Common mental disorders associated with tuberculosis: a matched case-control study

Detalhes bibliográficos
Autor(a) principal: Araújo, Gleide Santos de
Data de Publicação: 2014
Outros Autores: Pereira, Susan Martins, Santos, Darci Neves dos, Marinho, Jamocyr Moura, Rodrigues, Laura Cunha, Barreto, Mauricio Lima
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/17880
Resumo: INTRODUCTION: Despite the availability of treatment and a vaccine, tuberculosis continues to be a public health problem worldwide. Mental disorders might contribute to the burden of the disease. OBJECTIVE: The objective of this study was to investigate the association between common mental disorders and tuberculosis. METHODS: A matched case-control study was conducted. The study population included symptomatic respiratory patients who attended three referral hospitals and six community clinics in the city of Salvador, Brazil. A doctor's diagnosis defined potential cases and controls. Cases were newly diagnosed tuberculosis cases, and controls were symptomatic respiratory patients for whom tuberculosis was excluded as a diagnosis by the attending physician. Cases and controls were ascertained in the same clinic. Data collection occurred between August 2008 and April 2010. The study instruments included a structured interview, a self-reporting questionnaire for the identification of common mental disorders, and a questionnaire for alcoholism. An univariate analysis included descriptive procedures (with chi-square statistics), and a multivariate analysis used conditional logistic regression. RESULTS: The mean age of the cases was 38 years, and 61% of the cases were males. After adjusting for potential confounders, the odds of tuberculosis were significantly higher in patients diagnosed with a common mental disorder (OR: 1.34; 95% CI 1.05-1.70). CONCLUSION: There appears to be a positive and independent association between common mental disorders and tuberculosis; further epidemiological studies are required to increase our understanding of the possible biological and social mechanisms responsible for this association. Independent of the direction of the association, this finding has implications for the provision of care for mental disorders and for tuberculosis.
id UFBA-2_3869fad67557f77068a592915b16eb3e
oai_identifier_str oai:repositorio.ufba.br:ri/17880
network_acronym_str UFBA-2
network_name_str Repositório Institucional da UFBA
repository_id_str 1932
spelling Araújo, Gleide Santos dePereira, Susan MartinsSantos, Darci Neves dosMarinho, Jamocyr MouraRodrigues, Laura CunhaBarreto, Mauricio LimaAraújo, Gleide Santos dePereira, Susan MartinsSantos, Darci Neves dosMarinho, Jamocyr MouraRodrigues, Laura CunhaBarreto, Mauricio Lima2015-06-15T13:46:35Z2015-06-15T13:46:35Z20141932-6203http://repositorio.ufba.br/ri/handle/ri/17880PLoS One, v.9, n.6, p.e99551.INTRODUCTION: Despite the availability of treatment and a vaccine, tuberculosis continues to be a public health problem worldwide. Mental disorders might contribute to the burden of the disease. OBJECTIVE: The objective of this study was to investigate the association between common mental disorders and tuberculosis. METHODS: A matched case-control study was conducted. The study population included symptomatic respiratory patients who attended three referral hospitals and six community clinics in the city of Salvador, Brazil. A doctor's diagnosis defined potential cases and controls. Cases were newly diagnosed tuberculosis cases, and controls were symptomatic respiratory patients for whom tuberculosis was excluded as a diagnosis by the attending physician. Cases and controls were ascertained in the same clinic. Data collection occurred between August 2008 and April 2010. The study instruments included a structured interview, a self-reporting questionnaire for the identification of common mental disorders, and a questionnaire for alcoholism. An univariate analysis included descriptive procedures (with chi-square statistics), and a multivariate analysis used conditional logistic regression. RESULTS: The mean age of the cases was 38 years, and 61% of the cases were males. After adjusting for potential confounders, the odds of tuberculosis were significantly higher in patients diagnosed with a common mental disorder (OR: 1.34; 95% CI 1.05-1.70). CONCLUSION: There appears to be a positive and independent association between common mental disorders and tuberculosis; further epidemiological studies are required to increase our understanding of the possible biological and social mechanisms responsible for this association. Independent of the direction of the association, this finding has implications for the provision of care for mental disorders and for tuberculosis.Submitted by Maria Creuza Silva (mariakreuza@yahoo.com.br) on 2015-06-15T13:46:35Z No. of bitstreams: 1 Santos Darci. 