Determination of N,N-dimethyltryptamine in beverages consumed in religious practices by headspace solid-phase microextraction followed by gas chromatography ion trap mass spectrometry

Detalhes bibliográficos
Autor(a) principal: Gaujac, Alain
Data de Publicação: 2013
Outros Autores: Dempster, Nicola M., Navickiene, Sandro, Brandt, Simon D., Andrade, Jailson Bittencourt de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/16815
Resumo: Texto completo: acesso restrito. p. 394–398
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spelling Gaujac, AlainDempster, Nicola M.Navickiene, SandroBrandt, Simon D.Andrade, Jailson Bittencourt deGaujac, AlainDempster, Nicola M.Navickiene, SandroBrandt, Simon D.Andrade, Jailson Bittencourt de2014-12-17T12:01:48Z20130039-9140http://repositorio.ufba.br/ri/handle/ri/16815v. 106, n. 15Texto completo: acesso restrito. p. 394–398A novel analytical approach combining solid-phase microextraction (SPME)/gas chromatography ion trap mass spectrometry (GC-IT-MS) was developed for the detection and quantification N,N-dimethyltryptamine (DMT), a powerful psychoactive indole alkaloid present in a variety of South American indigenous beverages, such as ayahuasca and vinho da jurema. These particular plant products, often used within a religious context, are increasingly consumed throughout the world following an expansion of religious groups and the availability of plant material over the Internet and high street shops. The method described in the present study included the use of SPME in headspace mode combined GC-IT-MS and included the optimization of the SPME procedure using multivariate techniques. The method was performed with a polydimethylsiloxane/divinylbenzene (PDMS/DVB) fiber in headspace mode (70 min at 60 °C) which resulted in good precision (RSD<8.6%) and accuracy values (71–109%). Detection and quantification limits obtained for DMT were 0.78 and 9.5 mg L−1, respectively and good linearity (1.56–300 mg L−1, r2=0.9975) was also observed. In addition, the proposed method showed good robustness and allowed for the minimization of sample manipulation. Five jurema beverage samples were prepared in the laboratory in order to study the impact of temperature, pH and ethanol on the ability to extract DMT into solution. The developed method was then applied to the analysis of twelve real ayahuasca and vinho da jurema samples, obtained from Brazilian religious groups, which revealed DMT concentration levels between 0.10 and 1.81 g L−1.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-12-17T12:01:47Z No. of bitstreams: 1 Alain Gaujac.pdf: 598440 bytes, checksum: 7b87708466a4f2882a3df99622aa2b87 (MD5)Made available in DSpace on 2014-12-17T12:01:48Z (GMT). No. of bitstreams: 1 Alain Gaujac.pdf: 598440 bytes, checksum: 7b87708466a4f2882a3df99622aa2b87 (MD5) Previous issue date: 2013http://dx.doi.org/ 10.1016/j.talanta.2013.01.017reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBADMTVinho da juremaAyahuascaMultivariate optimizationSPME/GC–MSDetermination of N,N-dimethyltryptamine in beverages consumed in religious practices by headspace solid-phase microextraction followed by gas chromatography ion trap mass spectrometryTalantainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALAlain Gaujac.pdfAlain Gaujac.pdfapplication/pdf598440https://repositorio.ufba.br/bitstream/ri/16815/1/Alain%20Gaujac.pdf7b87708466a4f2882a3df99622aa2b87MD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/16815/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXTAlain Gaujac.pdf.txtAlain Gaujac.pdf.txtExtracted texttext/plain21415https://repositorio.ufba.br/bitstream/ri/16815/3/Alain%20Gaujac.pdf.txt3b2dfa62eb04fde1d939d63f399a2354MD53ri/168152022-08-08 13:18:06.231oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-08-08T16:18:06Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Determination of N,N-dimethyltryptamine in beverages consumed in religious practices by headspace solid-phase microextraction followed by gas chromatography ion trap mass spectrometry
dc.title.alternative.pt_BR.fl_str_mv Talanta
title Determination of N,N-dimethyltryptamine in beverages consumed in religious practices by headspace solid-phase microextraction followed by gas chromatography ion trap mass spectrometry
spellingShingle Determination of N,N-dimethyltryptamine in beverages consumed in religious practices by headspace solid-phase microextraction followed by gas chromatography ion trap mass spectrometry
Gaujac, Alain
DMT
Vinho da jurema
Ayahuasca
Multivariate optimization
SPME/GC–MS
title_short Determination of N,N-dimethyltryptamine in beverages consumed in religious practices by headspace solid-phase microextraction followed by gas chromatography ion trap mass spectrometry
title_full Determination of N,N-dimethyltryptamine in beverages consumed in religious practices by headspace solid-phase microextraction followed by gas chromatography ion trap mass spectrometry
title_fullStr Determination of N,N-dimethyltryptamine in beverages consumed in religious practices by headspace solid-phase microextraction followed by gas chromatography ion trap mass spectrometry
title_full_unstemmed Determination of N,N-dimethyltryptamine in beverages consumed in religious practices by headspace solid-phase microextraction followed by gas chromatography ion trap mass spectrometry
title_sort Determination of N,N-dimethyltryptamine in beverages consumed in religious practices by headspace solid-phase microextraction followed by gas chromatography ion trap mass spectrometry
author Gaujac, Alain
author_facet Gaujac, Alain
Dempster, Nicola M.
Navickiene, Sandro
Brandt, Simon D.
Andrade, Jailson Bittencourt de
author_role author
author2 Dempster, Nicola M.
Navickiene, Sandro
Brandt, Simon D.
Andrade, Jailson Bittencourt de
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Gaujac, Alain
Dempster, Nicola M.
Navickiene, Sandro
Brandt, Simon D.
Andrade, Jailson Bittencourt de
Gaujac, Alain
Dempster, Nicola M.
Navickiene, Sandro
Brandt, Simon D.
Andrade, Jailson Bittencourt de
dc.subject.por.fl_str_mv DMT
Vinho da jurema
Ayahuasca
Multivariate optimization
SPME/GC–MS
topic DMT
Vinho da jurema
Ayahuasca
Multivariate optimization
SPME/GC–MS
description Texto completo: acesso restrito. p. 394–398
publishDate 2013
dc.date.issued.fl_str_mv 2013
dc.date.accessioned.fl_str_mv 2014-12-17T12:01:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/16815
dc.identifier.issn.none.fl_str_mv 0039-9140
dc.identifier.number.pt_BR.fl_str_mv v. 106, n. 15
identifier_str_mv 0039-9140
v. 106, n. 15
url http://repositorio.ufba.br/ri/handle/ri/16815
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/ 10.1016/j.talanta.2013.01.017
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