Immunohistochemical assessment of CD1a-positive Langerhans cells and their relationship with E-cadherin in minor salivary gland tumors
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://repositorio.ufba.br/ri/handle/ri/16589 |
Resumo: | Texto completo: acesso restrito. p. 47–53 |
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Dultra, Fátima Karoline Araújo AlvesBarros, Adna ConceiçãoSchaer-Barbosa, HelenemarieFigueiredo, Andréia LealGurgel, Clarissa Araújo SilvaRamos, Eduardo Antônio GonçalvesCarvalho, Ana Maria da SilvaSantos, Jean Nunes dosDultra, Fátima Karoline Araújo AlvesBarros, Adna ConceiçãoSchaer-Barbosa, HelenemarieFigueiredo, Andréia LealGurgel, Clarissa Araújo SilvaRamos, Eduardo Antônio GonçalvesCarvalho, Ana Maria da SilvaSantos, Jean Nunes dos2014-11-12T15:22:47Z20120904-2512http://repositorio.ufba.br/ri/handle/ri/16589v. 41, n. 1Texto completo: acesso restrito. p. 47–53Objective: The aim of this study was to investigate the presence of CD1a-positive Langerhans cells and their relationship with E-cadherin in minor salivary gland tumors. Methods: Twenty-seven minor salivary gland tumors were investigated using immunohistochemistry for CD1a and E-cadherin. Results: A significant difference regarding the mean density of CD1a-positive Langerhans cells was observed between pleomorphic adenomas and malignant tumors studied (P = 0.001). No CD1a-positive cells were detected in most cases (n = 5) of cystic adenoid carcinomas. CD1a-positive cells were detected in one mucoepidermoid carcinoma case, and six low-grade polymorphous adenocarcinomas cases. Comparison of the mean density of CD1a-positive cells between the three malignant tumors showed no significant difference (P = 0.127). No significant difference was observed in the presence of E-cadherin between tumors (P = 0.73), but it was detected in 24 cases. Conclusions: The lack of CD1a-positive in malignant salivary gland tumors facilitates the neoplastic development and suggests that these cells might be useful as auxiliary diagnostic and prognostic tool in minor salivary gland tumors. Furthermore, it is suggested that E-cadherin mediates cell adhesion in these tumors although we did not demonstrate significance.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-11-03T14:24:40Z No. of bitstreams: 1 Fátima Karoline Araújo Alves Dultra.pdf: 590104 bytes, checksum: 281a3aad702a5aa63f43e14a85acc0f0 (MD5)Approved for entry into archive by Delba Rosa (delba@ufba.br) on 2014-11-12T15:22:47Z (GMT) No. of bitstreams: 1 Fátima Karoline Araújo Alves Dultra.pdf: 590104 bytes, checksum: 281a3aad702a5aa63f43e14a85acc0f0 (MD5)Made available in DSpace on 2014-11-12T15:22:47Z (GMT). No. of bitstreams: 1 Fátima Karoline Araújo Alves Dultra.pdf: 590104 bytes, checksum: 281a3aad702a5aa63f43e14a85acc0f0 (MD5) Previous issue date: 2012http://dx.doi.org/10.1111/j.1600-0714.2011.01052.xreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBACell adhesionDendritic cellImmunohistochemistrySalivary gland tumorsImmunohistochemical assessment