Amount of physical activity necessary for a normal level of high-sensitivity C-reactive protein in ELSA-Brasil: a cross-sectional study
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://repositorio.ufba.br/ri/handle/ri/34464 |
Resumo: | BACKGROUND:Studies have shown that physical activity levels can be inversely associated with high-sensitivity C-reactive protein (hs-CRP) levels. However, the amount of physical activity required to maintain normal hs-CRP levels is still a matter for speculation. OBJECTIVE: To identify the amount of physical activity necessary to discriminate the hs-CRP levels in adults. DESIGN AND SETTING: Cross-sectional study at six teaching and research institutions.METHODS: The study sample comprised 10,231 adults aged 35 to 74 years who were participants in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Receiver operating characteristic (ROC) curves were constructed to compare the amount of physical activity in two domains (leisure time and commuting) with hs-CRP levels. The sensitivity and specificity were calculated to identify the best cutoff for physical activity level that would be needed to maintain normal levels of hs-CRP (< 3 mg/l).c. RESULTS: The area under the ROC curve was only statistically significant for discriminating normal levels of hs-CRP according to the amount of physical activity when the two study domains were added together. The accumulated physical activity level of 200 minutes/week was the best cutoff for discriminating normal levels of hs-CRP in adults of both sex. CONCLUSIONS: Physical activity in the leisure-time and commuting domains together, of duration 200 minutes /week, was associated with normal hs-CRP values. |
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Queiroz, Ciro OliveiraPitanga, FranciscoLotufo, Paulo AndradeMolina, Maria Del Carmen BisiAquino, Estela Maria Motta Lima Leão deAlmeida, Maria Conceição Chagas2021-11-04T19:11:15Z2021-11-04T19:11:15Z2020-021806-9460http://repositorio.ufba.br/ri/handle/ri/34464São Paulo Med. J., v.138, n.1, p.1-8BACKGROUND:Studies have shown that physical activity levels can be inversely associated with high-sensitivity C-reactive protein (hs-CRP) levels. However, the amount of physical activity required to maintain normal hs-CRP levels is still a matter for speculation. OBJECTIVE: To identify the amount of physical activity necessary to discriminate the hs-CRP levels in adults. DESIGN AND SETTING: Cross-sectional study at six teaching and research institutions.METHODS: The study sample comprised 10,231 adults aged 35 to 74 years who were participants in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Receiver operating characteristic (ROC) curves were constructed to compare the amount of physical activity in two domains (leisure time and commuting) with hs-CRP levels. The sensitivity and specificity were calculated to identify the best cutoff for physical activity level that would be needed to maintain normal levels of hs-CRP (< 3 mg/l).c. RESULTS: The area under the ROC curve was only statistically significant for discriminating normal levels of hs-CRP according to the amount of physical activity when the two study domains were added together. The accumulated physical activity level of 200 minutes/week was the best cutoff for discriminating normal levels of hs-CRP in adults of both sex. CONCLUSIONS: Physical activity in the leisure-time and commuting domains together, of duration 200 minutes /week, was associated with normal hs-CRP values.Submitted by Maria Creuza Silva (mariakreuza@yahoo.com.br) on 2021-11-04T18:39:23Z No. of bitstreams: 1 Amount of physical activity necessary for a normal level.pdf: 258138 bytes, checksum: 8f4c99a9743e21fb0e1c77ecfd36efc9 (MD5)Approved for entry into archive by Maria Creuza Silva (mariakreuza@yahoo.com.br) on 2021-11-04T19:11:15Z (GMT) No. of bitstreams: 1 Amount of physical activity necessary for a normal level.pdf: 258138 bytes, checksum: 8f4c99a9743e21fb0e1c77ecfd36efc9 (MD5)Made available in DSpace on 2021-11-04T19:11:15Z (GMT). No. of bitstreams: 1 Amount of physical activity necessary for a normal level.pdf: 258138 bytes, checksum: 8f4c99a9743e21fb0e1c77ecfd36efc9 (MD5) Previous issue date: 2020-02São PauloAssociação Paulista de Medicina - APMBrasilhttps://www.scielo.br/j/spmj/a/V43dQmKPGMdHT5xybtRWBdm/?lang=enreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAMotor ActivityRisk FactorsROC CurveCardiovascular DiseasesInflammationAmount of physical activity necessary for a normal level of high-sensitivity C-reactive protein in ELSA-Brasil: a cross-sectional studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessengORIGINALAmount of physical activity necessary for a normal level.pdfAmount of physical activity necessary for a normal level.pdfapplication/pdf258138https://repositorio.ufba.br/bitstream/ri/34464/1/Amount%20of%20physical%20activity%20necessary%20for%20a%20normal%20level.pdf8f4c99a9743e21fb0e1c77ecfd36efc9MD51LICENSElicense.txtlicense.txttext/plain1582https://repositorio.ufba.br/bitstream/ri/34464/2/license.txt907e2b7d511fb2c3e42dbdd41a6197c6MD52TEXTAmount of physical activity necessary for a normal level.pdf.txtAmount of physical activity necessary for a normal level.pdf.txtExtracted texttext/plain40200https://repositorio.ufba.br/bitstream/ri/34464/3/Amount%20of%20physical%20activity%20necessary%20for%20a%20normal%20level.pdf.txtece2e28abe65e0e85450c9cf567919e1MD53ri/344642022-03-23 20:08:32.335oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-03-23T23:08:32Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
