Adesão à profilaxia farmacológica de tromboembolismo venoso por pacientes submetidos a cirurgias ortopédicas
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da UERJ |
Texto Completo: | http://www.bdtd.uerj.br/handle/1/8680 |
Resumo: | Venous thromboembolism (VTE) is a phenomenon caused by the formation of thrombus related to venous stasis, endothelial lesion and hypercoagulability. Orthopedic surgeries, especially knee and hip arthroplasties, are risk factors for the occurrence of VTE with the recommendation of extended postoperative pharmacological prophylaxis. This study aimed to identify the adherence profile to the pharmacological prophylaxis of VTE in patients submitted to knee or hip arthroplasty, from August 2017 to September 2018, at the University Hospital of the Federal University of Maranhão UHFUMA, São Luís. A descriptive-observational cross-sectional study was conducted with adult patients who underwent pharmacotherapeutic follow-up at the hospital and in the postoperative period during outpatient return visits. To measure adhesion the Morisky Medication Adherence Scale (MMAS 8) was applied. Were related factors related to self-perception, social and economic, clinical condition and pharmacotherapy of the patients with thromboprophylaxis adherence. The results presented correspond to the follow-up of 70 patients characterized predominantly by the female sex, age over 60 years, with up to 4 years of study and income of 2 to 3 minimum wages. Clinical data show that the majority need to perform hip arthroplasty surgery (85.7%), had some chronic disease (65.7%) and were polymedicated (70.0%). The anticoagulant prescribed at hospital discharge was rivaroxaban. A percentage of 82.9% showed knowledge about the purpose of the anticoagulant and almost 93.0% knew the way to use it, with good and excellent acceptance of prophylaxis. Adherence analysis by the Morisky Medication Adherence Scale showed that in 73.0% of the patients adherence, while 27.0% were not adherent to thromboprophylaxis. Had mayor adherence that patients who did not need guidance during follow-up, they reported good and excellent acceptance prophylaxis, although polymedicated during discharge. The data obtained allowed us to conclude that there was a limiting factor for complete drug adherence to VTE prophylaxis, performed with rivaroxaban, in patients with low socioeconomic conditions, who underwent hip or knee arthroplasty. |
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Oliveira, Liszt Palmeira dehttp://lattes.cnpq.br/1024131957905197Fontenele, Andréa Martins Melohttp://lattes.cnpq.br/0426142737886855Couto Neto, Bernardohttp://lattes.cnpq.br/5104701625414448Batista, Luiz Albertohttp://lattes.cnpq.br/5830308657213148Britto, Maria Helena Seabra Soares dehttp://lattes.cnpq.br/9442764969909044http://lattes.cnpq.br/7138354149817328Viana, Leandra Marla Aires Travassos2021-01-05T19:40:26Z2019-12-192019-09-20VIANA, Leandra Marla Aires Travassos. Adesão à profilaxia farmacológica de tromboembolismo venoso por pacientes submetidos a cirurgias ortopédicas. 2019. 87 f. Dissertação (Mestrado em Ciências Médicas) - Universidade do Estado do Rio de Janeiro, Rio de Janeiro, 2019.http://www.bdtd.uerj.br/handle/1/8680Venous thromboembolism (VTE) is a phenomenon caused by the formation of thrombus related to venous stasis, endothelial lesion and hypercoagulability. Orthopedic surgeries, especially knee and hip arthroplasties, are risk factors for the occurrence of VTE with the recommendation of extended postoperative pharmacological prophylaxis. This study aimed to identify the adherence profile to the pharmacological prophylaxis of VTE in patients submitted to knee or hip arthroplasty, from August 2017 to September 2018, at the University Hospital of the Federal University of Maranhão UHFUMA, São Luís. A descriptive-observational cross-sectional study was conducted with adult patients who underwent pharmacotherapeutic follow-up at the hospital and in the postoperative period during outpatient return visits. To measure adhesion the Morisky Medication Adherence Scale (MMAS 8) was applied. Were