schools aged between 15 and 19 years between September 2012 and June 2013. For diagnosis of metabolic syndrome were used two criteria of the International Diabetes Federation and the NationalCholesterolEducationProgram / AdultTreatmentPanel III adapted by Cook. It was considered marked thickening of the average complex carotid intimal, when the value was equal to or greater than + 2Z. To evaluate the association between the criteria of the metabolic syndrome and thickening of the intimal average carotid complex we used the chi-square test was also evaluated the positive and negative preditivio value of each criterion to detect thickening. To verify the agreement of the two diagnostic criteria was used the Kappa test. We used SPSS version 22.0 and 95% confidence interval. Results: metabolic syndrome and systolic blood pressure changes identified by NationalCholesterolEducationProgram / AdultTreatment PanelIII adapted by COOK was associated with thickening of the intima-media complex-carotid (p = 0.020, p = 0.030, respectively). Metabolic syndrome was diagnosed by two criteria in 19.2% (<0.001) with low agreement, kappa of 0.28. The diagnostic criteria that had the highest positive predictive value was NationalCholesterolEducationProgram / AdultTreatmentPanel III adapted by COOK 15%. Conclusion: the NationalCholesterolEducationProgram / AdultTreatmentPanel III adapted by COOK was the criterion that was associated with the presence of thickening of the intima-media complex of the carotid. |
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Medeiros, Carla Campos Muniz64135667449http://lattes.cnpq.br/6730680514230870Coura, Alexsandro Silvahttp://lattes.cnpq.br/5597558131874152Vianna, Rodrigo Pinheiro de Toledohttp://lattes.cnpq.br/391505103508986108895315448http://lattes.cnpq.br/0956324322195962Oliveira, Renata Cardoso2017-07-20T12:18:56Z2016-03-23OLIVEIRA, R. C. Síndrome metabólica e aterosclerose subclínica em adolescentes: Uma avaliação dos critérios diagnósticos. 2016. 85f. Dissertação (Programa de Pós-Graduação em Saúde Pública - PPGSP) - Universidade Estadual da Paraíba, Campina Grande, 2016.http://tede.bc.uepb.edu.br/tede/jspui/handle/tede/2785Introduction: epidemiological evidence show strong links of the metabolic syndrome with subclinical atherosclerosis. Objective: to identify the best diagnosis of metabolic syndrome criteria to detect thickening of the intima-media complex of the carotid in adolescents. Methods: cross-sectional study with a quantitative approach, developed in 512 adolescents from public schools aged between 15 and 19 years between September 2012 and June 2013. For diagnosis of metabolic syndrome were used two criteria of the International Diabetes Federation and the NationalCholesterolEducationProgram / AdultTreatmentPanel III adapted by Cook. It was considered marked thickening of the average complex carotid intimal, when the value was equal to or greater than + 2Z. To evaluate the association between the criteria of the metabolic syndrome and thickening of the intimal average carotid complex we used the chi-square test was also evaluated the positive and negative preditivio value of each criterion to detect thickening. To verify the agreement of the two diagnostic criteria was used the Kappa test. We used SPSS version 22.0 and 95% confidence interval. Results: metabolic syndrome and systolic blood pressure changes identified by NationalCholesterolEducationProgram / AdultTreatment PanelIII adapted by COOK was associated with thickening of the intima-media complex-carotid (p = 0.020, p = 0.030, respectively). Metabolic syndrome was diagnosed by two criteria in 19.2% (<0.001) with low agreement, kappa of 0.28. The diagnostic criteria that had the highest positive predictive value was NationalCholesterolEducationProgram / AdultTreatmentPanel III adapted by COOK 15%. Conclusion: the NationalCholesterolEducationProgram / AdultTreatmentPanel III adapted by COOK was the criterion that was associated with the presence of thickening of the intima-media complex of the carotid.Introdução: evidências epidemiológicas apresentam fortes ligações da síndrome metabólica com a aterosclerose subclínica. Objetivo: identificar o melhor critério diagnóstico de síndrome metabólica para detecção do espessamento do complexo médio-intimal da carótida em adolescentes. Metodologia: estudo transversal, com abordagem quantitativa, desenvolvido em 512 adolescentes de escolas públicas com idade entre 15 e 19 anos no período de setembro de 2012 e junho de 2013. Para diagnóstico da síndrome metabólica foram utilizados dois critérios o do International Diabetes Federation e o NationalCholesterolEducationProgram/AdultTreatmentPanel III adaptado por COOK. Foi considerado espessamento acentuado do complexo médio intimal da carótida, quando o valor foi igual