Prolactin secretion in hypothyroid endotoxemic rats: involvement of l-arginine and Nitric Oxide synthase

Detalhes bibliográficos
Autor(a) principal: Rodriguez, Tânia Tavares
Data de Publicação: 2005
Outros Autores: Biscarde, Eduardo Ferreira da Silva, Muniz, Relva de Freitas Diniz Goncalves, Amoedo, Maurício Kauark, Ramalho, Maria José Pedreira
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/13895
Resumo: Texto completo: acesso restrito. p. 448-452
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spelling Rodriguez, Tânia TavaresBiscarde, Eduardo Ferreira da SilvaMuniz, Relva de Freitas Diniz GoncalvesAmoedo, Maurício KauarkRamalho, Maria José PedreiraRodriguez, Tânia TavaresBiscarde, Eduardo Ferreira da SilvaMuniz, Relva de Freitas Diniz GoncalvesAmoedo, Maurício KauarkRamalho, Maria José Pedreira2013-11-26T12:59:53Z20051073-2322http://repositorio.ufba.br/ri/handle/ri/13895v. 23, n. 5Texto completo: acesso restrito. p. 448-452The identification of nitric oxide (NO) within the hypothalamus and pituitary gland has suggested its role as modulator of the activity on hypothalamic-pituitary axis. Hypothalamic NO synthase (NOS) is known to be regulated by thyroid hormones. We investigated the effects of previous injection of N[omega pi]-nitro-L-arginine methyl ester (L-NAME), a NOS inhibitor, and L-arginine (L-Arg), the substrate for NO synthesis, on prolactin (PRL) secretion, through the lipopolysaccharide (LPS)-induced inflammatory response in thyroidectomized (TX) rats. TX or sham-operated (N) rats were intraperitoneally (i.p.) injected with L-NAME (10 mg kg-1) or L-Arg (200 mg kg-1) or the same volume of vehicle (saline solution) 30 min before endotoxemia-induction with LPS at 250 µg (100 g body weight)-1, i.p.. In N rats, NO increased PRL release in response to endotoxemia, whereas in hypothyroid rats, NO appeared to have the opposite effect. Our data support the hypothesis that NO exerts a modulatory influence on PRL secretion after LPS-induced inflammatory response.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2013-11-26T11:50:37Z No. of bitstreams: 1 Rodriguez, Tania.pdf: 195769 bytes, checksum: e25f4386f1358443a4bf1db8291dccc0 (MD5)Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2013-11-26T12:59:53Z (GMT) No. of bitstreams: 1 Rodriguez, Tania.pdf: 195769 bytes, checksum: e25f4386f1358443a4bf1db8291dccc0 (MD5)Made available in DSpace on 2013-11-26T12:59:53Z (GMT). No. of bitstreams: 1 Rodriguez, Tania.pdf: 195769 bytes, checksum: e25f4386f1358443a4bf1db8291dccc0 (MD5) Previous issue date: 2005LipopolysaccharideL-NAMEL-arginineHyroidectomyEndotoxemiaProlactinProlactin secretion in hypothyroid endotoxemic rats: involvement of l-arginine and Nitric Oxide synthaseShockinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAORIGINALRodriguez, Tania.pdfRodriguez, Tania.pdfapplication/pdf195769https://repositorio.ufba.br/bitstream/ri/13895/1/Rodriguez%2c%20Tania.pdfe25f4386f1358443a4bf1db8291dccc0MD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/13895/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXTRodriguez, Tania.pdf.txtRodriguez, Tania.pdf.txtExtracted texttext/plain25209https://repositorio.ufba.br/bitstream/ri/13895/3/Rodriguez%2c%20Tania.pdf.txt962414d7ea16e2ae631814be34839047MD53ri/138952022-07-05 14:03:01.916oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:01Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Prolactin secretion in hypothyroid endotoxemic rats: involvement of l-arginine and Nitric Oxide synthase
dc.title.alternative.pt_BR.fl_str_mv Shock
title Prolactin secretion in hypothyroid endotoxemic rats: involvement of l-arginine and Nitric Oxide synthase
spellingShingle Prolactin secretion in hypothyroid endotoxemic rats: involvement of l-arginine and Nitric Oxide synthase
Rodriguez, Tânia Tavares
Lipopolysaccharide
L-NAME
L-arginine
Hyroidectomy
Endotoxemia
Prolactin
title_short Prolactin secretion in hypothyroid endotoxemic rats: involvement of l-arginine and Nitric Oxide synthase
title_full Prolactin secretion in hypothyroid endotoxemic rats: involvement of l-arginine and Nitric Oxide synthase
title_fullStr Prolactin secretion in hypothyroid endotoxemic rats: involvement of l-arginine and Nitric Oxide synthase
title_full_unstemmed Prolactin secretion in hypothyroid endotoxemic rats: involvement of l-arginine and Nitric Oxide synthase
title_sort Prolactin secretion in hypothyroid endotoxemic rats: involvement of l-arginine and Nitric Oxide synthase
author Rodriguez, Tânia Tavares
author_facet Rodriguez, Tânia Tavares
Biscarde, Eduardo Ferreira da Silva
Muniz, Relva de Freitas Diniz Goncalves
Amoedo, Maurício Kauark
Ramalho, Maria José Pedreira
author_role author
author2 Biscarde, Eduardo Ferreira da Silva
Muniz, Relva de Freitas Diniz Goncalves
Amoedo, Maurício Kauark
Ramalho, Maria José Pedreira
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Rodriguez, Tânia Tavares
Biscarde, Eduardo Ferreira da Silva
Muniz, Relva de Freitas Diniz Goncalves
Amoedo, Maurício Kauark
Ramalho, Maria José Pedreira
Rodriguez, Tânia Tavares
Biscarde, Eduardo Ferreira da Silva
Muniz, Relva de Freitas Diniz Goncalves
Amoedo, Maurício Kauark
Ramalho, Maria José Pedreira
dc.subject.por.fl_str_mv Lipopolysaccharide
L-NAME
L-arginine
Hyroidectomy
Endotoxemia
Prolactin
topic Lipopolysaccharide
L-NAME
L-arginine
Hyroidectomy
Endotoxemia
Prolactin
description Texto completo: acesso restrito. p. 448-452
publishDate 2005
dc.date.issued.fl_str_mv 2005
dc.date.accessioned.fl_str_mv 2013-11-26T12:59:53Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/13895
dc.identifier.issn.none.fl_str_mv 1073-2322
dc.identifier.number.pt_BR.fl_str_mv v. 23, n. 5
identifier_str_mv 1073-2322
v. 23, n. 5
url http://repositorio.ufba.br/ri/handle/ri/13895
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
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instacron_str UFBA
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reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
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