Application of analytical methods for the structural characterization and purity assessment of N,N-dimethyltryptamine, a potent psychedelic agent isolated from Mimosa tenuiflora inner barks
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://repositorio.ufba.br/ri/handle/ri/15004 |
Resumo: | Texto completo: acesso restrito. p. 78–83 |
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Gaujac, AlainMartinez, Sabrina TeixeiraGomes, Arão AraújoAndrade, Sandro José dePinto, Angelo da CunhaDavid, Jorge MauricioNavickiene, SandroAndrade, Jailson Bittencourt deGaujac, AlainMartinez, Sabrina TeixeiraGomes, Arão AraújoAndrade, Sandro José dePinto, Angelo da CunhaDavid, Jorge MauricioNavickiene, SandroAndrade, Jailson Bittencourt de2014-05-20T15:48:21Z20130026-265Xhttp://repositorio.ufba.br/ri/handle/ri/15004v. 109Texto completo: acesso restrito. p. 78–83N,N-dimethyltryptamine (DMT) is a psychoactive indole alkaloid present in beverages consumed in religious ceremonies and in neo-shamanic rituals all around the world. It is a substance banned in most countries, which makes its acquisition difficult. In Brazil, a beverage rich in DMT named ayahuasca is legally consumed in a religious context. On the other hand, DMT is a controlled drug, enforced by the Brazilian National Health Surveillance Agency (Agência Nacional de Vigilância Sanitária). The present study describes a simple and fast method to obtain N,N-dimethyltryptamine (DMT) from inner barks of Mimosa tenuiflora for the purpose of using it as a chromatographic analytical standard. Fourier transform infrared spectroscopy (FTIR), single and tandem stage mass spectrometry (MS), nuclear magnetic resonance spectroscopy (1H and 13C NMR) and melting point measurements were performed for the structural characterization of N,N-dimethyltryptamine. The results obtained were in agreement with previous literature reports. The purity of the compound (> 95%) was determined using ultraviolet (UV) absorption spectrometry with a tryptamine analytical standard.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-05-20T15:48:21Z No. of bitstreams: 1 1-s2.0-S0026265X12000926-main.pdf: 672034 bytes, checksum: 5da1fe5884b21dac691ffe6f65740c7e (MD5)Made available in DSpace on 2014-05-20T15:48:21Z (GMT). No. of bitstreams: 1 1-s2.0-S0026265X12000926-main.pdf: 672034 bytes, checksum: 5da1fe5884b21dac691ffe6f65740c7e (MD5) Previous issue date: 2013http://dx.doi.org/10.1016/j.microc.2012.03.033reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAN,N-dimethyltryptamineMimosa tenuifloraStructural characterizationPurity assessmentAnalytical techniquesApplication of analytical methods for the structural characterization and purity assessment of N,N-dimethyltryptamine, a potent psychedelic agent isolated from Mimosa tenuiflora inner barksMicrochemical Journalinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengLICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/15004/2/license.txt0d4b811ef71182510d2015daa7c8a900MD52ORIGINAL1-s2.0-S0026265X12000926-main.pdf1-s2.0-S0026265X12000926-main.pdfapplication/pdf672034https://repositorio.ufba.br/bitstream/ri/15004/1/1-s2.0-S0026265X12000926-main.pdf5da1fe5884b21dac691ffe6f65740c7eMD51TEXT1-s2.0-S0026265X12000926-main.pdf.txt1-s2.0-S0026265X12000926-main.pdf.txtExtracted