related factors related to self-perception, social and economic, clinical condition and pharmacotherapy of the patients with thromboprophylaxis adherence. The results presented correspond to the follow-up of 70 patients characterized predominantly by the female sex, age over 60 years, with up to 4 years of study and income of 2 to 3 minimum wages. Clinical data show that the majority need to perform hip arthroplasty surgery (85.7%), had some chronic disease (65.7%) and were polymedicated (70.0%). The anticoagulant prescribed at hospital discharge was rivaroxaban. A percentage of 82.9% showed knowledge about the purpose of the anticoagulant and almost 93.0% knew the way to use it, with good and excellent acceptance of prophylaxis. Adherence analysis by the Morisky Medication Adherence Scale showed that in 73.0% of the patients adherence, while 27.0% were not adherent to thromboprophylaxis. Had mayor adherence that patients who did not need guidance during follow-up, they reported good and excellent acceptance prophylaxis, although polymedicated during discharge. The data obtained allowed us to conclude that there was a limiting factor for complete drug adherence to VTE prophylaxis, performed with rivaroxaban, in patients with low socioeconomic conditions, who underwent hip or knee arthroplasty.O tromboembolismo venoso (TEV) é um fenômeno ocasionado pela formação de trombos relacionado com a estase venosa, lesão endotelial e hipercoagulabilidade. As cirurgias ortopédicas, especialmente as artroplastias de joelho e quadril são consideradas fatores de risco para a ocorrência de TEV, com recomendação de profilaxia farmacológica estendida no pós-operatório. Este estudo buscou identificar o perfil de adesão à profilaxia farmacológica do TEV em pacientes submetidos a artroplastia de joelho ou quadril, no período de agosto de 2017 a setembro de 2018, no Hospital Universitário da Universidade Federal do Maranhão HUUFMA, São Luís. Foi realizado um estudo transversal do tipo descritivo-observacionalcom pacientes adultos que tiveram acompanhamento farmacoterapêuticona internação e no pós-operatório, durante as consultas de retorno ambulatorial. Para medir a adesão foi aplicada a Escala de Adesão Terapêutica de Morisky. Foram relacionados os fatores referentes à auto-percepção, sociais e econômicos,condição clínica efarmacoterapiadospecientescom a adesão à tromboprofilaxia. Os resultados apresentados correspondem ao acompanhamento de 70 pacientes caracterizados predominantemente pelo sexo feminino, idade superior a 60 anos, com até 4 anos de estudo e renda de 2 a 3 salários mínimos. Os dados clínicos mostraram que a maioria necessitou realizar cirugia de artroplastia de quadril (85,7%), apresentava alguma doença crônica (65,7 %) e estavam polimedicados (70,0%). O anticoagulante prescrito na alta hospitalar foi o rivaroxabana.Um percentual de 82,9 % demonstrou conhecimento sobre a finalidade do anticoagulantee quase 93 % conhecia bem a forma de usá-lo, com relato de boa e ótima aceitação à profilaxia.A análise da adesão pela Escala Terapêutica de Morisky mostrou que houve adesão ao tratamento em 73,0% dos pacientes, enquanto 27,0%não foram aderentes à tromboprofilaxia. Tiveram maior adesão os pacientes que não necessitaram de orientação durante o acompanhamento, relataram boa e ótima aceitação à profilaxia, embora polimedicados durante a alta hospitalar. Os dados obtidos permitiram concluir que a reduzida condição sócio econômica constituiu-se num fator limitante para a completa adesão medicamentosa à profilaxia de TEV, realizada com rivaroxabana, em pacientes submetidos a artroplastia de quadril ou joelho.Submitted by Boris Flegr (boris@uerj.br) on 2021-01-05T19:40:26Z No. of bitstreams: 1 Leandra Marla Aires Travassos Viana Dissertacao completa.pdf: 1221584 bytes, checksum: d3b7a018e3e61237df2a7b92f5e92bd5 (MD5)Made available in DSpace on 2021-01-05T19:40:26Z (GMT). No. of bitstreams: 1 Leandra Marla Aires Travassos Viana Dissertacao completa.pdf: 1221584 bytes, checksum: d3b7a018e3e61237df2a7b92f5e92bd5 (MD5) Previous issue date: 2019-09-20application/pdfporUniversidade