dc.title.pt_BR.fl_str_mv |
Amount of physical activity necessary for a normal level of high-sensitivity C-reactive protein in ELSA-Brasil: a cross-sectional study |
title |
Amount of physical activity necessary for a normal level of high-sensitivity C-reactive protein in ELSA-Brasil: a cross-sectional study |
spellingShingle |
Amount of physical activity necessary for a normal level of high-sensitivity C-reactive protein in ELSA-Brasil: a cross-sectional study Queiroz, Ciro Oliveira Motor Activity Risk Factors ROC Curve Cardiovascular Diseases Inflammation |
title_short |
Amount of physical activity necessary for a normal level of high-sensitivity C-reactive protein in ELSA-Brasil: a cross-sectional study |
title_full |
Amount of physical activity necessary for a normal level of high-sensitivity C-reactive protein in ELSA-Brasil: a cross-sectional study |
title_fullStr |
Amount of physical activity necessary for a normal level of high-sensitivity C-reactive protein in ELSA-Brasil: a cross-sectional study |
title_full_unstemmed |
Amount of physical activity necessary for a normal level of high-sensitivity C-reactive protein in ELSA-Brasil: a cross-sectional study |
title_sort |
Amount of physical activity necessary for a normal level of high-sensitivity C-reactive protein in ELSA-Brasil: a cross-sectional study |
author |
Queiroz, Ciro Oliveira |
author_facet |
Queiroz, Ciro Oliveira Pitanga, Francisco Lotufo, Paulo Andrade Molina, Maria Del Carmen Bisi Aquino, Estela Maria Motta Lima Leão de Almeida, Maria Conceição Chagas |
author_role |
author |
author2 |
Pitanga, Francisco Lotufo, Paulo Andrade Molina, Maria Del Carmen Bisi Aquino, Estela Maria Motta Lima Leão de Almeida, Maria Conceição Chagas |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Queiroz, Ciro Oliveira Pitanga, Francisco Lotufo, Paulo Andrade Molina, Maria Del Carmen Bisi Aquino, Estela Maria Motta Lima Leão de Almeida, Maria Conceição Chagas |
dc.subject.por.fl_str_mv |
Motor Activity Risk Factors ROC Curve Cardiovascular Diseases Inflammation |
topic |
Motor Activity Risk Factors ROC Curve Cardiovascular Diseases Inflammation |
description |
BACKGROUND:Studies have shown that physical activity levels can be inversely associated with high-sensitivity C-reactive protein (hs-CRP) levels. However, the amount of physical activity required to maintain normal hs-CRP levels is still a matter for speculation. OBJECTIVE: To identify the amount of physical activity necessary to discriminate the hs-CRP levels in adults. DESIGN AND SETTING: Cross-sectional study at six teaching and research institutions.METHODS: The study sample comprised 10,231 adults aged 35 to 74 years who were participants in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Receiver operating characteristic (ROC) curves were constructed to compare the amount of physical activity in two domains (leisure time and commuting) with hs-CRP levels. The sensitivity and specificity were calculated to identify the best cutoff for physical activity level that would be needed to maintain normal levels of hs-CRP (< 3 mg/l).c. RESULTS: The area under the ROC curve was only statistically significant for discriminating normal levels of hs-CRP according to the amount of physical activity when the two study domains were added together. The accumulated physical activity level of 200 minutes/week was the best cutoff for discriminating normal levels of hs-CRP in adults of both sex. CONCLUSIONS: Physical activity in the leisure-time and commuting domains together, of duration 200 minutes /week, was associated with normal hs-CRP values. |
publishDate |
2020 |
dc.date.issued.fl_str_mv |
2020-02 |
dc.date.accessioned.fl_str_mv |
2021-11-04T19:11:15Z |
dc.date.available.fl_str_mv |
2021-11-04T19:11:15Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://repositorio.ufba.br/ri/handle/ri/34464 |
dc.identifier.issn.none.fl_str_mv |
1806-9460 |
dc.identifier.number.pt_BR.fl_str_mv |
São Paulo Med. J., v.138, n.1, p.1-8 |
identifier_str_mv |
1806-9460 São Paulo Med. J., v.138, n.1, p.1-8 |
url |
http://repositorio.ufba.br/ri/handle/ri/34464 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
dc.publisher.none.fl_str_mv |
Associação Paulista de Medicina - APM |
dc.publisher.country.fl_str_mv |
Brasil |
publisher.none.fl_str_mv |
Associação Paulista de Medicina - APM |
dc.source.pt_BR.fl_str_mv |
https://www.scielo.br/j/spmj/a/V43dQmKPGMdHT5xybtRWBdm/?lang=en |
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reponame:Repositório Institucional da UFBA instname:Universidade Federal da Bahia (UFBA) instacron:UFBA |
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Universidade Federal da Bahia (UFBA) |
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UFBA |
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UFBA |
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Repositório Institucional da UFBA |
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Repositório Institucional da UFBA |
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