2014 et al.pdf: 184108 bytes, checksum: efe395c3ae5f3394885f78dd6758071d (MD5)Made available in DSpace on 2015-06-15T13:46:35Z (GMT). No. of bitstreams: 1 Santos Darci. 2014 et al.pdf: 184108 bytes, checksum: efe395c3ae5f3394885f78dd6758071d (MD5) Previous issue date: 2014San FranciscoPublic Library of ScienceBrasilMental DisordersTuberculosisAssociation Between Common Mental DisordersCommon mental disorders associated with tuberculosis: a matched case-control studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessengreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAORIGINALSantos Darci. 2014 et al.pdfSantos Darci. 2014 et al.pdfapplication/pdf184108https://repositorio.ufba.br/bitstream/ri/17880/1/Santos%20Darci.%202014%20et%20al.pdfefe395c3ae5f3394885f78dd6758071dMD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/17880/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXTSantos Darci. 2014 et al.pdf.txtSantos Darci. 2014 et al.pdf.txtExtracted texttext/plain26009https://repositorio.ufba.br/bitstream/ri/17880/3/Santos%20Darci.%202014%20et%20al.pdf.txtf3d4c479f79bfecd6066d6bf5bbd0701MD53ri/178802022-08-08 13:17:33.1oai:repositorio.ufba.br:ri/17880VGVybW8gZGUgTGljZW7vv71hLCBu77+9byBleGNsdXNpdm8sIHBhcmEgbyBkZXDvv71zaXRvIG5vIFJlcG9zaXTvv71yaW8gSW5zdGl0dWNpb25hbCBkYSBVRkJBLgoKIFBlbG8gcHJvY2Vzc28gZGUgc3VibWlzc++/vW8gZGUgZG9jdW1lbnRvcywgbyBhdXRvciBvdSBzZXUgcmVwcmVzZW50YW50ZSBsZWdhbCwgYW8gYWNlaXRhciAKZXNzZSB0ZXJtbyBkZSBsaWNlbu+/vWEsIGNvbmNlZGUgYW8gUmVwb3NpdO+/vXJpbyBJbnN0aXR1Y2lvbmFsIGRhIFVuaXZlcnNpZGFkZSBGZWRlcmFsIGRhIEJhaGlhIApvIGRpcmVpdG8gZGUgbWFudGVyIHVtYSBj77+9cGlhIGVtIHNldSByZXBvc2l077+9cmlvIGNvbSBhIGZpbmFsaWRhZGUsIHByaW1laXJhLCBkZSBwcmVzZXJ2Ye+/ve+/vW8uIApFc3NlcyB0ZXJtb3MsIG7vv71vIGV4Y2x1c2l2b3MsIG1hbnTvv71tIG9zIGRpcmVpdG9zIGRlIGF1dG9yL2NvcHlyaWdodCwgbWFzIGVudGVuZGUgbyBkb2N1bWVudG8gCmNvbW8gcGFydGUgZG8gYWNlcnZvIGludGVsZWN0dWFsIGRlc3NhIFVuaXZlcnNpZGFkZS4KCiBQYXJhIG9zIGRvY3VtZW50b3MgcHVibGljYWRvcyBjb20gcmVwYXNzZSBkZSBkaXJlaXRvcyBkZSBkaXN0cmlidWnvv73vv71vLCBlc3NlIHRlcm1vIGRlIGxpY2Vu77+9YSAKZW50ZW5kZSBxdWU6CgogTWFudGVuZG8gb3MgZGlyZWl0b3MgYXV0b3JhaXMsIHJlcGFzc2Fkb3MgYSB0ZXJjZWlyb3MsIGVtIGNhc28gZGUgcHVibGljYe+/ve+/vWVzLCBvIHJlcG9zaXTvv71yaW8KcG9kZSByZXN0cmluZ2lyIG8gYWNlc3NvIGFvIHRleHRvIGludGVncmFsLCBtYXMgbGliZXJhIGFzIGluZm9ybWHvv73vv71lcyBzb2JyZSBvIGRvY3VtZW50bwooTWV0YWRhZG9zIGVzY3JpdGl2b3MpLgoKIERlc3RhIGZvcm1hLCBhdGVuZGVuZG8gYW9zIGFuc2Vpb3MgZGVzc2EgdW5pdmVyc2lkYWRlIGVtIG1hbnRlciBzdWEgcHJvZHXvv73vv71vIGNpZW5077+9ZmljYSBjb20gCmFzIHJlc3Ryae+/ve+/vWVzIGltcG9zdGFzIHBlbG9zIGVkaXRvcmVzIGRlIHBlcmnvv71kaWNvcy4KCiBQYXJhIGFzIHB1YmxpY2Hvv73vv71lcyBzZW0gaW5pY2lhdGl2YXMgcXVlIHNlZ3VlbSBhIHBvbO+/vXRpY2EgZGUgQWNlc3NvIEFiZXJ0bywgb3MgZGVw77+9c2l0b3MgCmNvbXB1bHPvv71yaW9zIG5lc3NlIHJlcG9zaXTvv71yaW8gbWFudO+/vW0gb3MgZGlyZWl0b3MgYXV0b3JhaXMsIG1hcyBtYW5077+9bSBhY2Vzc28gaXJyZXN0cml0byAKYW8gbWV0YWRhZG9zIGUgdGV4dG8gY29tcGxldG8uIEFzc2ltLCBhIGFjZWl0Ye+/ve+/vW8gZGVzc2UgdGVybW8gbu+/vW8gbmVjZXNzaXRhIGRlIGNvbnNlbnRpbWVudG8KIHBvciBwYXJ0ZSBkZSBhdXRvcmVzL2RldGVudG9yZXMgZG9zIGRpcmVpdG9zLCBwb3IgZXN0YXJlbSBlbSBpbmljaWF0aXZhcyBkZSBhY2Vzc28gYWJlcnRvLgo=Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-08-08T16:17:33Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Common mental disorders associated with tuberculosis: a matched case-control study
title Common mental disorders associated with tuberculosis: a matched case-control study
spellingShingle Common mental disorders associated with tuberculosis: a matched case-control study
Araújo, Gleide Santos de
Mental Disorders
Tuberculosis
Association Between Common Mental Disorders
title_short Common mental disorders associated with tuberculosis: a matched case-control study
