Custo-efetividade das aplicações profissionais de verniz fluoretado em pré-escolares: revisão sistemática

Detalhes bibliográficos
Autor(a) principal: D'Hypollito, Izabel Monteiro
Data de Publicação: 2020
Outros Autores: izabelmdh@gmail.com
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Biblioteca Digital de Teses e Dissertações da UERJ
Texto Completo: http://www.bdtd.uerj.br/handle/1/19149
Resumo: The aim of this study was to conduct an economic evaluation of the professional fuoride varnish application in preschoolers through a systematic review. Electronic searches were performed in the MEDLINE databases via pubmed, SCOPUS, EMBASE, CENTRAL, WEB OF SCIENCE, LILACS, BBO, BVS Health economics, and a handsearch in eleven specialized journals and in the Thesis and Dissertation Bank BDTD. Inclusion criteria were: complete economic evaluation conducted through economic modeling or direct clinical intervention, with children of preschool age, in which fluoride varnish was used for caries control compared to placebo, standard care or no intervention. The records were imported into the EndNote Web program and then exported to a Microsoft Excel® spreadsheet. Two researchers independently performed the selection and data extraction independently. The risk of bias in the included studies was assessed using the “Drummond check-list 2005” (clinical trials with economic evaluation) and “Philips 2004” (modeling) tools. After removing duplicates, 2285 articles remained, whose titles and abstracts were evaluated, and 168 articles were selected for reading in full. At the end of the process, 8 studies were included, all of them “cost-effectiveness” type, with five models and three clinical trials with economic evaluation. No study had a low risk of bias. The direct comparison between the results was difficult due to the great heterogeneity of the included studies. Three studies found a cost-effective result for fluoride varnish in preschoolers, but in one of these, the other interventions had even more cost-effective results than varnish. The other authors reported a large increase in costs caused by the application of varnish and / or low cost-effectiveness. Data such as these question the use of fluoride varnish in caries control as a public health policy and should be considered when setting priorities in the allocation of resources for more cost-effective interventions.
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spelling Santos, Ana Paula Pires doshttp://lattes.cnpq.br/8258756998579769Vieira, Branca Heloisa de Oliveira Martinshttp://lattes.cnpq.br/2733765551807694Andrade, Fernanda Barja Fidalgo Silva dehttp://lattes.cnpq.br/0960854816665570França, Adilis Kalina Alexandria dehttp://lattes.cnpq.br/8813744643679880Castro, Rodolfo de Almeida Limahttp://lattes.cnpq.br/8918299610523931http://lattes.cnpq.br/0381207784109314D'Hypollito, Izabel Monteiroizabelmdh@gmail.com2023-03-13T17:26:50Z2020-02-17D’HYPPOLITO, Izabel Monteiro. Custo-efetividade das aplicações profissionais de verniz fluoretado em pré-escolares: revisão sistemática. 2020. 81 f. Dissertação (Mestrado em Odontologia) – Faculdade de Odontologia, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, 2020.http://www.bdtd.uerj.br/handle/1/19149The aim of this study was to conduct an economic evaluation of the professional fuoride varnish application in preschoolers through a systematic review. Electronic searches were performed in the MEDLINE databases via pubmed, SCOPUS, EMBASE, CENTRAL, WEB OF SCIENCE, LILACS, BBO, BVS Health economics, and a handsearch in eleven specialized journals and in the Thesis and Dissertation Bank BDTD. Inclusion criteria were: complete economic evaluation conducted through economic modeling or direct clinical intervention, with children of preschool age, in which fluoride varnish was used for caries control compared to placebo, standard care or no intervention. The records were imported into the EndNote Web program and then exported to a Microsoft Excel® spreadsheet. Two researchers