do Estado do Rio de JaneiroPrograma de Pós-Graduação em Ciências MédicasUERJBRCentro Biomédico::Faculdade de Ciências MédicasDrug adherenceProphylaxisAnticoagulantsArthroplastyThromboembolismTromboembolia venosaArtroplastiaTratamento farmacológicoPrevenção de doençasAdesão medicamentosaAnticoagulantesArtroplastiaProfilaxiaTromboembolismoTromboembolismoAnticoagulantesCNPQ::CIENCIAS DA SAUDE::FARMACIAAdesão à profilaxia farmacológica de tromboembolismo venoso por pacientes submetidos a cirurgias ortopédicasAdherence to pharmacological prophylaxis of venous thromboembolism in patients submitted to orthopedic surgeriesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UERJinstname:Universidade do Estado do Rio de Janeiro (UERJ)instacron:UERJORIGINALLeandra Marla Aires Travassos Viana Dissertacao completa.pdfapplication/pdf1221584http://www.bdtd.uerj.br/bitstream/1/8680/1/Leandra+Marla+Aires+Travassos+Viana+Dissertacao+completa.pdfd3b7a018e3e61237df2a7b92f5e92bd5MD511/86802024-02-26 16:00:17.754oai:www.bdtd.uerj.br:1/8680Biblioteca Digital de Teses e Dissertaçõeshttp://www.bdtd.uerj.br/PUBhttps://www.bdtd.uerj.br:8443/oai/requestbdtd.suporte@uerj.bropendoar:29032024-02-26T19:00:17Biblioteca Digital de Teses e Dissertações da UERJ - Universidade do Estado do Rio de Janeiro (UERJ)false |
dc.title.por.fl_str_mv |
Adesão à profilaxia farmacológica de tromboembolismo venoso por pacientes submetidos a cirurgias ortopédicas |
dc.title.alternative.eng.fl_str_mv |
Adherence to pharmacological prophylaxis of venous thromboembolism in patients submitted to orthopedic surgeries |
title |
Adesão à profilaxia farmacológica de tromboembolismo venoso por pacientes submetidos a cirurgias ortopédicas |
spellingShingle |
Adesão à profilaxia farmacológica de tromboembolismo venoso por pacientes submetidos a cirurgias ortopédicas Viana, Leandra Marla Aires Travassos Drug adherence Prophylaxis Anticoagulants Arthroplasty Thromboembolism Tromboembolia venosa Artroplastia Tratamento farmacológico Prevenção de doenças Adesão medicamentosa Anticoagulantes Artroplastia Profilaxia Tromboembolismo Tromboembolismo Anticoagulantes CNPQ::CIENCIAS DA SAUDE::FARMACIA |
title_short |
Adesão à profilaxia farmacológica de tromboembolismo venoso por pacientes submetidos a cirurgias ortopédicas |
title_full |
Adesão à profilaxia farmacológica de tromboembolismo venoso por pacientes submetidos a cirurgias ortopédicas |
title_fullStr |
Adesão à profilaxia farmacológica de tromboembolismo venoso por pacientes submetidos a cirurgias ortopédicas |
title_full_unstemmed |
Adesão à profilaxia farmacológica de tromboembolismo venoso por pacientes submetidos a cirurgias ortopédicas |
title_sort |
Adesão à profilaxia farmacológica de tromboembolismo venoso por pacientes submetidos a cirurgias ortopédicas |
author |
Viana, Leandra Marla Aires Travassos |
author_facet |
Viana, Leandra Marla Aires Travassos |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Oliveira, Liszt Palmeira de |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/1024131957905197 |
dc.contributor.referee1.fl_str_mv |
Fontenele, Andréa Martins Melo |
dc.contributor.referee1Lattes.fl_str_mv |
http://lattes.cnpq.br/0426142737886855 |
dc.contributor.referee2.fl_str_mv |
Couto Neto, Bernardo |
dc.contributor.referee2Lattes.fl_str_mv |
http://lattes.cnpq.br/5104701625414448 |
dc.contributor.referee3.fl_str_mv |
Batista, Luiz Alberto |
dc.contributor.referee3Lattes.fl_str_mv |
http://lattes.cnpq.br/5830308657213148 |
dc.contributor.referee4.fl_str_mv |
Britto, Maria Helena Seabra Soares de |
dc.contributor.referee4Lattes.fl_str_mv |
http://lattes.cnpq.br/9442764969909044 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/7138354149817328 |
dc.contributor.author.fl_str_mv |
Viana, Leandra Marla Aires Travassos |
contributor_str_mv |
Oliveira, Liszt Palmeira de Fontenele, Andréa Martins Melo Couto Neto, Bernardo Batista, Luiz Alberto Britto, Maria Helena Seabra Soares de |
dc.subject.eng.fl_str_mv |
Drug adherence Prophylaxis Anticoagulants Arthroplasty Thromboembolism |
topic |
