Determinants of lead exposure in children on the outskirts of Salvador, Brazil

Detalhes bibliográficos
Autor(a) principal: Menezes Filho, José Antônio
Data de Publicação: 2012
Outros Autores: Viana, Gustavo Freitas de Sousa, Paes, Ciro Rodrigues
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/15616
Resumo: Texto completo: acesso restrito. p. 2593-2603
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spelling Menezes Filho, José AntônioViana, Gustavo Freitas de SousaPaes, Ciro RodriguesMenezes Filho, José AntônioViana, Gustavo Freitas de SousaPaes, Ciro Rodrigues2014-08-13T17:46:14Z20120167-6369http://repositorio.ufba.br/ri/handle/ri/15616v. 184, n. 4Texto completo: acesso restrito. p. 2593-2603Lead (Pb) is a toxic heavy metal that is widely distributed throughout the environment. Pb is an important neurotoxic metal and children are more susceptible to its effect due to their higher absorption rate and greater susceptibility of the developing nervous system. In this work, we evaluated the lead exposure levels in children living near a metallurgical plant and identified risk factors associated with its internal dose. All children, aged 1–10 years and 11 months, living near a metallurgical plant in the great Salvador area, Brazil were evaluated in this cross-sectional study and compared with children from a non exposed area. Occipital hair and blood were used to assess exposure. Air lead levels in the respirable fraction (PM2.5) were also measured in both areas. Blood lead levels (BLL), hair lead levels (PbH) and air lead were determined by graphite furnace atomic absorption spectrometry. Spearman correlations analysis was used to evaluate correlations between BLL, PbH and descriptors. Significant risk factors were modeled using multivariate linear regression analysis. Air lead levels were approximately ten-folds lower than EPA reference concentration (0.15 μg/m3). Median BLL and PbH were1.65 ± 1.45 μg/dL and 1.26 ± 3.70 μg/g, respectively, in exposed children. In the referents, medians were BLL 1.20 ± 1.20 μg/dL; PbH 2.09 ± 2.06 μg/g. No significant difference was observed in biomarkers levels between boys and girls. It was observed a positive weak correlation (Spearman rho = 0.197, p = 0.033) between BLL and PbH. Our data show that children’s lead body burden measured as BLL or PbH are low when compared with the recommended reference values. Despite that, we were able to identify four risk factors associated with increased biological lead levels: age, living near industrial site, environmental tobacco smoking and, above all, domestic waste burning. In order to prevent such avoidable exposure, environmental education and proper waste management should be implemented, especially in developing countries.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-08-13T14:43:16Z No. of bitstreams: 1 José Antonio Menezes Filho.pdf: 527723 bytes, checksum: 5df4b18e1d543d054f4b5acec80e15ba (MD5)Approved for entry into archive by Patricia Barroso (pbarroso@ufba.br) on 2014-08-13T17:46:14Z (GMT) No. of bitstreams: 1 José Antonio Menezes Filho.pdf: 527723 bytes, checksum: 5df4b18e1d543d054f4b5acec80e15ba (MD5)Made available in DSpace on 2014-08-13T17:46:14Z (GMT). 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dc.title.pt_BR.fl_str_mv Determinants of lead exposure in children on the outskirts of Salvador, Brazil
dc.title.alternative.pt_BR.fl_str_mv Environmental Monitoring and Assessment
title Determinants of lead exposure in children on the outskirts of Salvador, Brazil
spellingShingle Determinants of lead exposure in children on the outskirts of Salvador, Brazil
Menezes Filho, José Antônio
Children
Lead body burden
Hair
Blood
Environmental tobacco smoking
title_short Determinants of lead exposure in children on the outskirts of Salvador, Brazil
title_full Determinants of lead exposure in children on the outskirts of Salvador, Brazil
title_fullStr Determinants of lead exposure in children on the outskirts of Salvador, Brazil
title_full_unstemmed Determinants of lead exposure in children on the outskirts of Salvador, Brazil
title_sort Determinants of lead exposure in children on the outskirts of Salvador, Brazil
author Menezes Filho, José Antônio
author_facet Menezes Filho, José Antônio
Viana, Gustavo Freitas de Sousa
Paes, Ciro Rodrigues
author_role author
author2 Viana, Gustavo Freitas de Sousa
Paes, Ciro Rodrigues
author2_role author
author
dc.contributor.author.fl_str_mv Menezes Filho, José Antônio
Viana, Gustavo Freitas de Sousa
Paes, Ciro Rodrigues
Menezes Filho, José Antônio
Viana, Gustavo Freitas de Sousa
Paes, Ciro Rodrigues
dc.subject.por.fl_str_mv Children
Lead body burden
Hair
Blood
Environmental tobacco smoking
topic Children
Lead body burden
Hair
Blood
Environmental tobacco smoking
description Texto completo: acesso restrito. p. 2593-2603
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2014-08-13T17:46:14Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/15616
dc.identifier.issn.none.fl_str_mv 0167-6369
dc.identifier.number.pt_BR.fl_str_mv v. 184, n. 4
identifier_str_mv 0167-6369
v. 184, n. 4
url http://repositorio.ufba.br/ri/handle/ri/15616
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.source.pt_BR.fl_str_mv http://dx.doi.org/ 10.1007/s10661-011-2137-0
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