ou maior que + 2Z. Para avaliar a associação entre os critérios da síndrome metabólica e o espessamento do complexo médio intimal da carótida foi utilizado o teste do qui-quadrado, foi avaliado também o valor preditivio positivo e negativo de cada critério para detecção do espessamento. Para verificar a concordância dos dois critérios diagnósticos foi utilizado o teste de Kappa. Utilizou-se o SPSS versão 22.0 e intervalo de confiança de 95%. Resultados: a síndrome metabólica e a pressão arterial sistólica alterada identificada pelo NationalCholesterolEducationProgram/AdultTreatment PanelIII adaptado por COOK teve associação com o espessamento do complexo- médio-intimal da carótida (p= 0,020 , p= 0,030, respectivamente). A síndrome metabólica foi diagnosticada pelos dois critérios em 19,2% (<0,001) com baixa concordância, kappa de 0,28. O critério diagnóstico que apresentou maior valor preditivo positivo foi o NationalCholesterolEducationProgram/AdultTreatmentPanel III adaptado por COOK 15%. Conclusão: o NationalCholesterolEducationProgram/AdultTreatmentPanel III adaptado por COOK foi o critério que teve associação com a presença do espessamento do complexo médio-intimal da carótida.Submitted by Jean Medeiros (jeanletras@uepb.edu.br) on 2017-04-05T11:39:39Z No. of bitstreams: 1 PDF - Renata Cardoso Oliveira.pdf: 19968885 bytes, checksum: 15af104392b53c8bad1ec441601ddd44 (MD5)Approved for entry into archive by Secta BC (secta.csu.bc@uepb.edu.br) on 2017-07-20T12:18:56Z (GMT) No. of bitstreams: 1 PDF - Renata Cardoso Oliveira.pdf: 19968885 bytes, checksum: 15af104392b53c8bad1ec441601ddd44 (MD5)Made available in DSpace on 2017-07-20T12:18:56Z (GMT). No. of bitstreams: 1 PDF - Renata Cardoso Oliveira.pdf: 19968885 bytes, checksum: 15af104392b53c8bad1ec441601ddd44 (MD5) Previous issue date: 2016-03-23Conselho Nacional de Desenvolvimento Científico e Tecnológico - CNPqapplication/pdfhttp://tede.bc.uepb.edu.br/jspui/retrieve/6146/PDF%20-%20Renata%20Cardoso%20Oliveira.pdf.jpgporUniversidade Estadual da ParaíbaPrograma de Pós-Graduação em Saúde Pública - PPGSPUEPBBrasilPró-Reitoria de Pós-Graduação e Pesquisa - PRPGPSíndrome metabólicaAterosclerose clínicaDoenças cardiovascularesDoenças das artérias carótidasMetabolic syndromeCardiovascular diseasesCarotid rrtery diseasesSAUDE COLETIVA::SAUDE PUBLICASíndrome metabólica e aterosclerose subclínica em adolescentes: Uma avaliação dos critérios diagnósticosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis-4979121372796375736006006005248714503811102783112649244584600979info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UEPBinstname:Universidade Estadual da Paraíba (UEPB)instacron:UEPBTHUMBNAILPDF - Renata Cardoso Oliveira.pdf.jpgPDF - Renata Cardoso Oliveira.pdf.jpgimage/jpeg3884http://tede.bc.uepb.edu.br/jspui/bitstream/tede/2785/3/PDF+-+Renata+Cardoso+Oliveira.pdf.jpg7d992f857d43adc9c98df7e7535c7251MD53ORIGINALPDF - Renata Cardoso Oliveira.pdfPDF - Renata Cardoso Oliveira.pdfapplication/pdf19968885http://tede.bc.uepb.edu.br/jspui/bitstream/tede/2785/2/PDF+-+Renata+Cardoso+Oliveira.pdf15af104392b53c8bad1ec441601ddd44MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81960http://tede.bc.uepb.edu.br/jspui/bitstream/tede/2785/1/license.txt6052ae61e77222b2086e666b7ae213ceMD51tede/27852017-07-21 01:09:25.98oai:tede.bc.uepb.edu.br: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Biblioteca Digital de Teses e Dissertaçõeshttp://tede.bc.uepb.edu.br/jspui/PUBhttp://tede.bc.uepb.edu.br/oai/requestbc@uepb.edu.br||opendoar:2017-07-21T04:09:25Biblioteca Digital de Teses e Dissertações da UEPB - Universidade Estadual da Paraíba (UEPB)false |
dc.title.por.fl_str_mv |
Síndrome metabólica e aterosclerose subclínica em adolescentes: Uma avaliação dos critérios diagnósticos |
title |
Síndrome metabólica e aterosclerose subclínica em adolescentes: Uma avaliação dos critérios diagnósticos |
spellingShingle |
Síndrome metabólica e aterosclerose subclínica em adolescentes: Uma avaliação dos critérios diagnósticos Oliveira, Renata Cardoso Síndrome metabólica Aterosclerose clínica Doenças cardiovasculares Doenças das artérias carótidas Metabolic syndrome Cardiovascular diseases Carotid rrtery diseases SAUDE COLETIVA::SAUDE PUBLICA |
title_short |
Síndrome metabólica e aterosclerose subclínica em adolescentes: Uma avaliação dos critérios diagnósticos |
title_full |
Síndrome metabólica e aterosclerose subclínica em adolescentes: Uma avaliação dos critérios diagnósticos |
title_fullStr |
Síndrome metabólica e aterosclerose subclínica em adolescentes: Uma avaliação dos critérios diagnósticos |
title_full_unstemmed |
Síndrome metabólica e aterosclerose subclínica em adolescentes: Uma avaliação dos critérios diagnósticos |
title_sort |
Síndrome metabólica e aterosclerose subclínica em adolescentes: Uma avaliação dos critérios diagnósticos |
