Is there an association between suicide attempt and delay of initiation of mood stabilizers in bipolar I disorder?

Detalhes bibliográficos
Autor(a) principal: Fernandes, Fabiana Nery
Data de Publicação: 2012
Outros Autores: Quarantini, Lucas de Castro, Guimarães, José L., Oliveira, Irismar R. de, Koenen, Karestan C., Kapczinski, Flavio, Scippa, Ângela Marisa de Aquino Miranda
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/16190
Resumo: Texto completo: acesso restrito. p. 1082–1087
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spelling Fernandes, Fabiana NeryQuarantini, Lucas de CastroGuimarães, José L.Oliveira, Irismar R. deKoenen, Karestan C.Kapczinski, FlavioScippa, Ângela Marisa de Aquino MirandaFernandes, Fabiana NeryQuarantini, Lucas de CastroGuimarães, José L.Oliveira, Irismar R. deKoenen, Karestan C.Kapczinski, FlavioScippa, Ângela Marisa de Aquino Miranda2014-09-29T15:20:43Z20120165-0327http://repositorio.ufba.br/ri/handle/ri/16190v. 136, n. 3Texto completo: acesso restrito. p. 1082–1087Background Little is known about the extent to which delay of initiation of mood-stabilizing treatment may influence outcomes in bipolar patients (BP). In this study, our aim was to investigate the association between delay of mood stabilizer treatment in bipolar patients and lifetime history of suicide attempts. Method A consecutive sample of 268 bipolar I outpatients from two teaching hospitals in Brazil was recruited. The assessment included a socio-demographic history form, a clinical interview regarding clinical variables and the Structured Clinical Interview for DSM-IV. Participants were divided into three groups: BP that initiated the first mood stabilizer in the same year of the first episode of the disease (FMS ≤ 1), between 1 and 5 years after the first episode of the disease (1 < FMS ≤ 5), and after 5 years after the first episode of BD (FMS > 5). Results The mean time from the first episode until the first mood stabilizer medication was 8.6 years (SD 9.8 years). The FMS > 5 group, showed a higher lifetime prevalence of suicide attempts than the other two groups (PR = 1.75, 95% CI: 1.24–2.47), p = 0.001. These results remained significant after adjusting for potential confounders, (PR = 1.82, 95% CI: 1.29–2.60), p = 0.001. Limitations This study evaluated patients retrospectively and does not permit a cause-effect relationship. Conclusion The present study supports the importance of early diagnosis and early intervention for BP in order to limit the potentially lethal impact of the diseaseSubmitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-08-25T15:00:30Z No. of bitstreams: 1 Fabiana Nery Fernandes.pdf: 179786 bytes, checksum: 3cceada9edaecb30fb9e6e8b88e568f1 (MD5)Approved for entry into archive by Delba Rosa (delba@ufba.br) on 2014-09-29T15:20:43Z (GMT) No. of bitstreams: 1 Fabiana Nery Fernandes.pdf: 179786 bytes, checksum: 3cceada9edaecb30fb9e6e8b88e568f1 (MD5)Made available in DSpace on 2014-09-29T15:20:43Z (GMT). No. of bitstreams: 1 Fabiana Nery Fernandes.pdf: 179786 bytes, checksum: 3cceada9edaecb30fb9e6e8b88e568f1 (MD5) Previous issue date: 2012http://dx.doi.org/ 10.1016/j.jad.2011.10.046reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBABipolar disorderTreatmentMood stabilizerSuicide attemptSuicidal behaviorIs there an association between suicide attempt and delay of initiation of mood stabilizers in bipolar I disorder?Journal of Affective Disordersinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALFabiana Nery Fernandes.pdfFabiana Nery Fernandes.pdfapplication/pdf179786https://repositorio.ufba.br/bitstream/ri/16190/1/Fabiana%20Nery%20Fernandes.pdf3cceada9edaecb30fb9e6e8b88e568f1MD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/16190/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXTFabiana Nery Fernandes.pdf.txtFabiana Nery Fernandes.pdf.txtExtracted texttext/plain36822https://repositorio.ufba.br/bitstream/ri/16190/3/Fabiana%20Nery%20Fernandes.pdf.txt86beb3444328cecba09086a8ddee4f6aMD53ri/161902022-07-05 14:03:31.251oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:31Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Is there an association between suicide attempt and delay of initiation of mood stabilizers in bipolar I disorder?
dc.title.alternative.pt_BR.fl_str_mv Journal of Affective Disorders
title Is there an association between suicide attempt and delay of initiation of mood stabilizers in bipolar I disorder?
spellingShingle Is there an association between suicide attempt and delay of initiation of mood stabilizers in bipolar I disorder?
Fernandes, Fabiana Nery
Bipolar disorder
Treatment
Mood stabilizer
Suicide attempt
Suicidal behavior
title_short Is there an association between suicide attempt and delay of initiation of mood stabilizers in bipolar I disorder?
title_full Is there an association between suicide attempt and delay of initiation of mood stabilizers in bipolar I disorder?
title_fullStr Is there an association between suicide attempt and delay of initiation of mood stabilizers in bipolar I disorder?
title_full_unstemmed Is there an association between suicide attempt and delay of initiation of mood stabilizers in bipolar I disorder?
title_sort Is there an association between suicide attempt and delay of initiation of mood stabilizers in bipolar I disorder?
author Fernandes, Fabiana Nery
author_facet Fernandes, Fabiana Nery
Quarantini, Lucas de Castro
Guimarães, José L.
Oliveira, Irismar R. de
Koenen, Karestan C.
Kapczinski, Flavio
Scippa, Ângela Marisa de Aquino Miranda
author_role author
author2 Quarantini, Lucas de Castro
Guimarães, José L.
Oliveira, Irismar R. de
Koenen, Karestan C.
Kapczinski, Flavio
Scippa, Ângela Marisa de Aquino Miranda
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Fernandes, Fabiana Nery
Quarantini, Lucas de Castro
Guimarães, José L.
Oliveira, Irismar R. de
Koenen, Karestan C.
Kapczinski, Flavio
Scippa, Ângela Marisa de Aquino Miranda
Fernandes, Fabiana Nery
Quarantini, Lucas de Castro
Guimarães, José L.
Oliveira, Irismar R. de
Koenen, Karestan C.
Kapczinski, Flavio
Scippa, Ângela Marisa de Aquino Miranda
dc.subject.por.fl_str_mv Bipolar disorder
Treatment
Mood stabilizer
Suicide attempt
Suicidal behavior
topic Bipolar disorder
Treatment
Mood stabilizer
Suicide attempt
Suicidal behavior
description Texto completo: acesso restrito. p. 1082–1087
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2014-09-29T15:20:43Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/16190
dc.identifier.issn.none.fl_str_mv 0165-0327
dc.identifier.number.pt_BR.fl_str_mv v. 136, n. 3
identifier_str_mv 0165-0327
v. 136, n. 3
url http://repositorio.ufba.br/ri/handle/ri/16190
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/ 10.1016/j.jad.2011.10.046
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instname:Universidade Federal da Bahia (UFBA)
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