Efeito do tratamento periodontal em pacientes com doença renal crônica

• Autor(a) principal: Antunes, Susyane Almeida de Souza
• Data de Publicação: 2007
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: Biblioteca Digital de Teses e Dissertações da UERJ
• Texto Completo: http://www.bdtd.uerj.br/handle/1/14162
• topic: Periodontitis; Periodontal treatment; Chronic kidney disease; Glomerular filtration; Periodontite; Tratamento periodontal; Doença renal crônica; Filtração glomerular; Periodontia; CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA

The aim of the present study was to evaluate to effect of periodontal treatment in chronic renal disease (CRD) patients. 26 patients with CRD stages 3 and 4 with moderate and severe chronic periodontitis received periodontal basic therapy. Periodontal clinical parameters included plaque index (PI), bleeding on probing (BOP), probing pocket depth (PPD) and probing attachment level (PAL). Estimated glomerular filtration rate (ml/min/1.73m2) and serum levels of C-reactive protein (CRP) (mg/dl), triglicerids (mg/dl), total cholesterol (mg/dl) and albumin (g/dl) were collected on days 0 and 90, after periodontal treatment. On day 0, mean % of sites with PPD &#8805; 4mm and PAL &#8805; 4mm were 23,7 (± 11) e 38,2 (± 16,5), respectively. On day 90, the corresponding values decreased to 13,3 (± 8,0) e 33,4 (±16,6). The mean % of sites with PPD &#8805; 6mm and PAL &#8805; 6mm decreased from 7,8 (±8,6) and 24,5 (±19,3) to 2,9 (±5,1) e 23,8 (±20,3), respectively (P<0,05). On day 0, the mean values of CRP, albumin, triglicerids and total cholesterol was a statistically 1,0 mg/dl (±1,0), 4,4 g/dl (±0,4), 160 mg/dl (±61,5), 200,1 mg/dl (±36,9), while the the corresponding values for day 90 were 0,8 mg/dl (0,6), 4,4 g/dl (0,3), 155,8 mg/dl (65,6), 199,5 mg/dl (46), respectively. On day 90, the levels of estimated glomerular filtration rate were 41,6 ml/min/1.73m2 (±13,1), and on day 90 the corresponding values were 45 ml/min/1.73m2 (±15,7) (p<0.05). The clinical significance of this improvement on estimated glomerular filtration rate is questionable. Further longitudinal studies with longer observation periods are necessary to evaluate if periodontal therapy may be beneficial for CRD patients.