Associação entre obesidade e mortalidade por câncer no Brasil.

• Autor(a) principal: Magalhâes, Manuel Armando Ribeiro
• Data de Publicação: 2016
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: Biblioteca Digital de Teses e Dissertações da UERJ
• Texto Completo: http://www.bdtd.uerj.br/handle/1/4343
• topic: Cancer; Obesity; Association; Body mass index; Câncer; Obesidade; Associação; Índice de massa corporal; CNPQ::CIENCIAS DA SAUDE::SAUDE COLETIVA::EPIDEMIOLOGIA

Due to the change in the distribution pattern of diseases, with the rise of chronic noncommunicable diseases, including cancer, as well as its magnitude and obesity as public health problems, recent studies seek to evaluate the association between obesity and cancer. Many meta-analyzes of cohort studies and case-control have pointed to the existence of association between obesity and esophageal cancer (adenocarcinoma only), colon, rectum, kidney, liver, gall bladder, endometrial, breast, leukemias, malignant melanoma and pancreas. Therefore, it is important to evaluate this association in our context, considering the lack of studies of this approach in Brazil and the evidence from the international literature to point out the obesity and overweight as a risk factor for some of the types of cancers incidents in Brazil. The aim of this study is to evaluate the correlation between obesity and mortality from different types of cancer in the brazilian population. This is an ecological study in which the units of analysis were the federation units. The mortality data were extracted from DATASUS for individuals over 20 years from 2006 to 2013. The mortality rate was standardized for age and then was calculated the moving average of three years. The obesity prevalence was estimated from the data of the brazilian Household Budget Survey (2002-2003). Partial correlation coefficients were calculated between the prevalence of obesity and standardized mortality rates for each type of cancer studied, stratified by sex; the adjustment variables were average per capita income and prevalence of smokers by state. Were included in the analyzes the esophagus, colon, rectum, kidney, gallbladder, pancreas, endometrium and female breast cancers. The results suggest there is an association between obesity and all kinds of cancers studied for males with partial correlation coefficients ranging from 0.54 to 0.66. For females the coefficients ranged from -0.14 to 0.21 between the types of cancers studied, indicating no correlation or weak correlation in both directions, with no statistical significance.