Domestic swine in a visceral leishmaniasis endemic area produce antibodies against multiple Leishmania infantum antigens but apparently resist to L. infantum infection
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2006 |
| Outros Autores: | , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFBA |
| Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/6523 |
Resumo: | RESTRITO |
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Silva, Evandro MoraesAntunes, Fabiana RodriguesRodrigues, Marcio SilvaJulião, Fred da SilvaLima, Artur Gomes DiasSousa, Valderez Lemos deAlcântara, Adriano Costa deReis, Eliana Almeida GomesNakatani, MariaBadaró, Roberto José da SilvaReis, Mitermayer GalvãoCarvalho, Lain Carlos Pontes deFranke, Carlos RobertoSilva, Evandro MoraesAntunes, Fabiana RodriguesRodrigues, Marcio SilvaJulião, Fred da SilvaLima, Artur Gomes DiasSousa, Valderez Lemos deAlcântara, Adriano Costa deReis, Eliana Almeida GomesNakatani, MariaBadaró, Roberto José da SilvaReis, Mitermayer GalvãoCarvalho, Lain Carlos Pontes deFranke, Carlos Roberto2012-07-31T19:53:28Z2012-07-31T19:53:28Z20060001-706Xhttp://www.repositorio.ufba.br/ri/handle/ri/6523v.98, n.2RESTRITOIn order to investigate whether pigs can be infected by Leishmania infantum, a serological and parasitological study was carried out on swine in the Jequié municipality, Northeast of Brazil. Anti-Leishmania infantum antibodies were detected in 37 out of 92 swine (40.2%), by two different assays: an anti-L. infantum lysate and an anti-K39 recombinant protein ELISA. An experimental study was also carried out to verify the susceptibility of domestic pigs to L. infantum infection. Three sows inoculated with 108 stationary-phase infective L. infantum promastigotes (26% metacyclic promastigotes) per kilogram of body weight produced anti-Leishmania antibodies until the end of the experiment, 11 months later. No parasites, however, could be visualized through optical microscopy of spleen, liver and bone marrow or by in vitro culture of these organs. Homogenates of these organs were also inoculated in hamsters, without producing infection. No Leishmania DNA was detected by polymerase chain reaction (PCR) in sand flies fed on these animals. The results indicate that domestic pigs bitten by L. infantum-infected vectors in the endemic area do not display a full infection pattern, and the positive association in endemic areas between the presence of swine and infection in canines may not be ascribable to the former acting as a parasite reservoir.Submitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2012-07-31T19:53:28Z No. of bitstreams: 1 HH.pdf: 201900 bytes, checksum: 640cdc682dabd16c562ec2fca3832784 (MD5)Made available in DSpace on 2012-07-31T19:53:28Z (GMT). No. of bitstreams: 1 HH.pdf: 201900 bytes, checksum: 640cdc682dabd16c562ec2fca3832784 (MD5) Previous issue date: 2006SalvadorActa Tropicahttp://dx.doi.org/10.1016/j.actatropica.2006.04.002reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAVisceral leishmaniasisPigImmune responseExperimental infectionDomestic swine in a visceral leishmaniasis endemic area produce antibodies against multiple Leishmania infantum antigens but apparently resist to L. infantum infectionActa Tropicainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleenginfo:eu-repo/semantics/openAccessLICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/6523/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52ORIGINALHH.pdfHH.pdfapplication/pdf201900https://repositorio.ufba.br/bitstream/ri/6523/1/HH.pdf640cdc682dabd16c562ec2fca3832784MD51TEXTHH.pdf.txtHH.pdf.txtExtracted texttext/plain29380https://repositorio.ufba.br/bitstream/ri/6523/3/HH.pdf.txt100628ca7a9f2509c288b5dab38b743bMD53ri/65232022-07-05 14:03:37.844oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:37Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
| dc.title.pt_BR.fl_str_mv |
Domestic swine in a visceral leishmaniasis endemic area produce antibodies against multiple Leishmania infantum antigens but apparently resist to L. infantum infection |
