Gestational Diabetes Mellitus Diagnosed With a 2-h 75-g Oral Glucose Tolerance Test and Adverse Pregnancy Outcomes

Detalhes bibliográficos
Autor(a) principal: Schmidt, Maria Inês
Data de Publicação: 2001
Outros Autores: Duncan, Bruce Bartholow, Reichelt, Angela J., Branchtein, Leandro, Matos, Maria C., Forti, Adriana Costa e, Spichler, Ethel R., Pousada, Judith Maria Dias Carreiro, Teixeira, Margareth M., Yamashita, Tsuyoshi
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/18107
Resumo: Texto completo: acesso restrito. p. 1151-1155
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spelling Schmidt, Maria InêsDuncan, Bruce BartholowReichelt, Angela J.Branchtein, LeandroMatos, Maria C.Forti, Adriana Costa eSpichler, Ethel R.Pousada, Judith Maria Dias CarreiroTeixeira, Margareth M.Yamashita, Tsuyoshi2015-10-13T12:25:00Z20010149-5992http://repositorio.ufba.br/ri/handle/ri/18107v. 24, n. 7Texto completo: acesso restrito. p. 1151-1155OBJECTIVE—To evaluate American Diabetes Association (ADA) and World Health Organization (WHO) diagnostic criteria for gestational diabetes mellitus (GDM) against pregnancy outcomes. RESEARCH DESIGN AND METHODS—This cohort study consecutively enrolled Brazilian adult women attending general prenatal clinics. All women were requested to undertake a standardized 2-h 75-g oral glucose tolerance test (OGTT) between their estimated 24th and 28th gestational weeks and were then followed to delivery. New ADA criteria for GDM require two plasma glucose values ≥5.3 mmol/l (fasting), ≥10 mmol/l (1 h), and ≥8.6 mmol/l (2 h). WHO criteria require a plasma glucose ≥7.0 mmol/l (fasting) or ≥7.8 mmol/l (2 h). Individuals with hyperglycemia indicative of diabetes outside of pregnancy were excluded. RESULTS—Among the 4,977 women studied, 2.4% (95% CI 2.0–2.9) presented with GDM by ADA criteria and 7.2% (6.5–7.9) by WHO criteria. After adjustment for the effects of age, obesity, and other risk factors, GDM by ADA criteria predicted an increased risk of macrosomia (RR 1.29, 95% CI 0.73–2.18), preeclampsia (2.28, 1.22–4.16), and perinatal death (3.10, 1.42–6.47). Similarly, GDM by WHO criteria predicted increased risk for macrosomia (1.45, 1.06–1.95), preeclampsia (1.94, 1.22–3.03), and perinatal death (1.59, 0.86–2.90). Of women positive by WHO criteria, 260 (73%) were negative by ADA criteria. Conversely, 22 (18%) women positive by ADA criteria were negative by WHO criteria. CONCLUSIONS—GDM based on a 2-h 75-g OGTT defined by either WHO or ADA criteria predicts adverse pregnancy outcomes.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-01-31T13:22:15Z No. of bitstreams: 1 Judith M.D.C. Pousada.pdf: 105835 bytes, checksum: 043c7a42a4639300650718ff39f9ee04 (MD5)Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2015-10-13T12:25:00Z (GMT) No. of bitstreams: 1 Judith M.D.C. Pousada.pdf: 105835 bytes, checksum: 043c7a42a4639300650718ff39f9ee04 (MD5)Made available in DSpace on 2015-10-13T12:25:00Z (GMT). No. of bitstreams: 1 Judith M.D.C. Pousada.pdf: 105835 bytes, checksum: 043c7a42a4639300650718ff39f9ee04 (MD5) Previous issue date: 2001http://dx.doi.org/ 10.2337/diacare.24.7.1151reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBADiabetes MellitusGlucoseDiabetes, GestationalHypertensionGestational Diabetes Mellitus Diagnosed With a 2-h 75-g Oral Glucose Tolerance Test and Adverse Pregnancy OutcomesDiabetes Careinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALJudith M.D.C. Pousada.pdfJudith M.D.C. Pousada.pdfapplication/pdf105835https://repositorio.ufba.br/bitstream/ri/18107/1/Judith%20M.D.C.