Estudo da ancestralidade paterna em amostras de populações do Estado do Rio de Janeiro e do Oeste Africano: uma dinâmica populacional

• Autor(a) principal: Oliveira, Andréa Maria de
• Data de Publicação: 2015
• Tipo de documento: Tese
• Idioma: por
• Título da fonte: Biblioteca Digital de Teses e Dissertações da UERJ
• Texto Completo: http://www.bdtd.uerj.br/handle/1/16163
• topic: Africa; Y-STR; Y-SNP; Population studies; Ancestry; África; Y-STR; Y-SNP; Estudos populacionais; Ancestralidade; África; Rio de Janeiro (RJ) - População; Grupos populacionais - Genética; Variações genéticas; Genética das populações; CNPQ::CIENCIAS BIOLOGICAS::GENETICA::GENETICA HUMANA E MEDICA

The use of STR and SNP markers has proved to be of great importance to discriminate individuals of the same population as well as for evolutionary studies. The use of a set of 17 STRs and 46 SNPs specific from the Y chromosome allowed the characterization of a group of samples representative of the Rio de Janeiro and the West African populations, with a deep assessment of the paternal ancestry. The first part of this study focused in the analysis of 605 males of the state of Rio de Janeiro. The results showed no significant differences between the Brazilian southeastern populations and Rio de Janeiro, which showed high values of haplotype (0.9999 ± 0.0001) and haplogroup (0.7589 ± 0.0171) diversities. The second part of the study revealed a high haplotype diversity (1.0000 ± 0.0018) in a sample from West Africa. The value of haplogroup diversity (0.6895 ± 0.0200) was similar to those previously seen in the West and Center African Bantu populations, mainly from Benin, Nigeria and Ivory Coast. The third part of this study showed no significant differences between the African component of our sample from Rio de Janeiro and the Southeastern, Western and Midwestern African populations. On the other hand, significant differences were observed when comparing the samples of the African component in Rio de Janeiro and of West Africa with population samples from Uganda, Kenya and South Africa. The increase of genetic studies in African populations is important for a better understanding of world genetic diversity. This work provided new genetic data, which can be added to those already available, expanding our knowledge about the formation of other populations also influenced by the African Diaspora.