Etiology of Childhood Community Acquired Pneumonia and Its Implications for Vaccination

Detalhes bibliográficos
Autor(a) principal: Carvalho, Cristiana Maria Costa Nascimento de
Data de Publicação: 2001
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/7010
Resumo: p. 87-97
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spelling Carvalho, Cristiana Maria Costa Nascimento deCarvalho, Cristiana Maria Costa Nascimento de2012-10-22T12:59:08Z2012-10-22T12:59:08Z20011413-8670http://www.repositorio.ufba.br/ri/handle/ri/7010v. 5, n. 2p. 87-97Pneumonia is an important cause of morbidity and mortality among children throughout the world. Vaccines are available for some organisms, but they are underutilized and/or still in development. To evaluate the potential impact of vaccines, we review studies in which the etiology of childhood community-acquired pneumonia was recorded. In North America and Europe (9 studies), the etiology of pneumonia was established in 62% of studied children (range 43%-88%) by use of noninvasive specific methods for microbiologic diagnosis. The most often identified agents were S. pneumoniae (22%), respiratory syncytial virus (RSV) (20%), Haemophilus influenzae (7%), and Mycoplasma pneumoniae (15%). In Africa and South America (8 studies), bacteria were recovered from 56% (range 32%-68%) of severely ill children studied by lung aspirate. The most often isolated bacteria were Streptococcus pneumoniae (33%) and Haemophilus influenzae (21%). A high percentage of H. influenzae strains were not serotype b. Throughout the world, children requiring hospitalization were most likely to have infection caused by pneumococcus H. influenzae or RSV. Out patients also had Mycoplasma pneumoniae. Countries in Africa and Asia recorded 2 to 10 times more children with pneumonia (7 to 40/100 annually) than in the USA. Widespread use of pneumococcal and H. influenzae type b conjugate vaccines could reduce the frequency of childhood pneumonia by one-third. Further reduction will require development of non-type b H. influenzae, RSV and M. pneumoniae vaccines. This could result in a > 50% reduction of pneumonia in children. This goal should be sought and achieved as soon as possible.Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2012-10-22T12:59:08Z No. of bitstreams: 1 __www.scielo.br_pdf_bjid_v5n2_a07v05n2.pdf: 158069 bytes, checksum: 7e6a26f22fdd9ff7f42fe85b116057b3 (MD5)Made available in DSpace on 2012-10-22T12:59:08Z (GMT). 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dc.title.pt_BR.fl_str_mv Etiology of Childhood Community Acquired Pneumonia and Its Implications for Vaccination
dc.title.alternative.pt_BR.fl_str_mv Brazilian Journal of Infectious Diseases
title Etiology of Childhood Community Acquired Pneumonia and Its Implications for Vaccination
spellingShingle Etiology of Childhood Community Acquired Pneumonia and Its Implications for Vaccination
Carvalho, Cristiana Maria Costa Nascimento de
community-acquired pneumonia
children
etiology
vaccine
S. pneumoniae
respiratory syncytial virus
title_short Etiology of Childhood Community Acquired Pneumonia and Its Implications for Vaccination
title_full Etiology of Childhood Community Acquired Pneumonia and Its Implications for Vaccination
title_fullStr Etiology of Childhood Community Acquired Pneumonia and Its Implications for Vaccination
title_full_unstemmed Etiology of Childhood Community Acquired Pneumonia and Its Implications for Vaccination
title_sort Etiology of Childhood Community Acquired Pneumonia and Its Implications for Vaccination
author Carvalho, Cristiana Maria Costa Nascimento de
author_facet Carvalho, Cristiana Maria Costa Nascimento de
author_role author
dc.contributor.author.fl_str_mv Carvalho, Cristiana Maria Costa Nascimento de
Carvalho, Cristiana Maria Costa Nascimento de
dc.subject.por.fl_str_mv community-acquired pneumonia
children
etiology
vaccine
S. pneumoniae
respiratory syncytial virus
topic community-acquired pneumonia
children
etiology
vaccine
S. pneumoniae
respiratory syncytial virus
description p. 87-97
publishDate 2001
dc.date.issued.fl_str_mv 2001
dc.date.accessioned.fl_str_mv 2012-10-22T12:59:08Z
dc.date.available.fl_str_mv 2012-10-22T12:59:08Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/7010
dc.identifier.issn.none.fl_str_mv 1413-8670
dc.identifier.number.pt_BR.fl_str_mv v. 5, n. 2
identifier_str_mv 1413-8670
v. 5, n. 2
url http://www.repositorio.ufba.br/ri/handle/ri/7010
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1590/S1413-86702001000200007
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
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reponame_str Repositório Institucional da UFBA
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