texttext/plain24750https://repositorio.ufba.br/bitstream/ri/15004/3/1-s2.0-S0026265X12000926-main.pdf.txtd3aec32f19f0ce65a1731189d2bfd7a5MD53ri/150042022-07-05 14:03:51.369oai:repositorio.ufba.br:ri/15004VGVybW8gZGUgTGljZW4/YSwgbj9vIGV4Y2x1c2l2bywgcGFyYSBvIGRlcD9zaXRvIG5vIFJlcG9zaXQ/cmlvIEluc3RpdHVjaW9uYWwgZGEgVUZCQS4KCiBQZWxvIHByb2Nlc3NvIGRlIHN1Ym1pc3M/byBkZSBkb2N1bWVudG9zLCBvIGF1dG9yIG91IHNldSByZXByZXNlbnRhbnRlIGxlZ2FsLCBhbyBhY2VpdGFyIAplc3NlIHRlcm1vIGRlIGxpY2VuP2EsIGNvbmNlZGUgYW8gUmVwb3NpdD9yaW8gSW5zdGl0dWNpb25hbCBkYSBVbml2ZXJzaWRhZGUgRmVkZXJhbCBkYSBCYWhpYSAKbyBkaXJlaXRvIGRlIG1hbnRlciB1bWEgYz9waWEgZW0gc2V1IHJlcG9zaXQ/cmlvIGNvbSBhIGZpbmFsaWRhZGUsIHByaW1laXJhLCBkZSBwcmVzZXJ2YT8/by4gCkVzc2VzIHRlcm1vcywgbj9vIGV4Y2x1c2l2b3MsIG1hbnQ/bSBvcyBkaXJlaXRvcyBkZSBhdXRvci9jb3B5cmlnaHQsIG1hcyBlbnRlbmRlIG8gZG9jdW1lbnRvIApjb21vIHBhcnRlIGRvIGFjZXJ2byBpbnRlbGVjdHVhbCBkZXNzYSBVbml2ZXJzaWRhZGUuCgogUGFyYSBvcyBkb2N1bWVudG9zIHB1YmxpY2Fkb3MgY29tIHJlcGFzc2UgZGUgZGlyZWl0b3MgZGUgZGlzdHJpYnVpPz9vLCBlc3NlIHRlcm1vIGRlIGxpY2VuP2EgCmVudGVuZGUgcXVlOgoKIE1hbnRlbmRvIG9zIGRpcmVpdG9zIGF1dG9yYWlzLCByZXBhc3NhZG9zIGEgdGVyY2Vpcm9zLCBlbSBjYXNvIGRlIHB1YmxpY2E/P2VzLCBvIHJlcG9zaXQ/cmlvCnBvZGUgcmVzdHJpbmdpciBvIGFjZXNzbyBhbyB0ZXh0byBpbnRlZ3JhbCwgbWFzIGxpYmVyYSBhcyBpbmZvcm1hPz9lcyBzb2JyZSBvIGRvY3VtZW50bwooTWV0YWRhZG9zIGVzY3JpdGl2b3MpLgoKIERlc3RhIGZvcm1hLCBhdGVuZGVuZG8gYW9zIGFuc2Vpb3MgZGVzc2EgdW5pdmVyc2lkYWRlIGVtIG1hbnRlciBzdWEgcHJvZHU/P28gY2llbnQ/ZmljYSBjb20gCmFzIHJlc3RyaT8/ZXMgaW1wb3N0YXMgcGVsb3MgZWRpdG9yZXMgZGUgcGVyaT9kaWNvcy4KCiBQYXJhIGFzIHB1YmxpY2E/P2VzIHNlbSBpbmljaWF0aXZhcyBxdWUgc2VndWVtIGEgcG9sP3RpY2EgZGUgQWNlc3NvIEFiZXJ0bywgb3MgZGVwP3NpdG9zIApjb21wdWxzP3Jpb3MgbmVzc2UgcmVwb3NpdD9yaW8gbWFudD9tIG9zIGRpcmVpdG9zIGF1dG9yYWlzLCBtYXMgbWFudD9tIGFjZXNzbyBpcnJlc3RyaXRvIAphbyBtZXRhZGFkb3MgZSB0ZXh0byBjb21wbGV0by4gQXNzaW0sIGEgYWNlaXRhPz9vIGRlc3NlIHRlcm1vIG4/byBuZWNlc3NpdGEgZGUgY29uc2VudGltZW50bwogcG9yIHBhcnRlIGRlIGF1dG9yZXMvZGV0ZW50b3JlcyBkb3MgZGlyZWl0b3MsIHBvciBlc3RhcmVtIGVtIGluaWNpYXRpdmFzIGRlIGFjZXNzbyBhYmVydG8uCg==Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:51Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
dc.title.pt_BR.fl_str_mv |
Application of analytical methods for the structural characterization and purity assessment of N,N-dimethyltryptamine, a potent psychedelic agent isolated from Mimosa tenuiflora inner barks |
dc.title.alternative.pt_BR.fl_str_mv |
Microchemical Journal |
title |
Application of analytical methods for the structural characterization and purity assessment of N,N-dimethyltryptamine, a potent psychedelic agent isolated from Mimosa tenuiflora inner barks |
spellingShingle |
Application of analytical methods for the structural characterization and purity assessment of N,N-dimethyltryptamine, a potent psychedelic agent isolated from Mimosa tenuiflora inner barks Gaujac, Alain N,N-dimethyltryptamine Mimosa tenuiflora Structural characterization Purity assessment Analytical techniques |
