Season of birth as a risk factor for multiple sclerosis in Brazil
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2013 |
| Outros Autores: | , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFBA |
| Texto Completo: | http://repositorio.ufba.br/ri/handle/ri/13395 |
Resumo: | p. 6–10 |
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Becker, JeffersonCallegaro, DagobertoLana-Peixoto, Marco AurélioFerreira, Maria Lúcia B.Melo, Ailton de SouzaGama, Paulo Diniz daSouza, Doralina G. B.Teixeira, Carlos A. C.Kaimen-Maciel, Damacio RamónGonçalves, Marcus ViníciusMatta, André P. C.Abraham, RonaldoFurtado, Luís Edmundo T. A.Lino, AngelinaHauck, LauraBarreira, Amilton AntunesGomes, IrenioBecker, JeffersonCallegaro, DagobertoLana-Peixoto, Marco AurélioFerreira, Maria Lúcia B.Melo, Ailton de SouzaGama, Paulo Diniz daSouza, Doralina G. B.Teixeira, Carlos A. C.Kaimen-Maciel, Damacio RamónGonçalves, Marcus ViníciusMatta, André P. C.Abraham, RonaldoFurtado, Luís Edmundo T. A.Lino, AngelinaHauck, LauraBarreira, Amilton AntunesGomes, Irenio2013-10-31T17:36:47Z20130022-510Xhttp://repositorio.ufba.br/ri/handle/ri/13395v. 329, n. 1–2p. 6–10Risk factors for development of multiple sclerosis (MS) are still a matter of debate. Latitude gradient, vitamin D deficiency and season of birth are among the most investigated environmental factors associated with the disease. Several international studies suggest that birth in spring is a substantial risk factor for MS. We investigated the season of birth as a potential risk for MS in different geographical regions of Brazil. We conducted a cross-sectional retrospective study with 2257 clinically definite MS patients enrolled in 13 Brazilian MS clinics in the south, southeast, and northeast regions of Brazil. Demographic and clinical data relating to date of birth and clinical features of the disease were collected and analysed, and subsequently compared with birth date among the general Brazilian population. The distribution of date of birth of MS patients showed an increase in spring and a decrease in autumn, with no difference being observed in the other seasons. In conclusion, season of birth is a probable risk factor for MS in most parts of Brazil. These findings may be related to the role that vitamin D plays in MS pathogenesis.Submitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2013-10-30T19:34:28Z No. of bitstreams: 1 444444.pdf: 615700 bytes, checksum: fb343d0ce8c37f1b4a108bb5081c14cc (MD5)Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2013-10-31T17:36:47Z (GMT) No. of bitstreams: 1 444444.pdf: 615700 bytes, checksum: fb343d0ce8c37f1b4a108bb5081c14cc (MD5)Made available in DSpace on 2013-10-31T17:36:47Z (GMT). No. of bitstreams: 1 444444.pdf: 615700 bytes, checksum: fb343d0ce8c37f1b4a108bb5081c14cc (MD5) Previous issue date: 2013SalvadorJournal of the Neurological Scienceshttp://www.sciencedirect.com/science/article/pii/S0022510X1300107Xreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBASeason of birthMonth of birthRisk factorMultiple sclerosisVitamin DMS epidemiologySeason of birth as a risk factor for multiple sclerosis in BrazilJournal of the Neurological Sciencesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINAL444444.pdf444444.pdfapplication/pdf615700https://repositorio.ufba.br/bitstream/ri/13395/1/444444.pdffb343d0ce8c37f1b4a108bb5081c14ccMD51LICENSElicense.txtlicense.txttext/plain1383https://repositorio.ufba.br/bitstream/ri/13395/2/license.txt05eca2f01d0b3307819d0369dab18a34MD52TEXT444444.pdf.txt444444.pdf.txtExtracted texttext/plain25057https://repositorio.ufba.br/bitstream/ri/13395/3/444444.pdf.txt3107851e524ced7e35ff0c1be70709e5MD53ri/133952022-07-05 14:03:09.85oai:repositorio.ufba.br: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ório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:09Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
