Avaliação do estado nutricional de pacientes com doença inflamatória intestinal
Autor(a) principal: | |
---|---|
Data de Publicação: | 2011 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da UERJ |
Texto Completo: | http://www.bdtd.uerj.br/handle/1/12735 |
Resumo: | Inflammatory Bowel Disease (IBD) is a disorder characterized by diffuse inflammation of the gastrointestinal tract. The two main types of IBD are ulcerative colitis (UC) and Crohn's disease (CD), both coursing with important changes in nutritional status (NS). The objective of this study was to identify differences in body composition between patients with CD, UC, and healthy subjects and to compare the NS of these three groups of patients, adjusting for factors that can interfere in NS such as current use of corticosteroids, physical activity, disease activity, age and sex. It was conducted a cross-sectional study which included 101 patients with IBD (50 with CD and 51 with UC) and 35 healthy subjects, selected at the Ambulatory of Pedro Ernesto University Hospital (HUPE) of the Rio de Janeiro State University (UERJ). Socio-demographic and personal information such as physical activity, smoking, prior diseases and previous surgical procedures were collected. Other necessary information for the research were collected from medical records. The anthropometric evaluation was carried out through the following measures: body weight; height; mid-arm, waist and hip circumferences; skinfold thickness of the triceps, subscapular, suprailiac, and thigh; and mid-arm muscle circumference (MAMC). The body composition analysis was performed by bioelectrical impedance (BIA) using the equipment Biodynamics model 450®. The laboratory variables analyzed, included: glucose, complete blood count, lipid profile, total protein, albumin, globulin, erythrocyte sedimentation rate, and C-reactive protein. Weight, body mass index, waist circumference, and percentage body fat calculated from skinfold measurements were lower in CD patients compared to healthy subjects and/or the patients with UC. The MAMC was lower in patients with CD and UC compared to healthy subjects, but without showing differences between the two groups of patients. Through BIA, it was found that CD patients had values of lean body mass, body cell mass, extracellular mass, total body water, and extracellular water smaller when compared to healthy subjects. Seric levels of total cholesterol, total protein, and albumin, as well as red blood cell count and relative count of lymphocytes were lower in the individuals with CD than the individuals of the control group and/or the patients with UC. Patients with UC exhibit body composition similar to that of the healthy population. In contrast, CD patients have widely NS committed with depletion of body fat and lean mass in relation to other individuals. |
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Marques, Ruy Garciahttp://lattes.cnpq.br/9834395683414025Diestel, Cristina Fajardohttp://lattes.cnpq.br/7595570980356913Carvalho, Ana Teresa Pugashttp://lattes.cnpq.br/2218519959842896Lopes, Gustavo Casimirohttp://lattes.cnpq.br/8143521576246390Klein, Márcia Regina Simas Torreshttp://lattes.cnpq.br/8755810383117085http://lattes.cnpq.br/2430577113710917Ramos, Beatriz Peixoto2021-01-06T20:57:34Z2012-05-112011-07-28RAMOS, Beatriz Peixoto. Avaliação do estado nutricional de pacientes com doença inflamatória intestinal. 2011. 88 f. Dissertação (Mestrado em Fisiopatologia Clínica e Experimental) - Universidade do Estado do Rio de Janeiro, Rio de Janeiro, 2011.http://www.bdtd.uerj.br/handle/1/12735Inflammatory Bowel Disease (IBD) is a disorder characterized by diffuse inflammation of the gastrointestinal tract. The two main types of IBD are ulcerative colitis (UC) and Crohn's disease (CD), both coursing with important changes in nutritional status (NS). The objective of this study was to identify differences in body composition between patients with CD, UC, and healthy subjects and to compare the NS of these three groups of patients, adjusting for factors that can interfere in NS such as current use of corticosteroids, physical activity, disease activity, age and sex. It was conducted a cross-sectional study which included 101 patients with IBD (50 with CD and 51 with UC) and 35 healthy subjects, selected at the Ambulatory of Pedro Ernesto University Hospital (HUPE) of the Rio de Janeiro State University (UERJ). Socio-demographic and personal information such as physical activity, smoking, prior diseases and previous surgical procedures were collected. Other necessary information for