Chronic myeloid leukaemia in two multiple sclerosis patients on interferon beta-1a
Autor(a) principal: | |
---|---|
Data de Publicação: | 2009 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/5853 |
Resumo: | Acesso restrito: Texto completo. p. 125-127 |
id |
UFBA-2_26562e533d4d5997afbea4d92ec21083 |
---|---|
oai_identifier_str |
oai:repositorio.ufba.br:ri/5853 |
network_acronym_str |
UFBA-2 |
network_name_str |
Repositório Institucional da UFBA |
repository_id_str |
1932 |
spelling |
Almeida, L.Neves, MarciaCardoso, EduardoMelo, Ailton de SouzaAlmeida, L.Neves, MarciaCardoso, EduardoMelo, Ailton de Souza2012-05-14T18:52:13Z20090269-4727http://www.repositorio.ufba.br/ri/handle/ri/5853v. 34, n. 1Acesso restrito: Texto completo. p. 125-127Haematological problems are commonly associated with use of beta-interferon in multiple sclerosis (MS) patients. However these problems are usually benign and are reversible when the drug is stopped. We describe two patients, with the diagnosis of MS, who developed leucocytosis. Cytogenetic studies showed the presence of the Philadelphia chromosome in all the cells analysed, confirming the diagnosis of chronic myeloid leukaemia (CML). The first patient currently on imatimib mesylate and interferon beta-1a is asymptomatic. For the second patient, interferon beta-1a was withdrawn after suspicion of CML.Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2012-05-14T18:52:13Z No. of bitstreams: 1 __onlinelibrary.wiley.co...575a71e9004b3beb722a17716e4f7.pdf: 60571 bytes, checksum: 10d0ba44ff63680dbc49c3f86bd24e88 (MD5)Made available in DSpace on 2012-05-14T18:52:13Z (GMT). No. of bitstreams: 1 __onlinelibrary.wiley.co...575a71e9004b3beb722a17716e4f7.pdf: 60571 bytes, checksum: 10d0ba44ff63680dbc49c3f86bd24e88 (MD5) Previous issue date: 2009http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2710.2008.00983.x/abstract;jsessionid=0E3D7D8A0183E8583468FA035108053C.d01t02reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAChronic myeloid leukaemiaEncephalitisInterferonLeucocytosisMultiple sclerosisPhiladelphia chromosomeSide effectsChronic myeloid leukaemia in two multiple sclerosis patients on interferon beta-1aJournal of Clinical Pharmacy and Therapeuticsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01enginfo:eu-repo/semantics/openAccessORIGINAL__onlinelibrary.wiley.co...575a71e9004b3beb722a17716e4f7.pdf__onlinelibrary.wiley.co...575a71e9004b3beb722a17716e4f7.pdfapplication/pdf60571https://repositorio.ufba.br/bitstream/ri/5853/1/__onlinelibrary.wiley.co...575a71e9004b3beb722a17716e4f7.pdf10d0ba44ff63680dbc49c3f86bd24e88MD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/5853/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXT__onlinelibrary.wiley.co...575a71e9004b3beb722a17716e4f7.pdf.txt__onlinelibrary.wiley.co...575a71e9004b3beb722a17716e4f7.pdf.txtExtracted texttext/plain8900https://repositorio.ufba.br/bitstream/ri/5853/3/__onlinelibrary.wiley.co...575a71e9004b3beb722a17716e4f7.pdf.txte7d752e5fab3def3fc7c391e51f29ab1MD53ri/58532022-08-26 