Screening for depression in hemodialysis patients: Associations with diagnosis, treatment, and outcomes in the DOPPS

Detalhes bibliográficos
Autor(a) principal: Lopes, Antonio Alberto da Silva
Data de Publicação: 2004
Outros Autores: Albert, Justin M., Young, Eric W., Satayathum, Sudtida, Pisoni, Ronald L.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/7027
Resumo: p. 2047–2053
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spelling Lopes, Antonio Alberto da SilvaAlbert, Justin M.Young, Eric W.Satayathum, SudtidaPisoni, Ronald L.Lopes, Antonio Alberto da SilvaAlbert, Justin M.Young, Eric W.Satayathum, SudtidaPisoni, Ronald L.2012-10-23T13:26:48Z20040085-2538http://www.repositorio.ufba.br/ri/handle/ri/7027v. 66p. 2047–2053Screening for depression in hemodialysis patients: Associations with diagnosis, treatment, and outcomes in the DOPPS. Background Depressive symptoms and depression are the most frequent psychologic problems reported by hemodialysis patients. We assessed the prevalence of depressive symptoms and physician-diagnosed depression, their variations by country, and associations with treatment by antidepressants among hemodialysis patients. We also assessed whether depressive symptoms were independently associated with mortality, hospitalization, and dialysis withdrawal. Methods The sample was represented by 9382 hemodialysis patients randomly selected from dialysis centers of 12 countries enrolled in the Dialysis Outcomes and Practice Patterns Study (DOPPS II). Depressive symptoms were assessed by the short version of the Center for Epidemiological Studies Depression Screening Index (CES-D), using greater than or equal to10 CES-D score as the cut-off value. Results Overall prevalence of physician-diagnosed depression was 13.9%, and percentage of CES-D score greater than or equal to10 43.0%. While the smallest prevalence of physician-diagnosed depression was observed in Japan (2.0%) and France (10.6%), the percentage of CES-D score greater than or equal to10 in these counties was similar to the whole sample. Patients on antidepressants also varied by country, 34.9% and 17.3% among those with physician-diagnosed depression and CES-D scores greater than or equal to10, respectively. In Cox models adjusted for several comorbidities, CES-D scores greater than or equal to10 were associated with significantly higher relative risks (RR) of death (RR = 1.42; 95% CI = 1.29 to 1.57), hospitalization (RR = 1.12; 95% CI = 1.03 to 1.22), and dialysis withdrawal (RR = 1.55; 95% CI = 1.29 to 1.85). Conclusion The data suggest that depression is underdiagnosed and undertreated among hemodialysis patients. CES-D can help identify hemodialysis patients who are at higher risk of death and hospitalization. Interventions should target these patients with the goal to improve survival and reduce hospitalizations.Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2012-10-23T13:26:48Z No. of bitstreams: 1 C__Documents and Settings_rep...t.default_Cache_6_E0ÍE6d01.pdf: 96848 bytes, checksum: 4feee87bdee62aa1b80cf862b04d6360 (MD5)Made available in DSpace on 2012-10-23T13:26:48Z (GMT). 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dc.title.pt_BR.fl_str_mv Screening for depression in hemodialysis patients: Associations with diagnosis, treatment, and outcomes in the DOPPS
dc.title.alternative.pt_BR.fl_str_mv Kidney International
title Screening for depression in hemodialysis patients: Associations with diagnosis, treatment, and outcomes in the DOPPS
spellingShingle Screening for depression in hemodialysis patients: Associations with diagnosis, treatment, and outcomes in the DOPPS
Lopes, Antonio Alberto da Silva
depression
dialysis
end-stage renal disease
hospitalization
mortality
title_short Screening for depression in hemodialysis patients: Associations with diagnosis, treatment, and outcomes in the DOPPS
title_full Screening for depression in hemodialysis patients: Associations with diagnosis, treatment, and outcomes in the DOPPS
title_fullStr Screening for depression in hemodialysis patients: Associations with diagnosis, treatment, and outcomes in the DOPPS
title_full_unstemmed Screening for depression in hemodialysis patients: Associations with diagnosis, treatment, and outcomes in the DOPPS
title_sort Screening for depression in hemodialysis patients: Associations with diagnosis, treatment, and outcomes in the DOPPS
author Lopes, Antonio Alberto da Silva
author_facet Lopes, Antonio Alberto da Silva
Albert, Justin M.
Young, Eric W.
Satayathum, Sudtida
Pisoni, Ronald L.
author_role author
author2 Albert, Justin M.
Young, Eric W.
Satayathum, Sudtida
Pisoni, Ronald L.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Lopes, Antonio Alberto da Silva
Albert, Justin M.
Young, Eric W.
Satayathum, Sudtida
Pisoni, Ronald L.
Lopes, Antonio Alberto da Silva
Albert, Justin M.
Young, Eric W.
Satayathum, Sudtida
Pisoni, Ronald L.
dc.subject.por.fl_str_mv depression
dialysis
end-stage renal disease
hospitalization
mortality
topic depression
dialysis
end-stage renal disease
hospitalization
mortality
description p. 2047–2053
publishDate 2004
dc.date.issued.fl_str_mv 2004
dc.date.accessioned.fl_str_mv 2012-10-23T13:26:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/7027
dc.identifier.issn.none.fl_str_mv 0085-2538
dc.identifier.number.pt_BR.fl_str_mv v. 66
identifier_str_mv 0085-2538
v. 66
url http://www.repositorio.ufba.br/ri/handle/ri/7027
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv doi:10.1111/j.1523-1755.2004.00977.x
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
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institution UFBA
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