the research were collected from medical records. The anthropometric evaluation was carried out through the following measures: body weight; height; mid-arm, waist and hip circumferences; skinfold thickness of the triceps, subscapular, suprailiac, and thigh; and mid-arm muscle circumference (MAMC). The body composition analysis was performed by bioelectrical impedance (BIA) using the equipment Biodynamics model 450®. The laboratory variables analyzed, included: glucose, complete blood count, lipid profile, total protein, albumin, globulin, erythrocyte sedimentation rate, and C-reactive protein. Weight, body mass index, waist circumference, and percentage body fat calculated from skinfold measurements were lower in CD patients compared to healthy subjects and/or the patients with UC. The MAMC was lower in patients with CD and UC compared to healthy subjects, but without showing differences between the two groups of patients. Through BIA, it was found that CD patients had values of lean body mass, body cell mass, extracellular mass, total body water, and extracellular water smaller when compared to healthy subjects. Seric levels of total cholesterol, total protein, and albumin, as well as red blood cell count and relative count of lymphocytes were lower in the individuals with CD than the individuals of the control group and/or the patients with UC. Patients with UC exhibit body composition similar to that of the healthy population. In contrast, CD patients have widely NS committed with depletion of body fat and lean mass in relation to other individuals.A doença Inflamatória Intestinal (DII) é uma desordem caracterizada pela inflamação crônica do trato gastrointestinal. Os dois principais tipos de DII são a Retocolite Ulcerativa (RCU) e a Doença de Crohn (DC) e ambas cursam com importantes alterações no estado nutricional (EN). O objetivo deste estudo foi identificar as diferenças na composição corporal entre pacientes com DC, RCU e indivíduos saudáveis, além de comparar o estado nutricional dos três grupos de pacientes, ajustando para fatores que podem interferir no EN, como o uso atual de corticosteróides, a atividade física, a atividade de doença, a idade e o sexo. Foi realizado um estudo transversal que incluiu 101 pacientes com DII (50 com DC e 51 com RCU) e 35 indivíduos saudáveis, selecionados no Ambulatório do Hospital Universitário Pedro Ernesto (HUPE) da Universidade do Estado do Rio de Janeiro (UERJ). Foram colhidas informações sócio-demográficas e pessoais, tais como: prática de atividade física, tabagismo, doenças pregressas e procedimentos cirúrgicos prévios. Outras informações necessárias à pesquisa foram coletadas em prontuário médico. A avaliação antropométrica foi realizada por meio das seguintes medidas: peso corporal; altura; circunferências do braço, da cintura (CC) e do quadril; dobras cutâneas do tríceps, subescápula, supra-ilíaca e da coxa; e circunferência muscular do braço (CMB). A análise da composição corporal foi realizada por meio da bioimpedância elétrica (BIA), utilizando-se o aparelho Biodynamics modelo 450®. As variáveis laboratoriais analisadas foram: glicose, hemograma completo, perfil lipídico, proteínas totais, albumina, globulina, velocidade de hemossedimentação e proteína C reativa. O peso, o índice de massa corporal, a CC e o percentual de gordura corporal calculado a partir da aferição das dobras cutâneas, foram menores nos pacientes com DC, quando comparados aos indivíduos saudáveis e/ou aos pacientes com RCU. A CMB foi menor nos pacientes com DC e RCU quando comparados aos indivíduos saudáveis, porém sem apresentar diferenças entre os dois grupos de pacientes. Por BIA, verificou-se que os pacientes com DC apresentaram valores de massa magra, massa celular corpórea, massa extracelular, água corporal total e água extracelular menores quando comparados aos indivíduos saudáveis. Os níveis séricos de colesterol total, proteínas totais e albumina, e a contagem total de hemácias foram menores nos indivíduos com DC quando comparados aos indivíduos do grupo controle e/ou aos indivíduos do grupo da RCU. Os pacientes com RCU exibem composição corporal semelhante à da população saudável. Em contraposição, os pacientes com DC apresentam EN amplamente comprometido com depleção de gordura corporal e massa magra em relação aos demais indivíduosSubmitted by Boris Flegr (boris@uerj.br) on 2021-01-06T20:57:34Z No. of bitstreams: 1 Beatriz Peixoto Ramos Dissertacao completa.pdf: 510616 bytes, checksum: 093e861f92e2ae387edc922c0718e2f3 (MD5)Made available in DSpace on 2021-01-06T20:57:34Z (GMT). No. of bitstreams: 