Química e farmacologia de quimioterápicos antineoplásicos derivados de plantas

Detalhes bibliográficos
Autor(a) principal: Brandão, Hugo N.
Data de Publicação: 2010
Outros Autores: David, Juceni Pereira de Lima, Couto, Ricardo David, Nascimento, Jorge A. P., David, Jorge Mauricio
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/3782
Resumo: p. 1359-1369.
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spelling Brandão, Hugo N.David, Juceni Pereira de LimaCouto, Ricardo DavidNascimento, Jorge A. P.David, Jorge MauricioBrandão, Hugo N.David, Juceni Pereira de LimaCouto, Ricardo DavidNascimento, Jorge A. P.David, Jorge Mauricio2011-11-21T11:03:23Z2011-11-21T11:03:23Z20100100-4042http://www.repositorio.ufba.br/ri/handle/ri/3782v. 33, n. 6.p. 1359-1369.This review demonstrates the importance of plants as sources of molecules used in anticancer therapies. The approach is performed by relating the active molecules to their origins, details, mechanisms of action, structure-activity relationship and chemical characteristics of chemotherapeutical medicines. It was also described the development of anticancer agents from plants by the pharmaceutical industry and the difficulties to release these compounds as a trademark. These include the well known paclitaxel, docetaxel, vincristine, vinblastine, vinorelbine, vindesine, etoposide, teniposide, and other molecules that are undergoing clinical trials.Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2011-11-21T11:03:23Z No. of bitstreams: 1 26.pdf: 1108382 bytes, checksum: 01d593803fab5b4dc78b6fc49523b915 (MD5)Made available in DSpace on 2011-11-21T11:03:23Z (GMT). No. of bitstreams: 1 26.pdf: 1108382 bytes, checksum: 01d593803fab5b4dc78b6fc49523b915 (MD5) Previous issue date: 2010São PauloPlant antineoplasicsChemotherapicCancerQuímica e farmacologia de quimioterápicos antineoplásicos derivados de plantasQuímica Novainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleporreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAinfo:eu-repo/semantics/openAccessORIGINAL26.pdf26.pdfapplication/pdf1108382https://repositorio.ufba.br/bitstream/ri/3782/1/26.pdf01d593803fab5b4dc78b6fc49523b915MD51LICENSElicense.txtlicense.txttext/plain1906https://repositorio.ufba.br/bitstream/ri/3782/2/license.txt8f244ebdaef116cf6994392fd1ec1289MD52TEXT26.pdf.txt26.pdf.txtExtracted texttext/plain70048https://repositorio.ufba.br/bitstream/ri/3782/3/26.pdf.txt2e48d71c02666a30e02c5eada708db16MD53ri/37822022-07-05 14:03:20.069oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:20Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Química e farmacologia de quimioterápicos antineoplásicos derivados de plantas
dc.title.alternative.pt_BR.fl_str_mv Química Nova
title Química e farmacologia de quimioterápicos antineoplásicos derivados de plantas
spellingShingle Química e farmacologia de quimioterápicos antineoplásicos derivados de plantas
Brandão, Hugo N.
Plant antineoplasics
Chemotherapic
Cancer
title_short Química e farmacologia de quimioterápicos antineoplásicos derivados de plantas
title_full Química e farmacologia de quimioterápicos antineoplásicos derivados de plantas
title_fullStr Química e farmacologia de quimioterápicos antineoplásicos derivados de plantas
title_full_unstemmed Química e farmacologia de quimioterápicos antineoplásicos derivados de plantas
title_sort Química e farmacologia de quimioterápicos antineoplásicos derivados de plantas
author Brandão, Hugo N.
author_facet Brandão, Hugo N.
David, Juceni Pereira de Lima
Couto, Ricardo David
Nascimento, Jorge A. P.
David, Jorge Mauricio
author_role author
author2 David, Juceni Pereira de Lima
Couto, Ricardo David
Nascimento, Jorge A. P.
David, Jorge Mauricio
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Brandão, Hugo N.
David, Juceni Pereira de Lima
Couto, Ricardo David
Nascimento, Jorge A. P.
David, Jorge Mauricio
Brandão, Hugo N.
David, Juceni Pereira de Lima
Couto, Ricardo David
Nascimento, Jorge A. P.
David, Jorge Mauricio
dc.subject.por.fl_str_mv Plant antineoplasics
Chemotherapic
Cancer
topic Plant antineoplasics
Chemotherapic
Cancer
description p. 1359-1369.
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2011-11-21T11:03:23Z
dc.date.available.fl_str_mv 2011-11-21T11:03:23Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/3782
dc.identifier.issn.none.fl_str_mv 0100-4042
dc.identifier.number.pt_BR.fl_str_mv v. 33, n. 6.
identifier_str_mv 0100-4042
v. 33, n. 6.
url http://www.repositorio.ufba.br/ri/handle/ri/3782
dc.language.iso.fl_str_mv por
language por
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dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
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