Biodemes and zymodemes of trypanosoma cruzi strains: correlations with clinical data and experimental pathology

Detalhes bibliográficos
Autor(a) principal: Andrade, Sonia Gumes
Data de Publicação: 1997
Outros Autores: Magalhães, Juracy B.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/13466
Resumo: p. 27-35
id UFBA-2_14783dd5d9753873ac7fe7a049c3aba5
oai_identifier_str oai:repositorio.ufba.br:ri/13466
network_acronym_str UFBA-2
network_name_str Repositório Institucional da UFBA
repository_id_str 1932
spelling Andrade, Sonia GumesMagalhães, Juracy B.Andrade, Sonia GumesMagalhães, Juracy B.2013-11-01T11:43:36Z2013-11-01T11:43:36Z19970037-8682http://repositorio.ufba.br/ri/handle/ri/13466v. 30, n. 1p. 27-35With the objective of establishing biological and biochemical characteristics of a significant number of Trypanosoma cruzi strains from different geographical areas, 138 strains isolated from naturally infected humans, triatomine or vertebrate hosts were studied; 120 were isolated from different areas of Brazil and 18 from other South and Central American countries. Inocula from triatomine or culture forms were injected into suckling Swiss mice, followed by passages into mice 10 to 12 g. Biological characters and histopathological study permitted the inclusion of the strains into three Types or biodemes: I, II, III. Isoenzymic analysis confirmed a correspondence between the biodemes and zymodemes : Type I and Z2b, Type II and Z2, Type III and Z1. Results showed the ubiquitary distribution of the several types of strains. The predominance of the same Type and zymodeme in one geographical area was confirmed : Type II strains among the human cases from eastern Bahia and east of Goiás; Type III strains from humans of north Brazil and Central America and from silvatic vectors or vertebrates from other geographical areas. The biological types of strains correlate with different histopathological lesions considering cardiac involvement and neuronal lesions. These findings suggest that the biological behavior together with isoenzymes patterns and pathological pictures in the vertebrate host can be an important tool for establishing correlations between strains behavior and clinico-pathological manifestations of Chagas' disease in different geographical areas.Submitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2013-09-11T17:59:55Z No. of bitstreams: 1 111111111.pdf: 162703 bytes, checksum: 2735bc7a4a5522cd3d4293b7af9b32f9 (MD5)Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2013-11-01T11:43:35Z (GMT) No. of bitstreams: 1 111111111.pdf: 162703 bytes, checksum: 2735bc7a4a5522cd3d4293b7af9b32f9 (MD5)Made available in DSpace on 2013-11-01T11:43:36Z (GMT). No. of bitstreams: 1 111111111.pdf: 162703 bytes, checksum: 2735bc7a4a5522cd3d4293b7af9b32f9 (MD5) Previous issue date: 1997UberabaRevista da Sociedade Brasileira de Medicina Tropicalhttp://dx.doi.org/10.1590/S0037-86821997000100006reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBATrypanosoma cruzi strainsGeographical distributionBiodemesZymodemesPathology of Chagas'diseaseBiodemes and zymodemes of trypanosoma cruzi strains: correlations with clinical data and experimental pathologyRevista da Sociedade Brasileira de Medicina Tropicalinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleenginfo:eu-repo/semantics/openAccessLICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/13466/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52ORIGINAL111111111.pdf111111111.pdfapplication/pdf162703https://repositorio.ufba.br/bitstream/ri/13466/1/111111111.pdf2735bc7a4a5522cd3d4293b7af9b32f9MD51TEXT111111111.pdf.txt111111111.pdf.txtExtracted texttext/plain35510https://repositorio.ufba.br/bitstream/ri/13466/3/111111111.pdf.txtf5aa62406294da3a8fb8e5f1fdf63d20MD53ri/134662022-07-05 14:03:43.83oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:43Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Biodemes and zymodemes of trypanosoma cruzi strains: correlations with clinical data and experimental pathology
dc.title.alternative.pt_BR.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical
title Biodemes and zymodemes of trypanosoma cruzi strains: correlations with clinical data and experimental pathology
spellingShingle Biodemes and zymodemes of trypanosoma cruzi strains: correlations with clinical data and experimental pathology
Andrade, Sonia Gumes
Trypanosoma cruzi strains
Geographical distribution
Biodemes
Zymodemes
Pathology of Chagas'disease
title_short Biodemes and zymodemes of trypanosoma cruzi strains: correlations with clinical data and experimental pathology
title_full Biodemes and zymodemes of trypanosoma cruzi strains: correlations with clinical data and experimental pathology
title_fullStr Biodemes and zymodemes of trypanosoma cruzi strains: correlations with clinical data and experimental pathology
title_full_unstemmed Biodemes and zymodemes of trypanosoma cruzi strains: correlations with clinical data and experimental pathology
title_sort Biodemes and zymodemes of trypanosoma cruzi strains: correlations with clinical data and experimental pathology
author Andrade, Sonia Gumes
author_facet Andrade, Sonia Gumes
Magalhães, Juracy B.
author_role author
author2 Magalhães, Juracy B.
author2_role author
dc.contributor.author.fl_str_mv Andrade, Sonia Gumes
Magalhães, Juracy B.
Andrade, Sonia Gumes
Magalhães, Juracy B.
dc.subject.por.fl_str_mv Trypanosoma cruzi strains
Geographical distribution
Biodemes
Zymodemes
Pathology of Chagas'disease
topic Trypanosoma cruzi strains
Geographical distribution
Biodemes
Zymodemes
Pathology of Chagas'disease
description p. 27-35
publishDate 1997
dc.date.issued.fl_str_mv 1997
dc.date.accessioned.fl_str_mv 2013-11-01T11:43:36Z
dc.date.available.fl_str_mv 2013-11-01T11:43:36Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/13466
dc.identifier.issn.none.fl_str_mv 0037-8682
dc.identifier.number.pt_BR.fl_str_mv v. 30, n. 1
identifier_str_mv 0037-8682
v. 30, n. 1
url http://repositorio.ufba.br/ri/handle/ri/13466
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical
publisher.none.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1590/S0037-86821997000100006
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
bitstream.url.fl_str_mv https://repositorio.ufba.br/bitstream/ri/13466/2/license.txt
https://repositorio.ufba.br/bitstream/ri/13466/1/111111111.pdf
https://repositorio.ufba.br/bitstream/ri/13466/3/111111111.pdf.txt
bitstream.checksum.fl_str_mv 1b89a9a0548218172d7c829f87a0eab9
2735bc7a4a5522cd3d4293b7af9b32f9
f5aa62406294da3a8fb8e5f1fdf63d20
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)
repository.mail.fl_str_mv
_version_ 1798057637902811136

Registros relacionados