1 Beatriz Peixoto Ramos Dissertacao completa.pdf: 510616 bytes, checksum: 093e861f92e2ae387edc922c0718e2f3 (MD5) Previous issue date: 2011-07-28application/pdfporUniversidade do Estado do Rio de JaneiroPrograma de Pós-Graduação em Fisiopatologia Clínica e ExperimentalUERJBRCentro Biomédico::Faculdade de Ciências MédicasInflammatory bowel diseaseUlcerative colitisBody compositionNutrition statusBioelectrical impedance analysisNutritional assessmentIntestines - Inflammatory diseasesGastroenterologyCrohn's DiseaseProctocolitisDoença inflamatória intestinalDoença de CrohnRetocolite ulcerativaComposição corporalBioimpedância elétricaAvaliação nutricionalIntestinos Doenças inflamatóriasGastroenterologiaCrohn, Doença deProctocoliteCNPQ::CIENCIAS DA SAUDE::NUTRICAOAvaliação do estado nutricional de pacientes com doença inflamatória intestinalNutrition status of patients with inflammatory bowel diseaseinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UERJinstname:Universidade do Estado do Rio de Janeiro (UERJ)instacron:UERJORIGINALBeatriz Peixoto Ramos Dissertacao completa.pdfapplication/pdf510616http://www.bdtd.uerj.br/bitstream/1/12735/1/Beatriz+Peixoto+Ramos+Dissertacao+completa.pdf093e861f92e2ae387edc922c0718e2f3MD511/127352024-02-26 16:36:35.257oai:www.bdtd.uerj.br:1/12735Biblioteca Digital de Teses e Dissertaçõeshttp://www.bdtd.uerj.br/PUBhttps://www.bdtd.uerj.br:8443/oai/requestbdtd.suporte@uerj.bropendoar:29032024-02-26T19:36:35Biblioteca Digital de Teses e Dissertações da UERJ - Universidade do Estado do Rio de Janeiro (UERJ)false |
dc.title.por.fl_str_mv |
Avaliação do estado nutricional de pacientes com doença inflamatória intestinal |
dc.title.alternative.eng.fl_str_mv |
Nutrition status of patients with inflammatory bowel disease |
title |
Avaliação do estado nutricional de pacientes com doença inflamatória intestinal |
spellingShingle |
Avaliação do estado nutricional de pacientes com doença inflamatória intestinal Ramos, Beatriz Peixoto Inflammatory bowel disease Ulcerative colitis Body composition Nutrition status Bioelectrical impedance analysis Nutritional assessment Intestines - Inflammatory diseases Gastroenterology Crohn's Disease Proctocolitis Doença inflamatória intestinal Doença de Crohn Retocolite ulcerativa Composição corporal Bioimpedância elétrica Avaliação nutricional Intestinos Doenças inflamatórias Gastroenterologia Crohn, Doença de Proctocolite CNPQ::CIENCIAS DA SAUDE::NUTRICAO |
title_short |
Avaliação do estado nutricional de pacientes com doença inflamatória intestinal |
title_full |
Avaliação do estado nutricional de pacientes com doença inflamatória intestinal |
title_fullStr |
Avaliação do estado nutricional de pacientes com doença inflamatória intestinal |
title_full_unstemmed |
Avaliação do estado nutricional de pacientes com doença inflamatória intestinal |
title_sort |
Avaliação do estado nutricional de pacientes com doença inflamatória intestinal |
author |
Ramos, Beatriz Peixoto |
author_facet |
Ramos, Beatriz Peixoto |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Marques, Ruy Garcia |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/9834395683414025 |
dc.contributor.advisor-co1.fl_str_mv |
Diestel, Cristina Fajardo |
dc.contributor.advisor-co1Lattes.fl_str_mv |
http://lattes.cnpq.br/7595570980356913 |
dc.contributor.referee1.fl_str_mv |
Carvalho, Ana Teresa Pugas |
dc.contributor.referee1Lattes.fl_str_mv |
http://lattes.cnpq.br/2218519959842896 |
dc.contributor.referee2.fl_str_mv |
Lopes, Gustavo Casimiro |
dc.contributor.referee2Lattes.fl_str_mv |
http://lattes.cnpq.br/8143521576246390 |
dc.contributor.referee3.fl_str_mv |
Klein, Márcia Regina Simas Torres |
dc.contributor.referee3Lattes.fl_str_mv |
http://lattes.cnpq.br/8755810383117085 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/2430577113710917 |
dc.contributor.author.fl_str_mv |
Ramos, Beatriz Peixoto |
contributor_str_mv |
Marques, Ruy Garcia Diestel, Cristina Fajardo Carvalho, Ana Teresa Pugas Lopes, Gustavo Casimiro Klein, Márcia Regina Simas Torres |
dc.subject.eng.fl_str_mv |
Inflammatory bowel disease Ulcerative colitis Body composition Nutrition status Bioelectrical impedance analysis Nutritional assessment Intestines - Inflammatory diseases Gastroenterology Crohn's Disease Proctocolitis |
topic |
Inflammatory bowel disease Ulcerative colitis Body composition Nutrition status Bioelectrical impedance analysis Nutritional assessment Intestines - Inflammatory diseases Gastroenterology Crohn's Disease Proctocolitis Doença inflamatória intestinal Doença de Crohn Retocolite ulcerativa Composição corporal Bioimpedância elétrica Avaliação nutricional Intestinos Doenças inflamatórias Gastroenterologia Crohn, Doença de Proctocolite CNPQ::CIENCIAS DA SAUDE::NUTRICAO |