independently performed the selection and data extraction independently. The risk of bias in the included studies was assessed using the “Drummond check-list 2005” (clinical trials with economic evaluation) and “Philips 2004” (modeling) tools. After removing duplicates, 2285 articles remained, whose titles and abstracts were evaluated, and 168 articles were selected for reading in full. At the end of the process, 8 studies were included, all of them “cost-effectiveness” type, with five models and three clinical trials with economic evaluation. No study had a low risk of bias. The direct comparison between the results was difficult due to the great heterogeneity of the included studies. Three studies found a cost-effective result for fluoride varnish in preschoolers, but in one of these, the other interventions had even more cost-effective results than varnish. The other authors reported a large increase in costs caused by the application of varnish and / or low cost-effectiveness. Data such as these question the use of fluoride varnish in caries control as a public health policy and should be considered when setting priorities in the allocation of resources for more cost-effective interventions.O objetivo deste estudo foi realizar uma avaliação econômica da aplicação profissional de verniz fluoretado em pré-escolares através de uma revisão sistemática. Foram realizadas buscas eletrônicas nas bases de dados MEDLINE via pubmed, SCOPUS, EMBASE, CENTRAL, WEB OF SCIENCE, LILACS, BBO, BVS Economia em saúde, e uma busca manual em onze periódicos especializados e no Banco de Teses e dissertações BDTD. Os critérios de inclusão foram: estudos de avaliação econômica completa conduzidos através de modelagem econômica ou intervenção clínica direta, com crianças em idade pré-escolar, em que o verniz fluoretado fosse usado para o controle da cárie em comparação placebo, cuidado padrão ou nenhuma intervenção. Os registros foram importados para o programa EndNote Web e depois exportados para uma planilha Microsoft Excel®. Duas pesquisadoras realizaram a seleção e a extração de dados de forma independente. O risco de viés dos estudos incluídos foi avaliado através das ferramentas “Drummond check-list 2005” (ensaios clínicos com avaliação econômica) e “Philips 2004” (modelagem). Após a remoção das duplicatas, restaram 2285 artigos, cujos títulos e resumos foram avaliados, tendo sido selecionados 168 artigos para leitura na íntegra. Ao final, 8 estudos foram incluídos, todos do tipo “custo-efetividade”, sendo cinco modelagens e três ensaios clínicos com avaliação econômica. Nenhum estudo apresentou baixo risco de viés. A comparação direta entre os resultados foi dificultada devido à grande heterogeneidade dos estudos incluídos. Três estudos encontram um resultado custo-efetivo para o verniz fluoretado em pré-escolares porém em um destes as outras intervenções tiveram resultados ainda mais custo-efetivos que o verniz. Os demais autores relataram um grande aumento nos custos provocados pela aplicação de verniz e/ou baixo custo-efetividade. Dados como esses põem em dúvida o uso do verniz fluoretado no controle de cárie como política de saúde pública e devem ser considerados ao se estabelecer prioridades na alocação de recursos para intervenções mais custo-efetivas.Submitted by Kárin CB/B (karin@uerj.br) on 2023-03-13T17:26:50Z No. of bitstreams: 1 Dissertação - Izabel Monteiro DHyppolito - 2020 - Completa.pdf: 3192456 bytes, checksum: 6e1b9b8d34f1a3b2e5b21d9902f84eb0 (MD5)Made available in DSpace on 2023-03-13T17:26:50Z (GMT). No. of bitstreams: 1 Dissertação - Izabel Monteiro DHyppolito - 2020 - Completa.pdf: 3192456 bytes, checksum: 6e1b9b8d34f1a3b2e5b21d9902f84eb0 (MD5) Previous issue date: 2020-02-17Conselho Nacional de Desenvolvimento Científico e Tecnológico - CNPqFundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro - FAPERJapplication/pdfporUniversidade do Estado do Rio de JaneiroPrograma de Pós-Graduação em OdontologiaUERJBrasilCentro Biomédico::Faculdade de OdontologiaDental