Soro-reatividade para hidatidose policística e análise sócio-epidemiológica em Sena Madureira, Acre - Brasil

• Autor(a) principal: Pereira, Thaís Martins
• Data de Publicação: 2014
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: Biblioteca Digital de Teses e Dissertações da UERJ
• Texto Completo: http://www.bdtd.uerj.br/handle/1/14422
• topic: Echinococcus vogeli; Polycystic hidatidosis; Serosurvey; Acre; Echinococcus vogeli; Hidatidose policística; Levantamento epidemiológico; Acre; Doenças parasitárias Epidemiologia; Echinococcus vogeli; Fígado Equinococose; Análise parasitológica; CNPQ::CIENCIAS BIOLOGICAS::PARASITOLOGIA::HELMINTOLOGIA DE PARASITOS

Polycystic hydatid disease is a neglected zoonosis caused by the larval of cestode, Echinococcus vogeli, in inhabitants of the neotropical rainforests. Hunting and feeding dogs with bushmeat are common habits among suspected or confirmed individuals with polycystic hydatidosis The diagnosis is based on clinical findings (especially abdominal mass), results of image analysis and detection of antybodies by Immunoblot test, which has been described for patients with the chronic form of the disease. Only at this stage, the patients seeking medical care. This study aims to evaluate the reactivity for polycystic hydatid disease, evaluate the presence of intestinal parasites and characterize the epidemiological factors in individuals living in two regions of forest in Sena Madureira (Acre). The participants in this study agreed to participate after consideration of the Term of Consent. A questionnaire identifying information like address, gender, age and hunting habits were obtained. Blood samples were collected from 125 inhabitants of the protected area (Floresta Estadual do Antimary) and another unit no environmental conservation in Sena Madureira, where 207 blood samples were obtained. Sera were processed by the Immunoblot test for the detection of IgG in 1:100 and 1:10, in the Laboratório de Referência Nacional em Hidatidose - IOC - Fiocruz. In Unit conservation, 39.2% of subjects were positive and 17,4% in another area. It has been demonstrated that there is significant difference between areas, although the correlation is low. The most reactive individuals in both areas showed bands of 40kDa and 28kDa. In both regions showed no significant difference in the reactive and age. The habit of hunting among the reactive was 100% of individuals practicing hunting in the conservation unit and the unit no maintenance was 88.9% of subjects. The presences of one to three dogs were predominant in both areas. The practice of hunting and the presence of dogs had no significant association with serologic reactivity in both areas. The occupation of reactive individuals in both regions was predominantly farmers and students. Regarding the parasitological examination we found no parasite in reactive individuals who might have immune cross-reaction test for hydatid disease. It s concluded that there is difference in reactivity between the areas, and the conservation unit has highest number of reactive individuals. There was no association between reactivity, gender, age, hunting and the presence of dogs. Reactive individuals also had intestinal parasites, but these are not related to possible cross-reaction in the Immunoblot test. The presence of 40kDa and 28kDa bands in the Immunoblot test can be seen in the serological profile of individuals from endemic areas that have already come into contact with the parasite.