dc.subject.por.fl_str_mv |
Doença inflamatória intestinal Doença de Crohn Retocolite ulcerativa Composição corporal Bioimpedância elétrica Avaliação nutricional Intestinos Doenças inflamatórias Gastroenterologia Crohn, Doença de Proctocolite |
dc.subject.cnpq.fl_str_mv |
CNPQ::CIENCIAS DA SAUDE::NUTRICAO |
description |
Inflammatory Bowel Disease (IBD) is a disorder characterized by diffuse inflammation of the gastrointestinal tract. The two main types of IBD are ulcerative colitis (UC) and Crohn's disease (CD), both coursing with important changes in nutritional status (NS). The objective of this study was to identify differences in body composition between patients with CD, UC, and healthy subjects and to compare the NS of these three groups of patients, adjusting for factors that can interfere in NS such as current use of corticosteroids, physical activity, disease activity, age and sex. It was conducted a cross-sectional study which included 101 patients with IBD (50 with CD and 51 with UC) and 35 healthy subjects, selected at the Ambulatory of Pedro Ernesto University Hospital (HUPE) of the Rio de Janeiro State University (UERJ). Socio-demographic and personal information such as physical activity, smoking, prior diseases and previous surgical procedures were collected. Other necessary information for the research were collected from medical records. The anthropometric evaluation was carried out through the following measures: body weight; height; mid-arm, waist and hip circumferences; skinfold thickness of the triceps, subscapular, suprailiac, and thigh; and mid-arm muscle circumference (MAMC). The body composition analysis was performed by bioelectrical impedance (BIA) using the equipment Biodynamics model 450®. The laboratory variables analyzed, included: glucose, complete blood count, lipid profile, total protein, albumin, globulin, erythrocyte sedimentation rate, and C-reactive protein. Weight, body mass index, waist circumference, and percentage body fat calculated from skinfold measurements were lower in CD patients compared to healthy subjects and/or the patients with UC. The MAMC was lower in patients with CD and UC compared to healthy subjects, but without showing differences between the two groups of patients. Through BIA, it was found that CD patients had values of lean body mass, body cell mass, extracellular mass, total body water, and extracellular water smaller when compared to healthy subjects. Seric levels of total cholesterol, total protein, and albumin, as well as red blood cell count and relative count of lymphocytes were lower in the individuals with CD than the individuals of the control group and/or the patients with UC. Patients with UC exhibit body composition similar to that of the healthy population. In contrast, CD patients have widely NS committed with depletion of body fat and lean mass in relation to other individuals. |
publishDate |
2011 |
dc.date.issued.fl_str_mv |
2011-07-28 |
dc.date.available.fl_str_mv |
2012-05-11 |
dc.date.accessioned.fl_str_mv |
2021-01-06T20:57:34Z |
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masterThesis |
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RAMOS, Beatriz Peixoto. Avaliação do estado nutricional de pacientes com doença inflamatória intestinal. 2011. 88 f. Dissertação (Mestrado em Fisiopatologia Clínica e Experimental) - Universidade do Estado do Rio de Janeiro, Rio de Janeiro, 2011. |
dc.identifier.uri.fl_str_mv |
http://www.bdtd.uerj.br/handle/1/12735 |
identifier_str_mv |
RAMOS, Beatriz Peixoto. Avaliação do estado nutricional de pacientes com doença inflamatória intestinal. 2011. 88 f. Dissertação (Mestrado em Fisiopatologia Clínica e Experimental) - Universidade do Estado do Rio de Janeiro, Rio de Janeiro, 2011. |
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http://www.bdtd.uerj.br/handle/1/12735 |
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Universidade do Estado do Rio de Janeiro |
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Programa de Pós-Graduação em Fisiopatologia Clínica e Experimental |
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UERJ |
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BR |
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Centro Biomédico::Faculdade de Ciências Médicas |
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Universidade do Estado do Rio de Janeiro |
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