cariesChild, preschoolFluoride varnishCosts and cost analysisEvidence-based dentistrySystematic reviewCárie dentáriaPré-escolarVerniz fluoretadoCustos e análise de custoOdontologia baseada em evidênciaRevisão sistemáticaCIENCIAS DA SAUDE::ODONTOLOGIACusto-efetividade das aplicações profissionais de verniz fluoretado em pré-escolares: revisão sistemáticaCost-effectiveness of professional fluoride varnish applications in preschoolers: systematic reviewinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UERJinstname:Universidade do Estado do Rio de Janeiro (UERJ)instacron:UERJORIGINALDissertação - Izabel Monteiro DHyppolito - 2020 - Completa.pdfDissertação - Izabel Monteiro DHyppolito - 2020 - Completa.pdfapplication/pdf3192456http://www.bdtd.uerj.br/bitstream/1/19149/2/Disserta%C3%A7%C3%A3o+-+Izabel+Monteiro+DHyppolito+-+2020+-+Completa.pdf6e1b9b8d34f1a3b2e5b21d9902f84eb0MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82123http://www.bdtd.uerj.br/bitstream/1/19149/1/license.txte5502652da718045d7fcd832b79fca29MD511/191492024-02-26 20:13:06.666oai:www.bdtd.uerj.br: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Biblioteca Digital de Teses e Dissertaçõeshttp://www.bdtd.uerj.br/PUBhttps://www.bdtd.uerj.br:8443/oai/requestbdtd.suporte@uerj.bropendoar:29032024-02-26T23:13:06Biblioteca Digital de Teses e Dissertações da UERJ - Universidade do Estado do Rio de Janeiro (UERJ)false
dc.title.por.fl_str_mv Custo-efetividade das aplicações profissionais de verniz fluoretado em pré-escolares: revisão sistemática
dc.title.alternative.eng.fl_str_mv Cost-effectiveness of professional fluoride varnish applications in preschoolers: systematic review
title Custo-efetividade das aplicações profissionais de verniz fluoretado em pré-escolares: revisão sistemática
spellingShingle Custo-efetividade das aplicações profissionais de verniz fluoretado em pré-escolares: revisão sistemática
D'Hypollito, Izabel Monteiro
Dental caries
Child, preschool
Fluoride varnish
Costs and cost analysis
Evidence-based dentistry
Systematic review
Cárie dentária
Pré-escolar
Verniz fluoretado
Custos e análise de custo
Odontologia baseada em evidência
Revisão sistemática
CIENCIAS DA SAUDE::ODONTOLOGIA
title_short Custo-efetividade das aplicações profissionais de verniz fluoretado em pré-escolares: revisão sistemática
title_full Custo-efetividade das aplicações profissionais de verniz fluoretado em pré-escolares: revisão sistemática
title_fullStr Custo-efetividade das aplicações profissionais de verniz fluoretado em pré-escolares: revisão sistemática
title_full_unstemmed Custo-efetividade das aplicações profissionais de verniz fluoretado em pré-escolares: revisão sistemática
title_sort Custo-efetividade das aplicações profissionais de verniz fluoretado em pré-escolares: revisão sistemática
author D'Hypollito, Izabel Monteiro
author_facet D'Hypollito, Izabel Monteiro
izabelmdh@gmail.com
author_role author
author2 izabelmdh@gmail.com
author2_role author
dc.contributor.advisor1.fl_str_mv Santos, Ana Paula Pires dos
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/8258756998579769
dc.contributor.advisor2.fl_str_mv Vieira, Branca Heloisa de Oliveira Martins
dc.contributor.advisor2Lattes.fl_str_mv http://lattes.cnpq.br/2733765551807694
dc.contributor.referee1.fl_str_mv Andrade, Fernanda Barja Fidalgo Silva de
dc.contributor.referee1Lattes.fl_str_mv http://lattes.cnpq.br/0960854816665570
dc.contributor.referee2.fl_str_mv França, Adilis Kalina Alexandria de
dc.contributor.referee2Lattes.fl_str_mv http://lattes.cnpq.br/8813744643679880
dc.contributor.referee3.fl_str_mv Castro, Rodolfo de Almeida Lima
dc.contributor.referee3Lattes.fl_str_mv http://lattes.cnpq.br/8918299610523931
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/0381207784109314
dc.contributor.author.fl_str_mv D'Hypollito, Izabel Monteiro
izabelmdh@gmail.com
contributor_str_mv Santos, Ana Paula Pires dos
Vieira, Branca Heloisa de Oliveira Martins
Andrade, Fernanda Barja Fidalgo Silva de
França, Adilis Kalina Alexandria de
Castro, Rodolfo de Almeida Lima