11:02:28.56oai:repositorio.ufba.br:ri/5853VGVybW8gZGUgTGljZW7vv71hLCBu77+9byBleGNsdXNpdm8sIHBhcmEgbyBkZXDvv71zaXRvIG5vIHJlcG9zaXTvv71yaW8gSW5zdGl0dWNpb25hbCBkYSBVRkJBCgogICAgUGVsbyBwcm9jZXNzbyBkZSBzdWJtaXNz77+9byBkZSBkb2N1bWVudG9zLCBvIGF1dG9yIG91IHNldQpyZXByZXNlbnRhbnRlIGxlZ2FsLCBhbyBhY2VpdGFyIGVzc2UgdGVybW8gZGUgbGljZW7vv71hLCBjb25jZWRlIGFvClJlcG9zaXTvv71yaW8gSW5zdGl0dWNpb25hbCBkYSBVbml2ZXJzaWRhZGUgRmVkZXJhbCBkYSBCYWhpYSBvIGRpcmVpdG8KZGUgbWFudGVyIHVtYSBj77+9cGlhIGVtIHNldSByZXBvc2l077+9cmlvIGNvbSBhIGZpbmFsaWRhZGUsIHByaW1laXJhLCAKZGUgcHJlc2VydmHvv73vv71vLiBFc3NlcyB0ZXJtb3MsIG7vv71vIGV4Y2x1c2l2b3MsIG1hbnTvv71tIG9zIGRpcmVpdG9zIGRlIAphdXRvci9jb3B5cmlnaHQsIG1hcyBlbnRlbmRlIG8gZG9jdW1lbnRvIGNvbW8gcGFydGUgZG8gYWNlcnZvIGludGVsZWN0dWFsIGRlc3NhIFVuaXZlcnNpZGFkZS4gCgogICAgUGFyYSBvcyBkb2N1bWVudG9zIHB1YmxpY2Fkb3MgY29tIHJlcGFzc2UgZGUgZGlyZWl0b3MgZGUgZGlzdHJpYnVp77+977+9bywgZXNzZSB0ZXJtbyBkZSBsaWNlbu+/vWEgZW50ZW5kZSBxdWU6IAoKICAgIE1hbnRlbmRvIG9zICBkaXJlaXRvcyBhdXRvcmFpcywgcmVwYXNzYWRvcyBhIHRlcmNlaXJvcywgZW0gY2FzbyAKZGUgcHVibGljYe+/ve+/vWVzLCBvIHJlcG9zaXTvv71yaW8gcG9kZSByZXN0cmluZ2lyIG8gYWNlc3NvIGFvIHRleHRvIAppbnRlZ3JhbCwgbWFzIGxpYmVyYSBhcyBpbmZvcm1h77+977+9ZXMgc29icmUgbyBkb2N1bWVudG8gKE1ldGFkYWRvcyBkZXNjcml0aXZvcykuCgogRGVzdGEgZm9ybWEsIGF0ZW5kZW5kbyBhb3MgYW5zZWlvcyBkZXNzYSB1bml2ZXJzaWRhZGUgCmVtIG1hbnRlciBzdWEgcHJvZHXvv73vv71vIGNpZW5077+9ZmljYSBjb20gYXMgcmVzdHJp77+977+9ZXMgaW1wb3N0YXMgcGVsb3MgCmVkaXRvcmVzIGRlIHBlcmnvv71kaWNvcy4gCgogICAgUGFyYSBhcyBwdWJsaWNh77+977+9ZXMgZW0gaW5pY2lhdGl2YXMgcXVlIHNlZ3VlbSBhIHBvbO+/vXRpY2EgZGUgCkFjZXNzbyBBYmVydG8sIG9zIGRlcO+/vXNpdG9zIGNvbXB1bHPvv71yaW9zIG5lc3NlIHJlcG9zaXTvv71yaW8gbWFudO+/vW0gCm9zIGRpcmVpdG9zIGF1dG9yYWlzLCBtYXMgbWFudO+/vW0gbyBhY2Vzc28gaXJyZXN0cml0byBhbyBtZXRhZGFkb3MgCmUgdGV4dG8gY29tcGxldG8uIEFzc2ltLCBhIGFjZWl0Ye+/ve+/vW8gZGVzc2UgdGVybW8gbu+/vW8gbmVjZXNzaXRhIGRlIApjb25zZW50aW1lbnRvIHBvciBwYXJ0ZSBkZSBhdXRvcmVzL2RldGVudG9yZXMgZG9zIGRpcmVpdG9zLCBwb3IgCmVzdGFyZW0gZW0gaW5pY2lhdGl2YXMgZGUgYWNlc3NvIGFiZXJ0by4KCiAgICBFbSBhbWJvcyBvIGNhc28sIGVzc2UgdGVybW8gZGUgbGljZW7vv71hLCBwb2RlIHNlciBhY2VpdG8gcGVsbyAKYXV0b3IsIGRldGVudG9yZXMgZGUgZGlyZWl0b3MgZS9vdSB0ZXJjZWlyb3MgYW1wYXJhZG9zIHBlbGEgCnVuaXZlcnNpZGFkZS4gRGV2aWRvIGFvcyBkaWZlcmVudGVzIHByb2Nlc3NvcyBwZWxvIHF1YWwgYSBzdWJtaXNz77+9byAKcG9kZSBvY29ycmVyLCBvIHJlcG9zaXTvv71yaW8gcGVybWl0ZSBhIGFjZWl0Ye+/ve+/vW8gZGEgbGljZW7vv71hIHBvciAKdGVyY2Vpcm9zLCBzb21lbnRlIG5vcyBjYXNvcyBkZSBkb2N1bWVudG9zIHByb2R1emlkb3MgcG9yIGludGVncmFudGVzIApkYSBVRkJBIGUgc3VibWV0aWRvcyBwb3IgcGVzc29hcyBhbXBhcmFkYXMgcG9yIGVzdGEgaW5zdGl0dWnvv73vv71vLgo=Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-08-26T14:02:28Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
dc.title.pt_BR.fl_str_mv |
Chronic myeloid leukaemia in two multiple sclerosis patients on interferon beta-1a |
dc.title.alternative.pt_BR.fl_str_mv |
Journal of Clinical Pharmacy and Therapeutics |
title |
Chronic myeloid leukaemia in two multiple sclerosis patients on interferon beta-1a |
