Identification of novel recombinants of hepatitis B virus genotypes F and G in human immunodeficiency virus-positive patients from Argentina and Brazil
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://repositorio.ufba.br/ri/handle/ri/17666 |
Resumo: | Texto completo: acesso restrito. p.150-158 |
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Araujo, Natália Motta deAraujo, Oscar Rafael CarmoSilva, Edinete Melo daVillella-Nogueira, Cristiane AlvesNabuco, Letícia CancellaParaná, RaymundoBessone, FernandoGomes, Selma de AndradeTrepo, ChristianKay, Alan CampbellAraujo, Natália Motta deAraujo, Oscar Rafael CarmoSilva, Edinete Melo daVillella-Nogueira, Cristiane AlvesNabuco, Letícia CancellaParaná, RaymundoBessone, FernandoGomes, Selma de AndradeTrepo, ChristianKay, Alan Campbell2015-05-11T15:42:35Z20130022-1317http://repositorio.ufba.br/ri/handle/ri/17666v. 94, n. 1Texto completo: acesso restrito. p.150-158Hepatitis B virus (HBV) genotype G (HBV/G) infection is almost always detected along with a co-infecting HBV strain that can supply HBeAg, typically HBV/A2. In this study we describe, in two human immunodeficiency virus (HIV)-positive patients from Argentina and Brazil, the first report of HBV/G infection in Argentina and co-circulation of HBV/G, HBV/F and G/F recombinants in the American continent. HBV isolates carrying the 36 bp insertion of HBV/G were the most prevalent in both patients, with >99 % of colonies hybridizing to a probe specific for this insertion. Phylogenetic analyses of full-length genomes and precore/core fragments revealed that F4 and F1b were the co-infecting subgenotypes in the Brazilian and Argentinian patients, respectively. Bootscanning analysis provided evidence of recombination in several clones from both patients, with recombination breakpoints located mainly at the precore/core region. These data should encourage further investigations on the clinical implications of HBV/G recombinants in HBV/HIV co-infected patients.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2015-03-10T13:50:44Z No. of bitstreams: 1 Natalia M. Araujo.pdf: 896646 bytes, checksum: 7eba9de9cc6e8fa9509d948206b46a76 (MD5)Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2015-05-11T15:42:35Z (GMT) No. of bitstreams: 1 Natalia M. Araujo.pdf: 896646 bytes, checksum: 7eba9de9cc6e8fa9509d948206b46a76 (MD5)Made available in DSpace on 2015-05-11T15:42:35Z (GMT). No. of bitstreams: 1 Natalia M. Araujo.pdf: 896646 bytes, checksum: 7eba9de9cc6e8fa9509d948206b46a76 (MD5) Previous issue date: 2013http://dx.doi.org/10.1099/vir.0.047324-0reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAHepatitis BHepatitis B virusHBeAgAIDS SerodiagnosisIdentification of novel recombinants of hepatitis B virus genotypes F and G in human immunodeficiency virus-positive patients from Argentina and BrazilJournal of General Virologyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALNatalia M. Araujo.pdfNatalia M. 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dc.title.pt_BR.fl_str_mv |
Identification of novel recombinants of hepatitis B virus genotypes F and G in human immunodeficiency virus-positive patients from Argentina and Brazil |
dc.title.alternative.pt_BR.fl_str_mv |
Journal of General Virology |
title |
Identification of novel recombinants of hepatitis B virus genotypes F and G in human immunodeficiency virus-positive patients from Argentina and Brazil |
spellingShingle |
Identification of novel recombinants of hepatitis B virus genotypes F and G in human immunodeficiency virus-positive patients from Argentina and Brazil Araujo, Natália Motta de Hepatitis B Hepatitis B virus HBeAg AIDS Serodiagnosis |
title_short |
Identification of novel recombinants of hepatitis B virus genotypes F and G in human immunodeficiency virus-positive patients from Argentina and Brazil |
title_full |
Identification of novel recombinants of hepatitis B virus genotypes F and G in human immunodeficiency virus-positive patients from Argentina and Brazil |
title_fullStr |
Identification of novel recombinants of hepatitis B virus genotypes F and G in human immunodeficiency virus-positive patients from Argentina and Brazil |
title_full_unstemmed |
Identification of novel recombinants of hepatitis B virus genotypes F and G in human immunodeficiency virus-positive patients from Argentina and Brazil |
title_sort |
Identification of novel recombinants of hepatitis B virus genotypes F and G in human immunodeficiency virus-positive patients from Argentina and Brazil |
author |
Araujo, Natália Motta de |
author_facet |
Araujo, Natália Motta de Araujo, Oscar Rafael Carmo Silva, Edinete Melo da Villella-Nogueira, Cristiane Alves Nabuco, Letícia Cancella Paraná, Raymundo Bessone, Fernando Gomes, Selma de Andrade Trepo, Christian Kay, Alan Campbell |
author_role |
author |
author2 |
Araujo, Oscar Rafael Carmo Silva, Edinete Melo da Villella-Nogueira, Cristiane Alves Nabuco, Letícia Cancella Paraná, Raymundo Bessone, Fernando Gomes, Selma de Andrade Trepo, Christian Kay, Alan Campbell |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Araujo, Natália Motta de Araujo, Oscar Rafael Carmo Silva, Edinete Melo da Villella-Nogueira, Cristiane Alves Nabuco, Letícia Cancella Paraná, Raymundo Bessone, Fernando Gomes, Selma de Andrade Trepo, Christian Kay, Alan Campbell Araujo, Natália Motta de Araujo, Oscar Rafael Carmo Silva, Edinete Melo da Villella-Nogueira, Cristiane Alves Nabuco, Letícia Cancella Paraná, Raymundo Bessone, Fernando Gomes, Selma de Andrade Trepo, Christian Kay, Alan Campbell |
dc.subject.por.fl_str_mv |
Hepatitis B Hepatitis B virus HBeAg AIDS Serodiagnosis |
topic |
Hepatitis B Hepatitis B virus HBeAg AIDS Serodiagnosis |
description |
Texto completo: acesso restrito. p.150-158 |
publishDate |
2013 |
dc.date.issued.fl_str_mv |
2013 |
dc.date.accessioned.fl_str_mv |
2015-05-11T15:42:35Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
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http://repositorio.ufba.br/ri/handle/ri/17666 |
dc.identifier.issn.none.fl_str_mv |
0022-1317 |
dc.identifier.number.pt_BR.fl_str_mv |
v. 94, n. 1 |
identifier_str_mv |
0022-1317 v. 94, n. 1 |
url |
http://repositorio.ufba.br/ri/handle/ri/17666 |
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eng |
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