dc.subject.eng.fl_str_mv Dental caries
Child, preschool
Fluoride varnish
Costs and cost analysis
Evidence-based dentistry
Systematic review
topic Dental caries
Child, preschool
Fluoride varnish
Costs and cost analysis
Evidence-based dentistry
Systematic review
Cárie dentária
Pré-escolar
Verniz fluoretado
Custos e análise de custo
Odontologia baseada em evidência
Revisão sistemática
CIENCIAS DA SAUDE::ODONTOLOGIA
dc.subject.por.fl_str_mv Cárie dentária
Pré-escolar
Verniz fluoretado
Custos e análise de custo
Odontologia baseada em evidência
Revisão sistemática
dc.subject.cnpq.fl_str_mv CIENCIAS DA SAUDE::ODONTOLOGIA
description The aim of this study was to conduct an economic evaluation of the professional fuoride varnish application in preschoolers through a systematic review. Electronic searches were performed in the MEDLINE databases via pubmed, SCOPUS, EMBASE, CENTRAL, WEB OF SCIENCE, LILACS, BBO, BVS Health economics, and a handsearch in eleven specialized journals and in the Thesis and Dissertation Bank BDTD. Inclusion criteria were: complete economic evaluation conducted through economic modeling or direct clinical intervention, with children of preschool age, in which fluoride varnish was used for caries control compared to placebo, standard care or no intervention. The records were imported into the EndNote Web program and then exported to a Microsoft Excel® spreadsheet. Two researchers independently performed the selection and data extraction independently. The risk of bias in the included studies was assessed using the “Drummond check-list 2005” (clinical trials with economic evaluation) and “Philips 2004” (modeling) tools. After removing duplicates, 2285 articles remained, whose titles and abstracts were evaluated, and 168 articles were selected for reading in full. At the end of the process, 8 studies were included, all of them “cost-effectiveness” type, with five models and three clinical trials with economic evaluation. No study had a low risk of bias. The direct comparison between the results was difficult due to the great heterogeneity of the included studies. Three studies found a cost-effective result for fluoride varnish in preschoolers, but in one of these, the other interventions had even more cost-effective results than varnish. The other authors reported a large increase in costs caused by the application of varnish and / or low cost-effectiveness. Data such as these question the use of fluoride varnish in caries control as a public health policy and should be considered when setting priorities in the allocation of resources for more cost-effective interventions.
publishDate 2020
dc.date.issued.fl_str_mv 2020-02-17
dc.date.accessioned.fl_str_mv 2023-03-13T17:26:50Z
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dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
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dc.identifier.citation.fl_str_mv D’HYPPOLITO, Izabel Monteiro. Custo-efetividade das aplicações profissionais de verniz fluoretado em pré-escolares: revisão sistemática. 2020. 81 f. Dissertação (Mestrado em Odontologia) – Faculdade de Odontologia, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, 2020.
dc.identifier.uri.fl_str_mv http://www.bdtd.uerj.br/handle/1/19149
identifier_str_mv D’HYPPOLITO, Izabel Monteiro. Custo-efetividade das aplicações profissionais de verniz fluoretado em pré-escolares: revisão sistemática. 2020. 81 f. Dissertação (Mestrado em Odontologia) – Faculdade de Odontologia, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, 2020.
url http://www.bdtd.uerj.br/handle/1/19149
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dc.publisher.none.fl_str_mv Universidade do Estado do Rio de Janeiro
dc.publisher.program.fl_str_mv Programa de Pós-Graduação em Odontologia
dc.publisher.initials.fl_str_mv UERJ
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv Centro Biomédico::Faculdade de Odontologia
publisher.none.fl_str_mv Universidade do Estado do Rio de Janeiro
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