Incidence of psychiatric side e¡ects during pegylated interferon- a retreatment in nonresponder hepatitisCvirus-infected patients

Detalhes bibliográficos
Autor(a) principal: Quarantini, Lucas de Castro
Data de Publicação: 2007
Outros Autores: Bressan, Rodrigo Affonseca, Galvão, Amanda, Neves, Susana Carolina Batista, Paraná, Raymundo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/5253
Resumo: p. 1098-1102
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spelling Quarantini, Lucas de CastroBressan, Rodrigo AffonsecaGalvão, AmandaNeves, Susana Carolina BatistaParaná, RaymundoQuarantini, Lucas de CastroBressan, Rodrigo AffonsecaGalvão, AmandaNeves, Susana Carolina BatistaParaná, Raymundo2012-01-25T18:08:47Z2012-01-25T18:08:47Z20071478-3231http://www.repositorio.ufba.br/ri/handle/ri/5253p. 1098-1102Objective: Evaluate the incidence of mental disorders using pegylated interferon plus ribavirin retreatment in nonresponder hepatitis C virus-infected patients. Method: The Mini-International Neuropsychiatric Interview (MINI) was used to evaluate 30 hepatitis C virus-infected interferon-nonresponder patients at baseline and following 4, 12 and 24 weeks of pegylated interferon retreatment. Results: During the pegylated interferon/ribavirin retreatment, 5(16.6%) patients developed psychiatric side effects: 3(10%) were diagnosed with major depressive disorder, 1(3.3%) had a brief psychotic disorder and 1(3.3%) presented with panic attacks. Conclusion: This is the first prospective study evaluating the incidence of neuropsychiatric side effects during interferon retreatment of hepatitis C virusinfected patients, suggesting that the risk of acquiring serious psychiatric symptoms during retreatment with interferon-a (IFN-a) may not be higher than during the first antiviral therapy. This finding challenges the hypothesis that during a second treatment with IFN-a, patients with hepatitis C may be at greater risk for neuropsychiatric side effects than naïve patients.Submitted by Ana Valéria de Jesus Moura (anavaleria_131@hotmail.com) on 2012-01-25T18:08:47Z No. of bitstreams: 1 j.1478-3231.2007.01532.x.pdf: 78602 bytes, checksum: bcefb41ffc42f3b9768fa639bc42f1ba (MD5)Made available in DSpace on 2012-01-25T18:08:47Z (GMT). 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dc.title.pt_BR.fl_str_mv Incidence of psychiatric side e¡ects during pegylated interferon- a retreatment in nonresponder hepatitisCvirus-infected patients
dc.title.alternative.pt_BR.fl_str_mv Liver International
title Incidence of psychiatric side e¡ects during pegylated interferon- a retreatment in nonresponder hepatitisCvirus-infected patients
spellingShingle Incidence of psychiatric side e¡ects during pegylated interferon- a retreatment in nonresponder hepatitisCvirus-infected patients
Quarantini, Lucas de Castro
comorbidity
hepatitis C
interferon
psychiatric side effects
retreatment
title_short Incidence of psychiatric side e¡ects during pegylated interferon- a retreatment in nonresponder hepatitisCvirus-infected patients
title_full Incidence of psychiatric side e¡ects during pegylated interferon- a retreatment in nonresponder hepatitisCvirus-infected patients
title_fullStr Incidence of psychiatric side e¡ects during pegylated interferon- a retreatment in nonresponder hepatitisCvirus-infected patients
title_full_unstemmed Incidence of psychiatric side e¡ects during pegylated interferon- a retreatment in nonresponder hepatitisCvirus-infected patients
title_sort Incidence of psychiatric side e¡ects during pegylated interferon- a retreatment in nonresponder hepatitisCvirus-infected patients
author Quarantini, Lucas de Castro
author_facet Quarantini, Lucas de Castro
Bressan, Rodrigo Affonseca
Galvão, Amanda
Neves, Susana Carolina Batista
Paraná, Raymundo
author_role author
author2 Bressan, Rodrigo Affonseca
Galvão, Amanda
Neves, Susana Carolina Batista
Paraná, Raymundo
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Quarantini, Lucas de Castro
Bressan, Rodrigo Affonseca
Galvão, Amanda
Neves, Susana Carolina Batista
Paraná, Raymundo
Quarantini, Lucas de Castro
Bressan, Rodrigo Affonseca
Galvão, Amanda
Neves, Susana Carolina Batista
Paraná, Raymundo
dc.subject.por.fl_str_mv comorbidity
hepatitis C
interferon
psychiatric side effects
retreatment
topic comorbidity
hepatitis C
interferon
psychiatric side effects
retreatment
description p. 1098-1102
publishDate 2007
dc.date.issued.fl_str_mv 2007
dc.date.accessioned.fl_str_mv 2012-01-25T18:08:47Z
dc.date.available.fl_str_mv 2012-01-25T18:08:47Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/5253
dc.identifier.issn.none.fl_str_mv 1478-3231
identifier_str_mv 1478-3231
url http://www.repositorio.ufba.br/ri/handle/ri/5253
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
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