| dc.title.pt_BR.fl_str_mv |
Season of birth as a risk factor for multiple sclerosis in Brazil |
| dc.title.alternative.pt_BR.fl_str_mv |
Journal of the Neurological Sciences |
| title |
Season of birth as a risk factor for multiple sclerosis in Brazil |
| spellingShingle |
Season of birth as a risk factor for multiple sclerosis in Brazil Becker, Jefferson Season of birth Month of birth Risk factor Multiple sclerosis Vitamin D MS epidemiology |
| title_short |
Season of birth as a risk factor for multiple sclerosis in Brazil |
| title_full |
Season of birth as a risk factor for multiple sclerosis in Brazil |
| title_fullStr |
Season of birth as a risk factor for multiple sclerosis in Brazil |
| title_full_unstemmed |
Season of birth as a risk factor for multiple sclerosis in Brazil |
| title_sort |
Season of birth as a risk factor for multiple sclerosis in Brazil |
| author |
Becker, Jefferson |
| author_facet |
Becker, Jefferson Callegaro, Dagoberto Lana-Peixoto, Marco Aurélio Ferreira, Maria Lúcia B. Melo, Ailton de Souza Gama, Paulo Diniz da Souza, Doralina G. B. Teixeira, Carlos A. C. Kaimen-Maciel, Damacio Ramón Gonçalves, Marcus Vinícius Matta, André P. C. Abraham, Ronaldo Furtado, Luís Edmundo T. A. Lino, Angelina Hauck, Laura Barreira, Amilton Antunes Gomes, Irenio |
| author_role |
author |
| author2 |
Callegaro, Dagoberto Lana-Peixoto, Marco Aurélio Ferreira, Maria Lúcia B. Melo, Ailton de Souza Gama, Paulo Diniz da Souza, Doralina G. B. Teixeira, Carlos A. C. Kaimen-Maciel, Damacio Ramón Gonçalves, Marcus Vinícius Matta, André P. C. Abraham, Ronaldo Furtado, Luís Edmundo T. A. Lino, Angelina Hauck, Laura Barreira, Amilton Antunes Gomes, Irenio |
| author2_role |
author author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Becker, Jefferson Callegaro, Dagoberto Lana-Peixoto, Marco Aurélio Ferreira, Maria Lúcia B. Melo, Ailton de Souza Gama, Paulo Diniz da Souza, Doralina G. B. Teixeira, Carlos A. C. Kaimen-Maciel, Damacio Ramón Gonçalves, Marcus Vinícius Matta, André P. C. Abraham, Ronaldo Furtado, Luís Edmundo T. A. Lino, Angelina Hauck, Laura Barreira, Amilton Antunes Gomes, Irenio Becker, Jefferson Callegaro, Dagoberto Lana-Peixoto, Marco Aurélio Ferreira, Maria Lúcia B. Melo, Ailton de Souza Gama, Paulo Diniz da Souza, Doralina G. B. Teixeira, Carlos A. C. Kaimen-Maciel, Damacio Ramón Gonçalves, Marcus Vinícius Matta, André P. C. Abraham, Ronaldo Furtado, Luís Edmundo T. A. Lino, Angelina Hauck, Laura Barreira, Amilton Antunes Gomes, Irenio |
| dc.subject.por.fl_str_mv |
Season of birth Month of birth Risk factor Multiple sclerosis Vitamin D MS epidemiology |
| topic |
Season of birth Month of birth Risk factor Multiple sclerosis Vitamin D MS epidemiology |
| description |
p. 6–10 |
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2013 |
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2013-10-31T17:36:47Z |
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2013 |
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info:eu-repo/semantics/publishedVersion |
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0022-510X |
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v. 329, n. 1–2 |
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0022-510X v. 329, n. 1–2 |
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Journal of the Neurological Sciences |
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Journal of the Neurological Sciences |
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http://www.sciencedirect.com/science/article/pii/S0022510X1300107X |
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reponame:Repositório Institucional da UFBA instname:Universidade Federal da Bahia (UFBA) instacron:UFBA |
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