Ocular lesions in sickle cell disease patients from Bahia, Brazil
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/5751 |
Resumo: | p. 259-263. |
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Cury, DayseBoa Sorte, Ney Cristian AmaralLyra, Isa MenezesZanette, Angela Maria DiasCastro-Lima, HumbertoGalvão-Castro, BernardoGonçalves, Marilda SouzaCury, DayseBoa Sorte, Ney Cristian AmaralLyra, Isa MenezesZanette, Angela Maria DiasCastro-Lima, HumbertoGalvão-Castro, BernardoGonçalves, Marilda Souza2012-04-26T11:54:10Z2012-04-26T11:54:10Z20100034-7280http://www.repositorio.ufba.br/ri/handle/ri/5751v. 69, n. 4p. 259-263.OBJECTIVE: The present study aims to describe ocular alterations in sickle cell disease patients in Bahia, a Northeast state, with the highest prevalence of the disease in Brazil. METHODS: We carried out a cross-sectional study in a group of 146 (292 eyes) sickle cell disease patients (90 HBSS and 56 HBSC). Ophthalmologic examination including indirect binocular ophthalmoscopy was performed. Examination was completed by fluorescein angiography to detect retinal lesions. RESULTS: The most frequent ocular lesions identified were "vascular tortuosity" and "black sunburst". Proliferative retinopathy was found in 22 (12.2%) eyes of HBSS patients and 25 (22.3%) eyes of HBSC patients (OR=2.06; CI95%: 1.5-4.06, p=0.022); Its frequency was higher among HBSS patients aged 20-39 years, while in HBSC patients, it peaked after 40 years (35.7% and 42.8%) and dropped sharply afterwards. CONCLUSION: Proliferative retinopathy was described as early as 10 years of age in both patients groups. Proliferative sickle retinopathy can result in blindness and the knowledge of the most prevalent ocular alterations and age risk will be important to establish a protocol of ophthalmologic follow-up, in order to prevent a severe visual loss and increase patient's life quality.Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2012-04-26T11:54:10Z No. of bitstreams: 1 __www.scielo.br_pdf_rbof_v69n4_v69n4a10.pdf: 105437 bytes, checksum: 6a657a9cb454ef886cbf877c1f5d079c (MD5)Made available in DSpace on 2012-04-26T11:54:10Z (GMT). No. of bitstreams: 1 __www.scielo.br_pdf_rbof_v69n4_v69n4a10.pdf: 105437 bytes, checksum: 6a657a9cb454ef886cbf877c1f5d079c (MD5) Previous issue date: 2010Rio de Janeirohttp://dx.doi.org/10.1590/S0034-72802010000400010reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAAnemiasickle cellHemoglobin SC diseaseEye injuriesRetinal diseasesOcular lesions in sickle cell disease patients from Bahia, BrazilRevista Brasileira de Oftalmologiainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleenginfo:eu-repo/semantics/openAccessORIGINAL__www.scielo.br_pdf_rbof_v69n4_v69n4a10.pdf__www.scielo.br_pdf_rbof_v69n4_v69n4a10.pdfapplication/pdf105437https://repositorio.ufba.br/bitstream/ri/5751/1/__www.scielo.br_pdf_rbof_v69n4_v69n4a10.pdf6a657a9cb454ef886cbf877c1f5d079cMD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/5751/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXT__www.scielo.br_pdf_rbof_v69n4_v69n4a10.pdf.txt__www.scielo.br_pdf_rbof_v69n4_v69n4a10.pdf.txtExtracted texttext/plain22080https://repositorio.ufba.br/bitstream/ri/5751/3/__www.scielo.br_pdf_rbof_v69n4_v69n4a10.pdf.txt18d3d5c67c61c37f9ebbd27ba0c35bc0MD53ri/57512022-07-05 14:03:21.298oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:21Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
dc.title.pt_BR.fl_str_mv |
Ocular lesions in sickle cell disease patients from Bahia, Brazil |
dc.title.alternative.pt_BR.fl_str_mv |
Revista Brasileira de Oftalmologia |
title |
Ocular lesions in sickle cell disease patients from Bahia, Brazil |
spellingShingle |
Ocular lesions in sickle cell disease patients from Bahia, Brazil Cury, Dayse Anemia sickle cell Hemoglobin SC disease Eye injuries Retinal diseases |
title_short |
Ocular lesions in sickle cell disease patients from Bahia, Brazil |
title_full |
Ocular lesions in sickle cell disease patients from Bahia, Brazil |
title_fullStr |
Ocular lesions in sickle cell disease patients from Bahia, Brazil |
title_full_unstemmed |
Ocular lesions in sickle cell disease patients from Bahia, Brazil |
title_sort |
Ocular lesions in sickle cell disease patients from Bahia, Brazil |
author |
Cury, Dayse |
author_facet |
Cury, Dayse Boa Sorte, Ney Cristian Amaral Lyra, Isa Menezes Zanette, Angela Maria Dias Castro-Lima, Humberto Galvão-Castro, Bernardo Gonçalves, Marilda Souza |
author_role |
author |
author2 |
Boa Sorte, Ney Cristian Amaral Lyra, Isa Menezes Zanette, Angela Maria Dias Castro-Lima, Humberto Galvão-Castro, Bernardo Gonçalves, Marilda Souza |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Cury, Dayse Boa Sorte, Ney Cristian Amaral Lyra, Isa Menezes Zanette, Angela Maria Dias Castro-Lima, Humberto Galvão-Castro, Bernardo Gonçalves, Marilda Souza Cury, Dayse Boa Sorte, Ney Cristian Amaral Lyra, Isa Menezes Zanette, Angela Maria Dias Castro-Lima, Humberto Galvão-Castro, Bernardo Gonçalves, Marilda Souza |
dc.subject.por.fl_str_mv |
Anemia sickle cell Hemoglobin SC disease Eye injuries Retinal diseases |
topic |
Anemia sickle cell Hemoglobin SC disease Eye injuries Retinal diseases |
description |
p. 259-263. |
publishDate |
2010 |
dc.date.issued.fl_str_mv |
2010 |
dc.date.accessioned.fl_str_mv |
2012-04-26T11:54:10Z |
dc.date.available.fl_str_mv |
2012-04-26T11:54:10Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://www.repositorio.ufba.br/ri/handle/ri/5751 |
dc.identifier.issn.none.fl_str_mv |
0034-7280 |
dc.identifier.number.pt_BR.fl_str_mv |
v. 69, n. 4 |
identifier_str_mv |
0034-7280 v. 69, n. 4 |
url |
http://www.repositorio.ufba.br/ri/handle/ri/5751 |
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eng |
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eng |
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http://dx.doi.org/10.1590/S0034-72802010000400010 |
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