Comparative Analysis of Severe Pediatric and Adult Leptospirosis in São Paulo, Brazil

Detalhes bibliográficos
Autor(a) principal: Spichler, Anne Stambovsky
Data de Publicação: 2012
Outros Autores: Athanazio, Daniel Abensur, Vilaça, Pedro, Seguro, Antônio Carlos, Vinetz, Joseph M., Leake, John A. D.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/16082
Resumo: Texto completo: acesso restrito. p. 306-308
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spelling Spichler, Anne StambovskyAthanazio, Daniel AbensurVilaça, PedroSeguro, Antônio CarlosVinetz, Joseph M.Leake, John A. D.Spichler, Anne StambovskyAthanazio, Daniel AbensurVilaça, PedroSeguro, Antônio CarlosVinetz, Joseph M.Leake, John A. D.2014-09-15T16:01:54Z20120002-9637http://repositorio.ufba.br/ri/handle/ri/16082v. 86, n. 2Texto completo: acesso restrito. p. 306-308Although leptospirosis may be fatal in childhood, the experience of many clinicians working in disease-endemic areas is that classic Weil's disease and death are less common among pediatric patients. The aim of the study was to ascertain disease spectrum and outcome differences in severe pediatric and adult leptospirosis in a large at-risk population. Epidemiologic, clinical, and laboratory data were obtained on hospitalized cases from São Paulo during 2004–2006. A total of 42 case-patients < 18 years of age and 328 case-patients ≥ 18 years of age were tested during the study. Compared with children, adults had higher rates of jaundice (P = 0.01), elevated serum bilirubin levels (P < 0.01), oliguria (P = 0.02), and elevated creatinine levels (P = 0.01) but not for thrombocytopenia or pulmonary involvement. The overall case-fatality rate was 27% (adult) versus 5% (pediatric) (P < 0.01). Severe pediatric leptospirosis may be less likely to show all classic features of Weil's disease and may be less fatal than in adults.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-08-26T12:23:53Z No. of bitstreams: 1 Anne Spichler.pdf: 442392 bytes, checksum: 56015bffe4045fdf28bbd850e83285f1 (MD5)Approved for entry into archive by Delba Rosa (delba@ufba.br) on 2014-09-15T16:01:54Z (GMT) No. of bitstreams: 1 Anne Spichler.pdf: 442392 bytes, checksum: 56015bffe4045fdf28bbd850e83285f1 (MD5)Made available in DSpace on 2014-09-15T16:01:54Z (GMT). No. of bitstreams: 1 Anne Spichler.pdf: 442392 bytes, checksum: 56015bffe4045fdf28bbd850e83285f1 (MD5) Previous issue date: 2012http://dx.doi.org/ 10.4269/ajtmh.2012.11-0308reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAComparative Analysis of Severe Pediatric and Adult Leptospirosis in São Paulo, BrazilAmerican Journal of Tropical Medicine and Hygieneinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALAnne Spichler.pdfAnne Spichler.pdfapplication/pdf442392https://repositorio.ufba.br/bitstream/ri/16082/1/Anne%20Spichler.pdf56015bffe4045fdf28bbd850e83285f1MD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/16082/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXTAnne Spichler.pdf.txtAnne Spichler.pdf.txtExtracted texttext/plain15573https://repositorio.ufba.br/bitstream/ri/16082/3/Anne%20Spichler.pdf.txtfaa94091047768d578c98db97be8f866MD53ri/160822022-07-05 14:02:59.272oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:02:59Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Comparative Analysis of Severe Pediatric and Adult Leptospirosis in São Paulo, Brazil
dc.title.alternative.pt_BR.fl_str_mv American Journal of Tropical Medicine and Hygiene
title Comparative Analysis of Severe Pediatric and Adult Leptospirosis in São Paulo, Brazil
spellingShingle Comparative Analysis of Severe Pediatric and Adult Leptospirosis in São Paulo, Brazil
Spichler, Anne Stambovsky
title_short Comparative Analysis of Severe Pediatric and Adult Leptospirosis in São Paulo, Brazil
title_full Comparative Analysis of Severe Pediatric and Adult Leptospirosis in São Paulo, Brazil
title_fullStr Comparative Analysis of Severe Pediatric and Adult Leptospirosis in São Paulo, Brazil
title_full_unstemmed Comparative Analysis of Severe Pediatric and Adult Leptospirosis in São Paulo, Brazil
title_sort Comparative Analysis of Severe Pediatric and Adult Leptospirosis in São Paulo, Brazil
author Spichler, Anne Stambovsky
author_facet Spichler, Anne Stambovsky
Athanazio, Daniel Abensur
Vilaça, Pedro
Seguro, Antônio Carlos
Vinetz, Joseph M.
Leake, John A. D.
author_role author
author2 Athanazio, Daniel Abensur
Vilaça, Pedro
Seguro, Antônio Carlos
Vinetz, Joseph M.
Leake, John A. D.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Spichler, Anne Stambovsky
Athanazio, Daniel Abensur
Vilaça, Pedro
Seguro, Antônio Carlos
Vinetz, Joseph M.
Leake, John A. D.
Spichler, Anne Stambovsky
Athanazio, Daniel Abensur
Vilaça, Pedro
Seguro, Antônio Carlos
Vinetz, Joseph M.
Leake, John A. D.
description Texto completo: acesso restrito. p. 306-308
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2014-09-15T16:01:54Z
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dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/16082
dc.identifier.issn.none.fl_str_mv 0002-9637
dc.identifier.number.pt_BR.fl_str_mv v. 86, n. 2
identifier_str_mv 0002-9637
v. 86, n. 2
url http://repositorio.ufba.br/ri/handle/ri/16082
dc.language.iso.fl_str_mv eng
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