title_short |
Application of analytical methods for the structural characterization and purity assessment of N,N-dimethyltryptamine, a potent psychedelic agent isolated from Mimosa tenuiflora inner barks |
title_full |
Application of analytical methods for the structural characterization and purity assessment of N,N-dimethyltryptamine, a potent psychedelic agent isolated from Mimosa tenuiflora inner barks |
title_fullStr |
Application of analytical methods for the structural characterization and purity assessment of N,N-dimethyltryptamine, a potent psychedelic agent isolated from Mimosa tenuiflora inner barks |
title_full_unstemmed |
Application of analytical methods for the structural characterization and purity assessment of N,N-dimethyltryptamine, a potent psychedelic agent isolated from Mimosa tenuiflora inner barks |
title_sort |
Application of analytical methods for the structural characterization and purity assessment of N,N-dimethyltryptamine, a potent psychedelic agent isolated from Mimosa tenuiflora inner barks |
author |
Gaujac, Alain |
author_facet |
Gaujac, Alain Martinez, Sabrina Teixeira Gomes, Arão Araújo Andrade, Sandro José de Pinto, Angelo da Cunha David, Jorge Mauricio Navickiene, Sandro Andrade, Jailson Bittencourt de |
author_role |
author |
author2 |
Martinez, Sabrina Teixeira Gomes, Arão Araújo Andrade, Sandro José de Pinto, Angelo da Cunha David, Jorge Mauricio Navickiene, Sandro Andrade, Jailson Bittencourt de |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Gaujac, Alain Martinez, Sabrina Teixeira Gomes, Arão Araújo Andrade, Sandro José de Pinto, Angelo da Cunha David, Jorge Mauricio Navickiene, Sandro Andrade, Jailson Bittencourt de Gaujac, Alain Martinez, Sabrina Teixeira Gomes, Arão Araújo Andrade, Sandro José de Pinto, Angelo da Cunha David, Jorge Mauricio Navickiene, Sandro Andrade, Jailson Bittencourt de |
dc.subject.por.fl_str_mv |
N,N-dimethyltryptamine Mimosa tenuiflora Structural characterization Purity assessment Analytical techniques |
topic |
N,N-dimethyltryptamine Mimosa tenuiflora Structural characterization Purity assessment Analytical techniques |
description |
Texto completo: acesso restrito. p. 78–83 |
publishDate |
2013 |
dc.date.issued.fl_str_mv |
2013 |
dc.date.accessioned.fl_str_mv |
2014-05-20T15:48:21Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://repositorio.ufba.br/ri/handle/ri/15004 |
dc.identifier.issn.none.fl_str_mv |
0026-265X |
dc.identifier.number.pt_BR.fl_str_mv |
v. 109 |
identifier_str_mv |
0026-265X v. 109 |
url |
http://repositorio.ufba.br/ri/handle/ri/15004 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
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http://dx.doi.org/10.1016/j.microc.2012.03.033 |
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reponame:Repositório Institucional da UFBA instname:Universidade Federal da Bahia (UFBA) instacron:UFBA |
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Universidade Federal da Bahia (UFBA) |
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UFBA |
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