author |
Oliveira, Renata Cardoso |
author_facet |
Oliveira, Renata Cardoso |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Medeiros, Carla Campos Muniz |
dc.contributor.advisor1ID.fl_str_mv |
64135667449 |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/6730680514230870 |
dc.contributor.referee1.fl_str_mv |
Coura, Alexsandro Silva |
dc.contributor.referee1Lattes.fl_str_mv |
http://lattes.cnpq.br/5597558131874152 |
dc.contributor.referee2.fl_str_mv |
Vianna, Rodrigo Pinheiro de Toledo |
dc.contributor.referee2Lattes.fl_str_mv |
http://lattes.cnpq.br/3915051035089861 |
dc.contributor.authorID.fl_str_mv |
08895315448 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/0956324322195962 |
dc.contributor.author.fl_str_mv |
Oliveira, Renata Cardoso |
contributor_str_mv |
Medeiros, Carla Campos Muniz Coura, Alexsandro Silva Vianna, Rodrigo Pinheiro de Toledo |
dc.subject.por.fl_str_mv |
Síndrome metabólica Aterosclerose clínica Doenças cardiovasculares Doenças das artérias carótidas |
topic |
Síndrome metabólica Aterosclerose clínica Doenças cardiovasculares Doenças das artérias carótidas Metabolic syndrome Cardiovascular diseases Carotid rrtery diseases SAUDE COLETIVA::SAUDE PUBLICA |
dc.subject.eng.fl_str_mv |
Metabolic syndrome Cardiovascular diseases Carotid rrtery diseases |
dc.subject.cnpq.fl_str_mv |
SAUDE COLETIVA::SAUDE PUBLICA |
description |
Introduction: epidemiological evidence show strong links of the metabolic syndrome with subclinical atherosclerosis. Objective: to identify the best diagnosis of metabolic syndrome criteria to detect thickening of the intima-media complex of the carotid in adolescents. Methods: cross-sectional study with a quantitative approach, developed in 512 adolescents from public schools aged between 15 and 19 years between September 2012 and June 2013. For diagnosis of metabolic syndrome were used two criteria of the International Diabetes Federation and the NationalCholesterolEducationProgram / AdultTreatmentPanel III adapted by Cook. It was considered marked thickening of the average complex carotid intimal, when the value was equal to or greater than + 2Z. To evaluate the association between the criteria of the metabolic syndrome and thickening of the intimal average carotid complex we used the chi-square test was also evaluated the positive and negative preditivio value of each criterion to detect thickening. To verify the agreement of the two diagnostic criteria was used the Kappa test. We used SPSS version 22.0 and 95% confidence interval. Results: metabolic syndrome and systolic blood pressure changes identified by NationalCholesterolEducationProgram / AdultTreatment PanelIII adapted by COOK was associated with thickening of the intima-media complex-carotid (p = 0.020, p = 0.030, respectively). Metabolic syndrome was diagnosed by two criteria in 19.2% (<0.001) with low agreement, kappa of 0.28. The diagnostic criteria that had the highest positive predictive value was NationalCholesterolEducationProgram / AdultTreatmentPanel III adapted by COOK 15%. Conclusion: the NationalCholesterolEducationProgram / AdultTreatmentPanel III adapted by COOK was the criterion that was associated with the presence of thickening of the intima-media complex of the carotid. |
publishDate |
2016 |
dc.date.issued.fl_str_mv |
2016-03-23 |
dc.date.accessioned.fl_str_mv |
2017-07-20T12:18:56Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/masterThesis |
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masterThesis |
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publishedVersion |
dc.identifier.citation.fl_str_mv |
OLIVEIRA, R. C. Síndrome metabólica e aterosclerose subclínica em adolescentes: Uma avaliação dos critérios diagnósticos. 2016. 85f. Dissertação (Programa de Pós-Graduação em Saúde Pública - PPGSP) - Universidade Estadual da Paraíba, Campina Grande, 2016. |
dc.identifier.uri.fl_str_mv |
http://tede.bc.uepb.edu.br/tede/jspui/handle/tede/2785 |
identifier_str_mv |
OLIVEIRA, R. C. Síndrome metabólica e aterosclerose subclínica em adolescentes: Uma avaliação dos critérios diagnósticos. 2016. 85f. Dissertação (Programa de Pós-Graduação em Saúde Pública - PPGSP) - Universidade Estadual da Paraíba, Campina Grande, 2016. |
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http://tede.bc.uepb.edu.br/tede/jspui/handle/tede/2785 |
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por |
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por |
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Universidade Estadual da Paraíba |
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UEPB |
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Brasil |
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Universidade Estadual da Paraíba |
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