of CD1a-positive Langerhans cells and their relationship with E-cadherin in minor salivary gland tumorsJournal of Oral Pathology and Medicineinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALFátima Karoline Araújo Alves Dultra.pdfFátima Karoline Araújo Alves Dultra.pdfapplication/pdf590104https://repositorio.ufba.br/bitstream/ri/16589/1/F%c3%a1tima%20Karoline%20Ara%c3%bajo%20Alves%20Dultra.pdf281a3aad702a5aa63f43e14a85acc0f0MD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/16589/2/license.txt0d4b811ef71182510d2015daa7c8a900MD52TEXTFátima Karoline Araújo Alves Dultra.pdf.txtFátima Karoline Araújo Alves Dultra.pdf.txtExtracted texttext/plain36870https://repositorio.ufba.br/bitstream/ri/16589/3/F%c3%a1tima%20Karoline%20Ara%c3%bajo%20Alves%20Dultra.pdf.txt53be5bdc269f1ea79a31c3b35d4152a8MD53ri/165892022-07-05 14:03:11.106oai:repositorio.ufba.br:ri/16589VGVybW8gZGUgTGljZW4/YSwgbj9vIGV4Y2x1c2l2bywgcGFyYSBvIGRlcD9zaXRvIG5vIFJlcG9zaXQ/cmlvIEluc3RpdHVjaW9uYWwgZGEgVUZCQS4KCiBQZWxvIHByb2Nlc3NvIGRlIHN1Ym1pc3M/byBkZSBkb2N1bWVudG9zLCBvIGF1dG9yIG91IHNldSByZXByZXNlbnRhbnRlIGxlZ2FsLCBhbyBhY2VpdGFyIAplc3NlIHRlcm1vIGRlIGxpY2VuP2EsIGNvbmNlZGUgYW8gUmVwb3NpdD9yaW8gSW5zdGl0dWNpb25hbCBkYSBVbml2ZXJzaWRhZGUgRmVkZXJhbCBkYSBCYWhpYSAKbyBkaXJlaXRvIGRlIG1hbnRlciB1bWEgYz9waWEgZW0gc2V1IHJlcG9zaXQ/cmlvIGNvbSBhIGZpbmFsaWRhZGUsIHByaW1laXJhLCBkZSBwcmVzZXJ2YT8/by4gCkVzc2VzIHRlcm1vcywgbj9vIGV4Y2x1c2l2b3MsIG1hbnQ/bSBvcyBkaXJlaXRvcyBkZSBhdXRvci9jb3B5cmlnaHQsIG1hcyBlbnRlbmRlIG8gZG9jdW1lbnRvIApjb21vIHBhcnRlIGRvIGFjZXJ2byBpbnRlbGVjdHVhbCBkZXNzYSBVbml2ZXJzaWRhZGUuCgogUGFyYSBvcyBkb2N1bWVudG9zIHB1YmxpY2Fkb3MgY29tIHJlcGFzc2UgZGUgZGlyZWl0b3MgZGUgZGlzdHJpYnVpPz9vLCBlc3NlIHRlcm1vIGRlIGxpY2VuP2EgCmVudGVuZGUgcXVlOgoKIE1hbnRlbmRvIG9zIGRpcmVpdG9zIGF1dG9yYWlzLCByZXBhc3NhZG9zIGEgdGVyY2Vpcm9zLCBlbSBjYXNvIGRlIHB1YmxpY2E/P2VzLCBvIHJlcG9zaXQ/cmlvCnBvZGUgcmVzdHJpbmdpciBvIGFjZXNzbyBhbyB0ZXh0byBpbnRlZ3JhbCwgbWFzIGxpYmVyYSBhcyBpbmZvcm1hPz9lcyBzb2JyZSBvIGRvY3VtZW50bwooTWV0YWRhZG9zIGVzY3JpdGl2b3MpLgoKIERlc3RhIGZvcm1hLCBhdGVuZGVuZG8gYW9zIGFuc2Vpb3MgZGVzc2EgdW5pdmVyc2lkYWRlIGVtIG1hbnRlciBzdWEgcHJvZHU/P28gY2llbnQ/ZmljYSBjb20gCmFzIHJlc3RyaT8/ZXMgaW1wb3N0YXMgcGVsb3MgZWRpdG9yZXMgZGUgcGVyaT9kaWNvcy4KCiBQYXJhIGFzIHB1YmxpY2E/P2VzIHNlbSBpbmljaWF0aXZhcyBxdWUgc2VndWVtIGEgcG9sP3RpY2EgZGUgQWNlc3NvIEFiZXJ0bywgb3MgZGVwP3NpdG9zIApjb21wdWxzP3Jpb3MgbmVzc2UgcmVwb3NpdD9yaW8gbWFudD9tIG9zIGRpcmVpdG9zIGF1dG9yYWlzLCBtYXMgbWFudD9tIGFjZXNzbyBpcnJlc3RyaXRvIAphbyBtZXRhZGFkb3MgZSB0ZXh0byBjb21wbGV0by4gQXNzaW0sIGEgYWNlaXRhPz9vIGRlc3NlIHRlcm1vIG4/byBuZWNlc3NpdGEgZGUgY29uc2VudGltZW50bwogcG9yIHBhcnRlIGRlIGF1dG9yZXMvZGV0ZW50b3JlcyBkb3MgZGlyZWl0b3MsIHBvciBlc3RhcmVtIGVtIGluaWNpYXRpdmFzIGRlIGFjZXNzbyBhYmVydG8uCg==Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:11Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
dc.title.pt_BR.fl_str_mv |
Immunohistochemical assessment of CD1a-positive Langerhans cells and their relationship with E-cadherin in minor salivary gland tumors |
dc.title.alternative.pt_BR.fl_str_mv |
Journal of Oral Pathology and Medicine |
title |