| dc.title.alternative.pt_BR.fl_str_mv |
Acta Tropica |
| title |
Domestic swine in a visceral leishmaniasis endemic area produce antibodies against multiple Leishmania infantum antigens but apparently resist to L. infantum infection |
| spellingShingle |
Domestic swine in a visceral leishmaniasis endemic area produce antibodies against multiple Leishmania infantum antigens but apparently resist to L. infantum infection Silva, Evandro Moraes Visceral leishmaniasis Pig Immune response Experimental infection |
| title_short |
Domestic swine in a visceral leishmaniasis endemic area produce antibodies against multiple Leishmania infantum antigens but apparently resist to L. infantum infection |
| title_full |
Domestic swine in a visceral leishmaniasis endemic area produce antibodies against multiple Leishmania infantum antigens but apparently resist to L. infantum infection |
| title_fullStr |
Domestic swine in a visceral leishmaniasis endemic area produce antibodies against multiple Leishmania infantum antigens but apparently resist to L. infantum infection |
| title_full_unstemmed |
Domestic swine in a visceral leishmaniasis endemic area produce antibodies against multiple Leishmania infantum antigens but apparently resist to L. infantum infection |
| title_sort |
Domestic swine in a visceral leishmaniasis endemic area produce antibodies against multiple Leishmania infantum antigens but apparently resist to L. infantum infection |
| author |
Silva, Evandro Moraes |
| author_facet |
Silva, Evandro Moraes Antunes, Fabiana Rodrigues Rodrigues, Marcio Silva Julião, Fred da Silva Lima, Artur Gomes Dias Sousa, Valderez Lemos de Alcântara, Adriano Costa de Reis, Eliana Almeida Gomes Nakatani, Maria Badaró, Roberto José da Silva Reis, Mitermayer Galvão Carvalho, Lain Carlos Pontes de Franke, Carlos Roberto |
| author_role |
author |
| author2 |
Antunes, Fabiana Rodrigues Rodrigues, Marcio Silva Julião, Fred da Silva Lima, Artur Gomes Dias Sousa, Valderez Lemos de Alcântara, Adriano Costa de Reis, Eliana Almeida Gomes Nakatani, Maria Badaró, Roberto José da Silva Reis, Mitermayer Galvão Carvalho, Lain Carlos Pontes de Franke, Carlos Roberto |
| author2_role |
author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Silva, Evandro Moraes Antunes, Fabiana Rodrigues Rodrigues, Marcio Silva Julião, Fred da Silva Lima, Artur Gomes Dias Sousa, Valderez Lemos de Alcântara, Adriano Costa de Reis, Eliana Almeida Gomes Nakatani, Maria Badaró, Roberto José da Silva Reis, Mitermayer Galvão Carvalho, Lain Carlos Pontes de Franke, Carlos Roberto Silva, Evandro Moraes Antunes, Fabiana Rodrigues Rodrigues, Marcio Silva Julião, Fred da Silva Lima, Artur Gomes Dias Sousa, Valderez Lemos de Alcântara, Adriano Costa de Reis, Eliana Almeida Gomes Nakatani, Maria Badaró, Roberto José da Silva Reis, Mitermayer Galvão Carvalho, Lain Carlos Pontes de Franke, Carlos Roberto |
| dc.subject.por.fl_str_mv |
Visceral leishmaniasis Pig Immune response Experimental infection |
| topic |
Visceral leishmaniasis Pig Immune response Experimental infection |
| description |
RESTRITO |
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2006 |
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2006 |
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2012-07-31T19:53:28Z |
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2012-07-31T19:53:28Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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http://www.repositorio.ufba.br/ri/handle/ri/6523 |
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0001-706X |
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v.98, n.2 |
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0001-706X v.98, n.2 |
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Acta Tropica |
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Acta Tropica |
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http://dx.doi.org/10.1016/j.actatropica.2006.04.002 |
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