spellingShingle |
Chronic myeloid leukaemia in two multiple sclerosis patients on interferon beta-1a Almeida, L. Chronic myeloid leukaemia Encephalitis Interferon Leucocytosis Multiple sclerosis Philadelphia chromosome Side effects |
title_short |
Chronic myeloid leukaemia in two multiple sclerosis patients on interferon beta-1a |
title_full |
Chronic myeloid leukaemia in two multiple sclerosis patients on interferon beta-1a |
title_fullStr |
Chronic myeloid leukaemia in two multiple sclerosis patients on interferon beta-1a |
title_full_unstemmed |
Chronic myeloid leukaemia in two multiple sclerosis patients on interferon beta-1a |
title_sort |
Chronic myeloid leukaemia in two multiple sclerosis patients on interferon beta-1a |
author |
Almeida, L. |
author_facet |
Almeida, L. Neves, Marcia Cardoso, Eduardo Melo, Ailton de Souza |
author_role |
author |
author2 |
Neves, Marcia Cardoso, Eduardo Melo, Ailton de Souza |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Almeida, L. Neves, Marcia Cardoso, Eduardo Melo, Ailton de Souza Almeida, L. Neves, Marcia Cardoso, Eduardo Melo, Ailton de Souza |
dc.subject.por.fl_str_mv |
Chronic myeloid leukaemia Encephalitis Interferon Leucocytosis Multiple sclerosis Philadelphia chromosome Side effects |
topic |
Chronic myeloid leukaemia Encephalitis Interferon Leucocytosis Multiple sclerosis Philadelphia chromosome Side effects |
description |
Acesso restrito: Texto completo. p. 125-127 |
publishDate |
2009 |
dc.date.issued.fl_str_mv |
2009 |
dc.date.accessioned.fl_str_mv |
2012-05-14T18:52:13Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.repositorio.ufba.br/ri/handle/ri/5853 |
dc.identifier.issn.none.fl_str_mv |
0269-4727 |
dc.identifier.number.pt_BR.fl_str_mv |
v. 34, n. 1 |
identifier_str_mv |
0269-4727 v. 34, n. 1 |
url |
http://www.repositorio.ufba.br/ri/handle/ri/5853 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.pt_BR.fl_str_mv |
http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2710.2008.00983.x/abstract;jsessionid=0E3D7D8A0183E8583468FA035108053C.d01t02 |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFBA instname:Universidade Federal da Bahia (UFBA) instacron:UFBA |
instname_str |
Universidade Federal da Bahia (UFBA) |
instacron_str |
UFBA |
institution |
UFBA |
reponame_str |
Repositório Institucional da UFBA |
collection |
Repositório Institucional da UFBA |
bitstream.url.fl_str_mv |
https://repositorio.ufba.br/bitstream/ri/5853/1/__onlinelibrary.wiley.co...575a71e9004b3beb722a17716e4f7.pdf https://repositorio.ufba.br/bitstream/ri/5853/2/license.txt https://repositorio.ufba.br/bitstream/ri/5853/3/__onlinelibrary.wiley.co...575a71e9004b3beb722a17716e4f7.pdf.txt |
bitstream.checksum.fl_str_mv |
10d0ba44ff63680dbc49c3f86bd24e88 1b89a9a0548218172d7c829f87a0eab9 e7d752e5fab3def3fc7c391e51f29ab1 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA) |
repository.mail.fl_str_mv |
|
_version_ |
1808459398419316736 |