Timerosal contido em vacinas e o transtorno do espectro autista: uma revisão de literatura

• Autor(a) principal: Pires, Vinícius da Silva
• Data de Publicação: 2017
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: Biblioteca Digital de Teses e Dissertações da UERJ
• Texto Completo: http://www.bdtd.uerj.br/handle/1/11084
• topic: Environmental engineering; Autism; Vaccination; Thimerosal; Thiomersal; Autism; Engenharia ambiental; Autismo; Vacinação; Timerosal; Etilmercúrio; Transtorno do Espectro Autista; CNPQ::ENGENHARIAS

Autistic Spectrum Disorder (TEA), previously considered a rare disorder, has a higher prevalence than childhood cancer, diabetes, and Down syndrome. Over the last few years, there has been an exponential increase in the number of researches on environmental factors associated with ASD, among which the Epidemiological Studies of association between ASD and Thimerosal Contained in Vaccines (TCV) stand out. Analyzing the progress of these studies, as well as verifying if there is a consensus among the researchers, was the objective of this research. The databases of PubMed, Scopus and Virtual Health Library (VHL) for articles published between the years 2000 and 2017 were examined using the English terms Thimerosal, Thiomersal, Ethilmercury; "Autism Spectrum Disorder" and "Autism" for placement of combined titles and texts. Twenty-three articles were chosen. The research concluded that despite a change in the study designs, with Case-Control studies prevailing in recent years, the limitations found in the methodology of the articles at the beginning of the period remained practically unchanged, without significant evolutions. It was also observed that there was no consensus among US researchers about the association between thimerosal and ASD, however, in all other countries, all authors concluded that there was no association.