Acute hyperglycemia is a reliable outcome predictor in children with severe traumatic brain injury

Detalhes bibliográficos
Autor(a) principal: Melo, José Roberto Tude
Data de Publicação: 2010
Outros Autores: Rocco, Federico Di, Blanot, Stéphane, Laurent-Vannier, Anne, Reis, Rodolfo Casimiro, Baugnon, Thomas, Sainte-Rose, Christian, Olveira-Filho, Jamary, Zerah, Michel, Meyer, Philippe G.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/5646
Resumo: Acesso restrito: Texto completo. p.1559-1565
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spelling Melo, José Roberto TudeRocco, Federico DiBlanot, StéphaneLaurent-Vannier, AnneReis, Rodolfo CasimiroBaugnon, ThomasSainte-Rose, ChristianOlveira-Filho, JamaryZerah, MichelMeyer, Philippe G.Melo, José Roberto TudeRocco, Federico DiBlanot, StéphaneLaurent-Vannier, AnneReis, Rodolfo CasimiroBaugnon, ThomasSainte-Rose, ChristianOlveira-Filho, JamaryZerah, MichelMeyer, Philippe G.2012-04-19T12:18:00Z20100001-6268http://www.repositorio.ufba.br/ri/handle/ri/5646v. 152, n. 9Acesso restrito: Texto completo. p.1559-1565Purpose Hyperglycemia in the acute phase after trauma could adversely affect outcome in children with severe traumatic brain injury (TBI). The goal of this study was to identify the relationship between acute spontaneous hyperglycemia and outcome in children with severe TBI at hospital discharge and 6 months later. Methods A retrospective analysis of blood glucose levels in children with severe TBI at a Pediatric level I Trauma Center, between January 2000 and December 2005. Hyperglycemia was considered for a cut-off value of 11.1 mmol/l (200 mg/dl). Outcome was measured with Glasgow Outcome Scale (GOS) at hospital discharge and at 6 months. A multiple logistic regression analysis, the Student's t test and the χ2 test were done. Results Hyperglycemia was noted within the first 48 h in 34% of the patients. Mortality (70% vs 14%, p<10-5) was more frequent in hyperglycemic children and bad outcome upon hospital discharge in those who remained hyperglycemic during the first 48 h of hospitalization. GOS after 6 months demonstrated that those normoglycemic children had a better outcome (95%) than those who developed hyperglycemia during the first 48 h (83%, p=0.01) after trauma. Conclusion Hyperglycemia could be considered as a marker of brain injury and when present upon admission, could reflect extensive brain damage with frequently associated mortality and bad outcome. The inability to maintain normal blood glucose levels during the first 48 h could be a predictive factor of bad outcome. Avoiding hyperglycemia in the initial phase could be a major issue in children with severe TBI.Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2012-04-19T12:18:00Z No. of bitstreams: 1 __www.springerlink.com_c...463441020qg64w37_fulltext.pdf: 130599 bytes, checksum: e8f6267c14ea1a5ffa2adaff05811afc (MD5)Made available in DSpace on 2012-04-19T12:18:00Z (GMT). No. of bitstreams: 1 __www.springerlink.com_c...463441020qg64w37_fulltext.pdf: 130599 bytes, checksum: e8f6267c14ea1a5ffa2adaff05811afc (MD5) Previous issue date: 2010DOI: 10.1007/s00701-010-0680-zreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAPediatricHead injuryHyperglycemiaPrognosisOutcomeAcute hyperglycemia is a reliable outcome predictor in children with severe traumatic brain injuryACTA NEUROCHIRURGICAinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01enginfo:eu-repo/semantics/openAccessORIGINAL__www.springerlink.com_c...463441020qg64w37_fulltext.pdf__www.springerlink.com_c...463441020qg64w37_fulltext.pdfapplication/pdf130599https://repositorio.ufba.br/bitstream/ri/5646/1/__www.springerlink.com_c...463441020qg64w37_fulltext.pdfe8f6267c14ea1a5ffa2adaff05811afcMD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/5646/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXT__www.springerlink.com_c...463441020qg64w37_fulltext.pdf.txt__www.springerlink.com_c...463441020qg64w37_fulltext.pdf.txtExtracted texttext/plain32394https://repositorio.ufba.br/bitstream/ri/5646/3/__www.springerlink.com_c...463441020qg64w37_fulltext.pdf.txt9aea2aa985d28e328906733b9481bcadMD53ri/56462022-07-05 14:03:21.9oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:21Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Acute hyperglycemia is a reliable outcome predictor in children with severe traumatic brain injury
dc.title.alternative.pt_BR.fl_str_mv ACTA NEUROCHIRURGICA
title Acute hyperglycemia is a reliable outcome predictor in children with severe traumatic brain injury
spellingShingle Acute hyperglycemia is a reliable outcome predictor in children with severe traumatic brain injury
Melo, José Roberto Tude
Pediatric
Head injury
Hyperglycemia
Prognosis
Outcome
title_short Acute hyperglycemia is a reliable outcome predictor in children with severe traumatic brain injury
title_full Acute hyperglycemia is a reliable outcome predictor in children with severe traumatic brain injury
title_fullStr Acute hyperglycemia is a reliable outcome predictor in children with severe traumatic brain injury
title_full_unstemmed Acute hyperglycemia is a reliable outcome predictor in children with severe traumatic brain injury
title_sort Acute hyperglycemia is a reliable outcome predictor in children with severe traumatic brain injury
author Melo, José Roberto Tude
author_facet Melo, José Roberto Tude
Rocco, Federico Di
Blanot, Stéphane
Laurent-Vannier, Anne
Reis, Rodolfo Casimiro
Baugnon, Thomas
Sainte-Rose, Christian
Olveira-Filho, Jamary
Zerah, Michel
Meyer, Philippe G.
author_role author
author2 Rocco, Federico Di
Blanot, Stéphane
Laurent-Vannier, Anne
Reis, Rodolfo Casimiro
Baugnon, Thomas
Sainte-Rose, Christian
Olveira-Filho, Jamary
Zerah, Michel
Meyer, Philippe G.
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Melo, José Roberto Tude
Rocco, Federico Di
Blanot, Stéphane
Laurent-Vannier, Anne
Reis, Rodolfo Casimiro
Baugnon, Thomas
Sainte-Rose, Christian
Olveira-Filho, Jamary
Zerah, Michel
Meyer, Philippe G.
Melo, José Roberto Tude
Rocco, Federico Di
Blanot, Stéphane
Laurent-Vannier, Anne
Reis, Rodolfo Casimiro
Baugnon, Thomas
Sainte-Rose, Christian
Olveira-Filho, Jamary
Zerah, Michel
Meyer, Philippe G.
dc.subject.por.fl_str_mv Pediatric
Head injury
Hyperglycemia
Prognosis
Outcome
topic Pediatric
Head injury
Hyperglycemia
Prognosis
Outcome
description Acesso restrito: Texto completo. p.1559-1565
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2012-04-19T12:18:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/5646
dc.identifier.issn.none.fl_str_mv 0001-6268
dc.identifier.number.pt_BR.fl_str_mv v. 152, n. 9
identifier_str_mv 0001-6268
v. 152, n. 9
url http://www.repositorio.ufba.br/ri/handle/ri/5646
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.source.pt_BR.fl_str_mv DOI: 10.1007/s00701-010-0680-z
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
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