Drug adherence Prophylaxis Anticoagulants Arthroplasty Thromboembolism Tromboembolia venosa Artroplastia Tratamento farmacológico Prevenção de doenças Adesão medicamentosa Anticoagulantes Artroplastia Profilaxia Tromboembolismo Tromboembolismo Anticoagulantes CNPQ::CIENCIAS DA SAUDE::FARMACIA |
dc.subject.por.fl_str_mv |
Tromboembolia venosa Artroplastia Tratamento farmacológico Prevenção de doenças Adesão medicamentosa Anticoagulantes Artroplastia Profilaxia Tromboembolismo Tromboembolismo Anticoagulantes |
dc.subject.cnpq.fl_str_mv |
CNPQ::CIENCIAS DA SAUDE::FARMACIA |
description |
Venous thromboembolism (VTE) is a phenomenon caused by the formation of thrombus related to venous stasis, endothelial lesion and hypercoagulability. Orthopedic surgeries, especially knee and hip arthroplasties, are risk factors for the occurrence of VTE with the recommendation of extended postoperative pharmacological prophylaxis. This study aimed to identify the adherence profile to the pharmacological prophylaxis of VTE in patients submitted to knee or hip arthroplasty, from August 2017 to September 2018, at the University Hospital of the Federal University of Maranhão UHFUMA, São Luís. A descriptive-observational cross-sectional study was conducted with adult patients who underwent pharmacotherapeutic follow-up at the hospital and in the postoperative period during outpatient return visits. To measure adhesion the Morisky Medication Adherence Scale (MMAS 8) was applied. Were related factors related to self-perception, social and economic, clinical condition and pharmacotherapy of the patients with thromboprophylaxis adherence. The results presented correspond to the follow-up of 70 patients characterized predominantly by the female sex, age over 60 years, with up to 4 years of study and income of 2 to 3 minimum wages. Clinical data show that the majority need to perform hip arthroplasty surgery (85.7%), had some chronic disease (65.7%) and were polymedicated (70.0%). The anticoagulant prescribed at hospital discharge was rivaroxaban. A percentage of 82.9% showed knowledge about the purpose of the anticoagulant and almost 93.0% knew the way to use it, with good and excellent acceptance of prophylaxis. Adherence analysis by the Morisky Medication Adherence Scale showed that in 73.0% of the patients adherence, while 27.0% were not adherent to thromboprophylaxis. Had mayor adherence that patients who did not need guidance during follow-up, they reported good and excellent acceptance prophylaxis, although polymedicated during discharge. The data obtained allowed us to conclude that there was a limiting factor for complete drug adherence to VTE prophylaxis, performed with rivaroxaban, in patients with low socioeconomic conditions, who underwent hip or knee arthroplasty. |
publishDate |
2019 |
dc.date.available.fl_str_mv |
2019-12-19 |
dc.date.issued.fl_str_mv |
2019-09-20 |
dc.date.accessioned.fl_str_mv |
2021-01-05T19:40:26Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
VIANA, Leandra Marla Aires Travassos. Adesão à profilaxia farmacológica de tromboembolismo venoso por pacientes submetidos a cirurgias ortopédicas. 2019. 87 f. Dissertação (Mestrado em Ciências Médicas) - Universidade do Estado do Rio de Janeiro, Rio de Janeiro, 2019. |
dc.identifier.uri.fl_str_mv |
http://www.bdtd.uerj.br/handle/1/8680 |
identifier_str_mv |
VIANA, Leandra Marla Aires Travassos. Adesão à profilaxia farmacológica de tromboembolismo venoso por pacientes submetidos a cirurgias ortopédicas. 2019. 87 f. Dissertação (Mestrado em Ciências Médicas) - Universidade do Estado do Rio de Janeiro, Rio de Janeiro, 2019. |
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http://www.bdtd.uerj.br/handle/1/8680 |
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Universidade do Estado do Rio de Janeiro |
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UERJ |
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BR |
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Centro Biomédico::Faculdade de Ciências Médicas |
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Universidade do Estado do Rio de Janeiro |
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