Effectiveness of laser photobiomodulation at 660 or 780 nanometers on the repair of third-degree burns in diabetic rats

Detalhes bibliográficos
Autor(a) principal: Meireles, Gyselle Cynthia Silva
Data de Publicação: 2008
Outros Autores: Santos, Jean Nunes dos, Chagas, Priscila O., Moura, Adriana P., Pinheiro, Antonio Luiz Barbosa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/15256
Resumo: Texto completo: acesso restrito. p. 47-54
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spelling Meireles, Gyselle Cynthia SilvaSantos, Jean Nunes dosChagas, Priscila O.Moura, Adriana P.Pinheiro, Antonio Luiz BarbosaMeireles, Gyselle Cynthia SilvaSantos, Jean Nunes dosChagas, Priscila O.Moura, Adriana P.Pinheiro, Antonio Luiz Barbosa2014-07-22T13:52:46Z20081549-5418http://repositorio.ufba.br/ri/handle/ri/15256v. 26, n. 1Texto completo: acesso restrito. p. 47-54Objective: The aim of this investigation was to compare by light microscopy the effects of laser photobiomodulation (LPBM) at λ = 660 nm and λ = 780 nm on third-degree burns in diabetic Wistar rats. Background Data: Burns are severe injuries that result in fluid loss, tissue destruction, infection, and shock, that may result in death. Diabetes is a disease that reduces the body's ability to heal properly. LPBM has been suggested as an effective method of improving wound healing. Materials and Methods: A third-degree burn measuring 1.5 × 1.5 cm was created in the dorsum of each of 55 animals, and they were divided into three groups that were or were not treated with LPBM (λ = 660 nm or λ = 780 nm, 35 mW, = ˜ 2 mm, 20 J/cm2). The treatments were started immediately post-burn at four points within the burned area (5 J/cm2) and were repeated at 24-hour intervals over 21 d. The animals were humanely killed after 3, 5, 7, 14, and 21 d by an overdose of intraperitoneal general anesthetic. The specimens were routinely cut and stained and analyzed by light microscopy. Results: We found that healing in the animals receiving 660-nm laser energy was more apparent at early stages, with positive effects on inflammation, the amount and quality of granulation tissue, fibroblast proliferation, and on collagen deposition and organization. Epithelialization and local microcirculation were also positively affected by the treatment. Conclusion: The use of 780-nm laser energy was not as effective as 660-nm energy, but it had positive effects at early stages on the onset and development of inflammation. At the end of the experimental period the primary effect seen was on the amount and quality of the granulation tissue. The 660-nm laser at 20 J/cm2, when used on a daily basis, was more effective than the 780-nm laser for improving the healing of third-degree burns in the diabetic rats beginning at the early stages post-burn.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-12-16T15:27:52Z No. of bitstreams: 1 pho%2E2007%2E2051.pdf: 4194304 bytes, checksum: 5a0e18c916185fac8842c57d163098d6 (MD5)Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2014-07-22T13:52:46Z (GMT) No. of bitstreams: 1 pho%2E2007%2E2051.pdf: 4194304 bytes, checksum: 5a0e18c916185fac8842c57d163098d6 (MD5)Made available in DSpace on 2014-07-22T13:52:46Z (GMT). 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dc.title.pt_BR.fl_str_mv Effectiveness of laser photobiomodulation at 660 or 780 nanometers on the repair of third-degree burns in diabetic rats
dc.title.alternative.pt_BR.fl_str_mv Photomedicine and Laser Surgery
title Effectiveness of laser photobiomodulation at 660 or 780 nanometers on the repair of third-degree burns in diabetic rats
spellingShingle Effectiveness of laser photobiomodulation at 660 or 780 nanometers on the repair of third-degree burns in diabetic rats
Meireles, Gyselle Cynthia Silva
Diabetic
Photobiomodulation
title_short Effectiveness of laser photobiomodulation at 660 or 780 nanometers on the repair of third-degree burns in diabetic rats
title_full Effectiveness of laser photobiomodulation at 660 or 780 nanometers on the repair of third-degree burns in diabetic rats
title_fullStr Effectiveness of laser photobiomodulation at 660 or 780 nanometers on the repair of third-degree burns in diabetic rats
title_full_unstemmed Effectiveness of laser photobiomodulation at 660 or 780 nanometers on the repair of third-degree burns in diabetic rats
title_sort Effectiveness of laser photobiomodulation at 660 or 780 nanometers on the repair of third-degree burns in diabetic rats
author Meireles, Gyselle Cynthia Silva
author_facet Meireles, Gyselle Cynthia Silva
Santos, Jean Nunes dos
Chagas, Priscila O.
Moura, Adriana P.
Pinheiro, Antonio Luiz Barbosa
author_role author
author2 Santos, Jean Nunes dos
Chagas, Priscila O.
Moura, Adriana P.
Pinheiro, Antonio Luiz Barbosa
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Meireles, Gyselle Cynthia Silva
Santos, Jean Nunes dos
Chagas, Priscila O.
Moura, Adriana P.
Pinheiro, Antonio Luiz Barbosa
Meireles, Gyselle Cynthia Silva
Santos, Jean Nunes dos
Chagas, Priscila O.
Moura, Adriana P.
Pinheiro, Antonio Luiz Barbosa
dc.subject.por.fl_str_mv Diabetic
Photobiomodulation
topic Diabetic
Photobiomodulation
description Texto completo: acesso restrito. p. 47-54
publishDate 2008
dc.date.issued.fl_str_mv 2008
dc.date.accessioned.fl_str_mv 2014-07-22T13:52:46Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/15256
dc.identifier.issn.none.fl_str_mv 1549-5418
dc.identifier.number.pt_BR.fl_str_mv v. 26, n. 1
identifier_str_mv 1549-5418
v. 26, n. 1
url http://repositorio.ufba.br/ri/handle/ri/15256
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1089/pho.2007.2051.
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