Etiology of Childhood Community Acquired Pneumonia and Its Implications for Vaccination
Autor(a) principal: | |
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Data de Publicação: | 2001 |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/7010 |
Resumo: | p. 87-97 |
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Carvalho, Cristiana Maria Costa Nascimento deCarvalho, Cristiana Maria Costa Nascimento de2012-10-22T12:59:08Z2012-10-22T12:59:08Z20011413-8670http://www.repositorio.ufba.br/ri/handle/ri/7010v. 5, n. 2p. 87-97Pneumonia is an important cause of morbidity and mortality among children throughout the world. Vaccines are available for some organisms, but they are underutilized and/or still in development. To evaluate the potential impact of vaccines, we review studies in which the etiology of childhood community-acquired pneumonia was recorded. In North America and Europe (9 studies), the etiology of pneumonia was established in 62% of studied children (range 43%-88%) by use of noninvasive specific methods for microbiologic diagnosis. The most often identified agents were S. pneumoniae (22%), respiratory syncytial virus (RSV) (20%), Haemophilus influenzae (7%), and Mycoplasma pneumoniae (15%). In Africa and South America (8 studies), bacteria were recovered from 56% (range 32%-68%) of severely ill children studied by lung aspirate. The most often isolated bacteria were Streptococcus pneumoniae (33%) and Haemophilus influenzae (21%). A high percentage of H. influenzae strains were not serotype b. Throughout the world, children requiring hospitalization were most likely to have infection caused by pneumococcus H. influenzae or RSV. Out patients also had Mycoplasma pneumoniae. Countries in Africa and Asia recorded 2 to 10 times more children with pneumonia (7 to 40/100 annually) than in the USA. Widespread use of pneumococcal and H. influenzae type b conjugate vaccines could reduce the frequency of childhood pneumonia by one-third. Further reduction will require development of non-type b H. influenzae, RSV and M. pneumoniae vaccines. This could result in a > 50% reduction of pneumonia in children. This goal should be sought and achieved as soon as possible.Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2012-10-22T12:59:08Z No. of bitstreams: 1 __www.scielo.br_pdf_bjid_v5n2_a07v05n2.pdf: 158069 bytes, checksum: 7e6a26f22fdd9ff7f42fe85b116057b3 (MD5)Made available in DSpace on 2012-10-22T12:59:08Z (GMT). No. of bitstreams: 1 __www.scielo.br_pdf_bjid_v5n2_a07v05n2.pdf: 158069 bytes, checksum: 7e6a26f22fdd9ff7f42fe85b116057b3 (MD5) Previous issue date: 2001Salvadorhttp://dx.doi.org/10.1590/S1413-86702001000200007reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAcommunity-acquired pneumoniachildrenetiologyvaccineS. pneumoniaerespiratory syncytial virusEtiology of Childhood Community Acquired Pneumonia and Its Implications for VaccinationBrazilian Journal of Infectious Diseasesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleenginfo:eu-repo/semantics/openAccessORIGINAL__www.scielo.br_pdf_bjid_v5n2_a07v05n2.pdf__www.scielo.br_pdf_bjid_v5n2_a07v05n2.pdfapplication/pdf158069https://repositorio.ufba.br/bitstream/ri/7010/1/__www.scielo.br_pdf_bjid_v5n2_a07v05n2.pdf7e6a26f22fdd9ff7f42fe85b116057b3MD51LICENSElicense.txtlicense.txttext/plain1809https://repositorio.ufba.br/bitstream/ri/7010/2/license.txt8bb3e3eb871f5854a9ec419f68651b60MD52TEXT__www.scielo.br_pdf_bjid_v5n2_a07v05n2.pdf.txt__www.scielo.br_pdf_bjid_v5n2_a07v05n2.pdf.txtExtracted texttext/plain35927https://repositorio.ufba.br/bitstream/ri/7010/3/__www.scielo.br_pdf_bjid_v5n2_a07v05n2.pdf.txt59b42a9f6c1f6b96d9027e649847c1d2MD53ri/70102022-07-05 14:03:19.649oai:repositorio.ufba.br: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ório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:19Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
dc.title.pt_BR.fl_str_mv |
Etiology of Childhood Community Acquired Pneumonia and Its Implications for Vaccination |
dc.title.alternative.pt_BR.fl_str_mv |
Brazilian Journal of Infectious Diseases |
title |
Etiology of Childhood Community Acquired Pneumonia and Its Implications for Vaccination |
spellingShingle |
Etiology of Childhood Community Acquired Pneumonia and Its Implications for Vaccination Carvalho, Cristiana Maria Costa Nascimento de community-acquired pneumonia children etiology vaccine S. pneumoniae respiratory syncytial virus |
title_short |
Etiology of Childhood Community Acquired Pneumonia and Its Implications for Vaccination |
title_full |
Etiology of Childhood Community Acquired Pneumonia and Its Implications for Vaccination |
title_fullStr |
Etiology of Childhood Community Acquired Pneumonia and Its Implications for Vaccination |
title_full_unstemmed |
Etiology of Childhood Community Acquired Pneumonia and Its Implications for Vaccination |
title_sort |
Etiology of Childhood Community Acquired Pneumonia and Its Implications for Vaccination |
author |
Carvalho, Cristiana Maria Costa Nascimento de |
author_facet |
Carvalho, Cristiana Maria Costa Nascimento de |
author_role |
author |
dc.contributor.author.fl_str_mv |
Carvalho, Cristiana Maria Costa Nascimento de Carvalho, Cristiana Maria Costa Nascimento de |
dc.subject.por.fl_str_mv |
community-acquired pneumonia children etiology vaccine S. pneumoniae respiratory syncytial virus |
topic |
community-acquired pneumonia children etiology vaccine S. pneumoniae respiratory syncytial virus |
description |
p. 87-97 |
publishDate |
2001 |
dc.date.issued.fl_str_mv |
2001 |
dc.date.accessioned.fl_str_mv |
2012-10-22T12:59:08Z |
dc.date.available.fl_str_mv |
2012-10-22T12:59:08Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
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publishedVersion |
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http://www.repositorio.ufba.br/ri/handle/ri/7010 |
dc.identifier.issn.none.fl_str_mv |
1413-8670 |
dc.identifier.number.pt_BR.fl_str_mv |
v. 5, n. 2 |
identifier_str_mv |
1413-8670 v. 5, n. 2 |
url |
http://www.repositorio.ufba.br/ri/handle/ri/7010 |
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eng |
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eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
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http://dx.doi.org/10.1590/S1413-86702001000200007 |
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