Obtaining concomitant control of allergic rhinitis and asthma with a nasally inhaled corticosteroid

Detalhes bibliográficos
Autor(a) principal: Camargos, Paulo Augusto Moreira
Data de Publicação: 2007
Outros Autores: Ibiapina, C., Lasmar, L., Cruz Filho, Álvaro Augusto Souza da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/15990
Resumo: Texto completo: acesso restrito. p. 310–316
id UFBA-2_051d1429241d8dceb7778209dc5c23d8
oai_identifier_str oai:repositorio.ufba.br:ri/15990
network_acronym_str UFBA-2
network_name_str Repositório Institucional da UFBA
repository_id_str 1932
spelling Camargos, Paulo Augusto MoreiraIbiapina, C.Lasmar, L.Cruz Filho, Álvaro Augusto Souza daCamargos, Paulo Augusto MoreiraIbiapina, C.Lasmar, L.Cruz Filho, Álvaro Augusto Souza da2014-09-09T16:04:21Z20070105-4538http://repositorio.ufba.br/ri/handle/ri/15990v. 62, n. 3Texto completo: acesso restrito. p. 310–316Allergic rhinitis (AR) and asthma coexist frequently and a dual treatment is recommended by prescribing topical nasal plus oral inhaled corticosteroids. The purpose of this study was to assess the efficacy of a nasally inhaled corticosteroid aiming at concomitant control of AR and asthma. A controlled trial was conducted among 60 patients with AR and asthma, aged 6–18 years, who were randomized into two groups. During 8 weeks, the experimental group (30 patients) received exclusively fluticasone propionate hydrofluoroalkane (FP-HFA) inhaled through the nose (mouth closed) using a large volume spacer attached to a face mask. The comparison group (30 patients) received a nasal spray of isotonic saline plus oral inhalation of FP-HFA through a mouthpiece attached to the same spacer. Clinical scores for AR and asthma, nasal inspiratory peak flow (NIPF), and spirometry were assessed by blinded observers. There was a significant improvement in AR scores and NIPF in the experimental group (P ≤ 0.01) up to week 8, when a worsening was observed after the intervention was interrupted. Asthma symptoms score, forced expiratory volume (FEV)1, and FEF25−75% were not statistically different between groups at the baseline visit or along follow-up visits (P ≥ 0.20). Prebronchodilator FEV1 (% predicted value) improved by 10% in both groups, comparing values at inclusion with those obtained at the end of follow up. Our results suggest that nasally inhaled FP-HFA through a spacer may control AR and asthma in children and adolescents. This approach is likely to result in higher compliance, lower costs, and fewer side effects.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-03-11T12:37:14Z No. of bitstreams: 1 j.1398-9995.2007.01241.x.pdf: 522489 bytes, checksum: 04a9f82545b3668018d7be17881d0d10 (MD5)Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2014-09-09T16:04:21Z (GMT) No. of bitstreams: 1 j.1398-9995.2007.01241.x.pdf: 522489 bytes, checksum: 04a9f82545b3668018d7be17881d0d10 (MD5)Made available in DSpace on 2014-09-09T16:04:21Z (GMT). No. of bitstreams: 1 j.1398-9995.2007.01241.x.pdf: 522489 bytes, checksum: 04a9f82545b3668018d7be17881d0d10 (MD5) Previous issue date: 2007http://dx.doi.org/10.1111/j.1398-9995.2007.01241.xreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAAllergic rhinitisAsthmaInhaled corticosteroidObtaining concomitant control of allergic rhinitis and asthma with a nasally inhaled corticosteroidAllergyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALj.1398-9995.2007.01241.x.pdfj.1398-9995.2007.01241.x.pdfapplication/pdf522489https://repositorio.ufba.br/bitstream/ri/15990/1/j.1398-9995.2007.01241.x.pdf04a9f82545b3668018d7be17881d0d10MD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/15990/2/license.txt0d4b811ef71182510d2015daa7c8a900MD52TEXTj.1398-9995.2007.01241.x.pdf.txtj.1398-9995.2007.01241.x.pdf.txtExtracted texttext/plain31141https://repositorio.ufba.br/bitstream/ri/15990/3/j.1398-9995.2007.01241.x.pdf.txta15de5c794ca28f764b0d60b6e80cf70MD53ri/159902022-07-05 14:03:10.433oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:10Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Obtaining concomitant control of allergic rhinitis and asthma with a nasally inhaled corticosteroid
dc.title.alternative.pt_BR.fl_str_mv Allergy
title Obtaining concomitant control of allergic rhinitis and asthma with a nasally inhaled corticosteroid
spellingShingle Obtaining concomitant control of allergic rhinitis and asthma with a nasally inhaled corticosteroid
Camargos, Paulo Augusto Moreira
Allergic rhinitis
Asthma
Inhaled corticosteroid
title_short Obtaining concomitant control of allergic rhinitis and asthma with a nasally inhaled corticosteroid
title_full Obtaining concomitant control of allergic rhinitis and asthma with a nasally inhaled corticosteroid
title_fullStr Obtaining concomitant control of allergic rhinitis and asthma with a nasally inhaled corticosteroid
title_full_unstemmed Obtaining concomitant control of allergic rhinitis and asthma with a nasally inhaled corticosteroid
title_sort Obtaining concomitant control of allergic rhinitis and asthma with a nasally inhaled corticosteroid
author Camargos, Paulo Augusto Moreira
author_facet Camargos, Paulo Augusto Moreira
Ibiapina, C.
Lasmar, L.
Cruz Filho, Álvaro Augusto Souza da
author_role author
author2 Ibiapina, C.
Lasmar, L.
Cruz Filho, Álvaro Augusto Souza da
author2_role author
author
author
dc.contributor.author.fl_str_mv Camargos, Paulo Augusto Moreira
Ibiapina, C.
Lasmar, L.
Cruz Filho, Álvaro Augusto Souza da
Camargos, Paulo Augusto Moreira
Ibiapina, C.
Lasmar, L.
Cruz Filho, Álvaro Augusto Souza da
dc.subject.por.fl_str_mv Allergic rhinitis
Asthma
Inhaled corticosteroid
topic Allergic rhinitis
Asthma
Inhaled corticosteroid
description Texto completo: acesso restrito. p. 310–316
publishDate 2007
dc.date.issued.fl_str_mv 2007
dc.date.accessioned.fl_str_mv 2014-09-09T16:04:21Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/15990
dc.identifier.issn.none.fl_str_mv 0105-4538
dc.identifier.number.pt_BR.fl_str_mv v. 62, n. 3
identifier_str_mv 0105-4538
v. 62, n. 3
url http://repositorio.ufba.br/ri/handle/ri/15990
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1111/j.1398-9995.2007.01241.x
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
bitstream.url.fl_str_mv https://repositorio.ufba.br/bitstream/ri/15990/1/j.1398-9995.2007.01241.x.pdf
https://repositorio.ufba.br/bitstream/ri/15990/2/license.txt
https://repositorio.ufba.br/bitstream/ri/15990/3/j.1398-9995.2007.01241.x.pdf.txt
bitstream.checksum.fl_str_mv 04a9f82545b3668018d7be17881d0d10
0d4b811ef71182510d2015daa7c8a900
a15de5c794ca28f764b0d60b6e80cf70
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)
repository.mail.fl_str_mv
_version_ 1808459473142939648

Registros relacionados