title_full Common mental disorders associated with tuberculosis: a matched case-control study
title_fullStr Common mental disorders associated with tuberculosis: a matched case-control study
title_full_unstemmed Common mental disorders associated with tuberculosis: a matched case-control study
title_sort Common mental disorders associated with tuberculosis: a matched case-control study
author Araújo, Gleide Santos de
author_facet Araújo, Gleide Santos de
Pereira, Susan Martins
Santos, Darci Neves dos
Marinho, Jamocyr Moura
Rodrigues, Laura Cunha
Barreto, Mauricio Lima
author_role author
author2 Pereira, Susan Martins
Santos, Darci Neves dos
Marinho, Jamocyr Moura
Rodrigues, Laura Cunha
Barreto, Mauricio Lima
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Araújo, Gleide Santos de
Pereira, Susan Martins
Santos, Darci Neves dos
Marinho, Jamocyr Moura
Rodrigues, Laura Cunha
Barreto, Mauricio Lima
Araújo, Gleide Santos de
Pereira, Susan Martins
Santos, Darci Neves dos
Marinho, Jamocyr Moura
Rodrigues, Laura Cunha
Barreto, Mauricio Lima
dc.subject.por.fl_str_mv Mental Disorders
Tuberculosis
Association Between Common Mental Disorders
topic Mental Disorders
Tuberculosis
Association Between Common Mental Disorders
description INTRODUCTION: Despite the availability of treatment and a vaccine, tuberculosis continues to be a public health problem worldwide. Mental disorders might contribute to the burden of the disease. OBJECTIVE: The objective of this study was to investigate the association between common mental disorders and tuberculosis. METHODS: A matched case-control study was conducted. The study population included symptomatic respiratory patients who attended three referral hospitals and six community clinics in the city of Salvador, Brazil. A doctor's diagnosis defined potential cases and controls. Cases were newly diagnosed tuberculosis cases, and controls were symptomatic respiratory patients for whom tuberculosis was excluded as a diagnosis by the attending physician. Cases and controls were ascertained in the same clinic. Data collection occurred between August 2008 and April 2010. The study instruments included a structured interview, a self-reporting questionnaire for the identification of common mental disorders, and a questionnaire for alcoholism. An univariate analysis included descriptive procedures (with chi-square statistics), and a multivariate analysis used conditional logistic regression. RESULTS: The mean age of the cases was 38 years, and 61% of the cases were males. After adjusting for potential confounders, the odds of tuberculosis were significantly higher in patients diagnosed with a common mental disorder (OR: 1.34; 95% CI 1.05-1.70). CONCLUSION: There appears to be a positive and independent association between common mental disorders and tuberculosis; further epidemiological studies are required to increase our understanding of the possible biological and social mechanisms responsible for this association. Independent of the direction of the association, this finding has implications for the provision of care for mental disorders and for tuberculosis.
publishDate 2014
dc.date.issued.fl_str_mv 2014
dc.date.accessioned.fl_str_mv 2015-06-15T13:46:35Z
dc.date.available.fl_str_mv 2015-06-15T13:46:35Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/17880
dc.identifier.issn.none.fl_str_mv 1932-6203
dc.identifier.number.pt_BR.fl_str_mv PLoS One, v.9, n.6, p.e99551.
identifier_str_mv 1932-6203
PLoS One, v.9, n.6, p.e99551.
url http://repositorio.ufba.br/ri/handle/ri/17880
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Public Library of Science
dc.publisher.country.fl_str_mv Brasil
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
bitstream.url.fl_str_mv https://repositorio.ufba.br/bitstream/ri/17880/1/Santos%20Darci.%202014%20et%20al.pdf
https://repositorio.ufba.br/bitstream/ri/17880/2/license.txt
https://repositorio.ufba.br/bitstream/ri/17880/3/Santos%20Darci.%202014%20et%20al.pdf.txt
bitstream.checksum.fl_str_mv efe395c3ae5f3394885f78dd6758071d
ff6eaa8b858ea317fded99f125f5fcd0
f3d4c479f79bfecd6066d6bf5bbd0701
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)
repository.mail.fl_str_mv
_version_ 1801502561208893440