Thyroid dysfunction in hepatitis C individuals treated with interferon-alpha and ribavirin: a review

Detalhes bibliográficos
Autor(a) principal: Andrade, Luis Jesuino de Oliveira
Data de Publicação: 2008
Outros Autores: Atta, Ajax Mercês, D'Almeida Junior, Argemiro, Paraná, Raymundo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/6700
Resumo: p.144-148
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spelling Andrade, Luis Jesuino de OliveiraAtta, Ajax MercêsD'Almeida Junior, ArgemiroParaná, RaymundoAndrade, Luis Jesuino de OliveiraAtta, Ajax MercêsD'Almeida Junior, ArgemiroParaná, Raymundo2012-09-06T12:08:55Z2012-09-06T12:08:55Z2008-041413-8670http://www.repositorio.ufba.br/ri/handle/ri/6700v. 12, n. 2p.144-148Hepatitis C (HCV) is now the main cause of chronic hepatic disease, cirrhosis and hepatocellular carcinoma. Several extrahepatic diseases have been associated with chronic HCV infection, and in most cases appear to be directly related to the viral infection. Thyroid disorders are common in patients with chronic HCV. Some patients with chronic hepatitis C experience thyroid problems, and thyroid dysfunction may also be a side effect of interferon-based treatment. The principal risk factor for developing thyroid disease in the course of antiviral therapy is the previous positivity for anti-thyroid antibodies (anti-thyroid peroxidase) especially in older women. Screening for autoantibodies and serum thyroid-stimulating hormone is recommended before, during and after interferon-alpha treatment, and patients should be informed of the risk of thyroid dysfunction. This review includes a summary of thyroid disease associated with chronic HCV infection, interferon-alpha and ribavirin for treatment of HCV and potential to induce thyroid dysfunction.Submitted by Texeira Ana (atanateixeira@gmail.com) on 2012-09-06T12:08:55Z No. of bitstreams: 1 Andrade, Luis Jesuíno de Oliveira.pdf: 44983 bytes, checksum: c43b7169f6fe1bfb6ce0503ac3e24070 (MD5)Made available in DSpace on 2012-09-06T12:08:55Z (GMT). No. of bitstreams: 1 Andrade, Luis Jesuíno de Oliveira.pdf: 44983 bytes, checksum: c43b7169f6fe1bfb6ce0503ac3e24070 (MD5) Previous issue date: 2008-04SalvadorThe Brazilian Journal of Infectious Diseases and Contexto Publishinghttp://dx.doi.org/10.1590/S1413-86702008000200009reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAHepatitis CInterferon-alphaRibavirinThyroid dysfunctionThyroiditisThyroid dysfunction in hepatitis C individuals treated with interferon-alpha and ribavirin: a reviewBrazilian Journal of Infectious Diseasesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleenginfo:eu-repo/semantics/openAccessORIGINALAndrade, Luis Jesuíno de Oliveira.pdfAndrade, Luis Jesuíno de Oliveira.pdfapplication/pdf44983https://repositorio.ufba.br/bitstream/ri/6700/1/Andrade%2c%20Luis%20Jesu%c3%adno%20de%20Oliveira.pdfc43b7169f6fe1bfb6ce0503ac3e24070MD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/6700/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXTAndrade, Luis Jesuíno de Oliveira.pdf.txtAndrade, Luis Jesuíno de Oliveira.pdf.txtExtracted texttext/plain28817https://repositorio.ufba.br/bitstream/ri/6700/3/Andrade%2c%20Luis%20Jesu%c3%adno%20de%20Oliveira.pdf.txt3f341d49275a6a67896760bb4a0c983bMD53ri/67002022-07-05 14:03:11.832oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:11Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Thyroid dysfunction in hepatitis C individuals treated with interferon-alpha and ribavirin: a review
dc.title.alternative.pt_BR.fl_str_mv Brazilian Journal of Infectious Diseases
title Thyroid dysfunction in hepatitis C individuals treated with interferon-alpha and ribavirin: a review
spellingShingle Thyroid dysfunction in hepatitis C individuals treated with interferon-alpha and ribavirin: a review
Andrade, Luis Jesuino de Oliveira
Hepatitis C
Interferon-alpha
Ribavirin
Thyroid dysfunction
Thyroiditis
title_short Thyroid dysfunction in hepatitis C individuals treated with interferon-alpha and ribavirin: a review
title_full Thyroid dysfunction in hepatitis C individuals treated with interferon-alpha and ribavirin: a review
title_fullStr Thyroid dysfunction in hepatitis C individuals treated with interferon-alpha and ribavirin: a review
title_full_unstemmed Thyroid dysfunction in hepatitis C individuals treated with interferon-alpha and ribavirin: a review
title_sort Thyroid dysfunction in hepatitis C individuals treated with interferon-alpha and ribavirin: a review
author Andrade, Luis Jesuino de Oliveira
author_facet Andrade, Luis Jesuino de Oliveira
Atta, Ajax Mercês
D'Almeida Junior, Argemiro
Paraná, Raymundo
author_role author
author2 Atta, Ajax Mercês
D'Almeida Junior, Argemiro
Paraná, Raymundo
author2_role author
author
author
dc.contributor.author.fl_str_mv Andrade, Luis Jesuino de Oliveira
Atta, Ajax Mercês
D'Almeida Junior, Argemiro
Paraná, Raymundo
Andrade, Luis Jesuino de Oliveira
Atta, Ajax Mercês
D'Almeida Junior, Argemiro
Paraná, Raymundo
dc.subject.por.fl_str_mv Hepatitis C
Interferon-alpha
Ribavirin
Thyroid dysfunction
Thyroiditis
topic Hepatitis C
Interferon-alpha
Ribavirin
Thyroid dysfunction
Thyroiditis
description p.144-148
publishDate 2008
dc.date.issued.fl_str_mv 2008-04
dc.date.accessioned.fl_str_mv 2012-09-06T12:08:55Z
dc.date.available.fl_str_mv 2012-09-06T12:08:55Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/6700
dc.identifier.issn.none.fl_str_mv 1413-8670
dc.identifier.number.pt_BR.fl_str_mv v. 12, n. 2
identifier_str_mv 1413-8670
v. 12, n. 2
url http://www.repositorio.ufba.br/ri/handle/ri/6700
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv The Brazilian Journal of Infectious Diseases and Contexto Publishing
publisher.none.fl_str_mv The Brazilian Journal of Infectious Diseases and Contexto Publishing
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1590/S1413-86702008000200009
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
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reponame_str Repositório Institucional da UFBA
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