%20Pousada.pdf043c7a42a4639300650718ff39f9ee04MD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/18107/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXTJudith M.D.C. Pousada.pdf.txtJudith M.D.C. 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dc.title.pt_BR.fl_str_mv Gestational Diabetes Mellitus Diagnosed With a 2-h 75-g Oral Glucose Tolerance Test and Adverse Pregnancy Outcomes
dc.title.alternative.pt_BR.fl_str_mv Diabetes Care
title Gestational Diabetes Mellitus Diagnosed With a 2-h 75-g Oral Glucose Tolerance Test and Adverse Pregnancy Outcomes
spellingShingle Gestational Diabetes Mellitus Diagnosed With a 2-h 75-g Oral Glucose Tolerance Test and Adverse Pregnancy Outcomes
Schmidt, Maria Inês
Diabetes Mellitus
Glucose
Diabetes, Gestational
Hypertension
title_short Gestational Diabetes Mellitus Diagnosed With a 2-h 75-g Oral Glucose Tolerance Test and Adverse Pregnancy Outcomes
title_full Gestational Diabetes Mellitus Diagnosed With a 2-h 75-g Oral Glucose Tolerance Test and Adverse Pregnancy Outcomes
title_fullStr Gestational Diabetes Mellitus Diagnosed With a 2-h 75-g Oral Glucose Tolerance Test and Adverse Pregnancy Outcomes
title_full_unstemmed Gestational Diabetes Mellitus Diagnosed With a 2-h 75-g Oral Glucose Tolerance Test and Adverse Pregnancy Outcomes
title_sort Gestational Diabetes Mellitus Diagnosed With a 2-h 75-g Oral Glucose Tolerance Test and Adverse Pregnancy Outcomes
author Schmidt, Maria Inês
author_facet Schmidt, Maria Inês
Duncan, Bruce Bartholow
Reichelt, Angela J.
Branchtein, Leandro
Matos, Maria C.
Forti, Adriana Costa e
Spichler, Ethel R.
Pousada, Judith Maria Dias Carreiro
Teixeira, Margareth M.
Yamashita, Tsuyoshi
author_role author
author2 Duncan, Bruce Bartholow
Reichelt, Angela J.
Branchtein, Leandro
Matos, Maria C.
Forti, Adriana Costa e
Spichler, Ethel R.
Pousada, Judith Maria Dias Carreiro
Teixeira, Margareth M.
Yamashita, Tsuyoshi
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Schmidt, Maria Inês
Duncan, Bruce Bartholow
Reichelt, Angela J.
Branchtein, Leandro
Matos, Maria C.
Forti, Adriana Costa e
Spichler, Ethel R.
Pousada, Judith Maria Dias Carreiro
Teixeira, Margareth M.
Yamashita, Tsuyoshi
dc.subject.por.fl_str_mv Diabetes Mellitus
Glucose
Diabetes, Gestational
Hypertension
topic Diabetes Mellitus
Glucose
Diabetes, Gestational
Hypertension
description Texto completo: acesso restrito. p. 1151-1155
publishDate 2001
dc.date.issued.fl_str_mv 2001
dc.date.accessioned.fl_str_mv 2015-10-13T12:25:00Z
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dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/18107
dc.identifier.issn.none.fl_str_mv 0149-5992
dc.identifier.number.pt_BR.fl_str_mv v. 24, n. 7
identifier_str_mv 0149-5992
v. 24, n. 7
url http://repositorio.ufba.br/ri/handle/ri/18107
dc.language.iso.fl_str_mv eng
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