Immunohistochemical assessment of CD1a-positive Langerhans cells and their relationship with E-cadherin in minor salivary gland tumors |
spellingShingle |
Immunohistochemical assessment of CD1a-positive Langerhans cells and their relationship with E-cadherin in minor salivary gland tumors Dultra, Fátima Karoline Araújo Alves Cell adhesion Dendritic cell Immunohistochemistry Salivary gland tumors |
title_short |
Immunohistochemical assessment of CD1a-positive Langerhans cells and their relationship with E-cadherin in minor salivary gland tumors |
title_full |
Immunohistochemical assessment of CD1a-positive Langerhans cells and their relationship with E-cadherin in minor salivary gland tumors |
title_fullStr |
Immunohistochemical assessment of CD1a-positive Langerhans cells and their relationship with E-cadherin in minor salivary gland tumors |
title_full_unstemmed |
Immunohistochemical assessment of CD1a-positive Langerhans cells and their relationship with E-cadherin in minor salivary gland tumors |
title_sort |
Immunohistochemical assessment of CD1a-positive Langerhans cells and their relationship with E-cadherin in minor salivary gland tumors |
author |
Dultra, Fátima Karoline Araújo Alves |
author_facet |
Dultra, Fátima Karoline Araújo Alves Barros, Adna Conceição Schaer-Barbosa, Helenemarie Figueiredo, Andréia Leal Gurgel, Clarissa Araújo Silva Ramos, Eduardo Antônio Gonçalves Carvalho, Ana Maria da Silva Santos, Jean Nunes dos |
author_role |
author |
author2 |
Barros, Adna Conceição Schaer-Barbosa, Helenemarie Figueiredo, Andréia Leal Gurgel, Clarissa Araújo Silva Ramos, Eduardo Antônio Gonçalves Carvalho, Ana Maria da Silva Santos, Jean Nunes dos |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Dultra, Fátima Karoline Araújo Alves Barros, Adna Conceição Schaer-Barbosa, Helenemarie Figueiredo, Andréia Leal Gurgel, Clarissa Araújo Silva Ramos, Eduardo Antônio Gonçalves Carvalho, Ana Maria da Silva Santos, Jean Nunes dos Dultra, Fátima Karoline Araújo Alves Barros, Adna Conceição Schaer-Barbosa, Helenemarie Figueiredo, Andréia Leal Gurgel, Clarissa Araújo Silva Ramos, Eduardo Antônio Gonçalves Carvalho, Ana Maria da Silva Santos, Jean Nunes dos |
dc.subject.por.fl_str_mv |
Cell adhesion Dendritic cell Immunohistochemistry Salivary gland tumors |
topic |
Cell adhesion Dendritic cell Immunohistochemistry Salivary gland tumors |
description |
Texto completo: acesso restrito. p. 47–53 |
publishDate |
2012 |
dc.date.issued.fl_str_mv |
2012 |
dc.date.accessioned.fl_str_mv |
2014-11-12T15:22:47Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://repositorio.ufba.br/ri/handle/ri/16589 |
dc.identifier.issn.none.fl_str_mv |
0904-2512 |
dc.identifier.number.pt_BR.fl_str_mv |
v. 41, n. 1 |
identifier_str_mv |
0904-2512 v. 41, n. 1 |
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http://repositorio.ufba.br/ri/handle/ri/16589 |
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eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
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