Ocular lesions in sickle cell disease patients from Bahia, Brazil

Detalhes bibliográficos
Autor(a) principal: Cury, Dayse
Data de Publicação: 2010
Outros Autores: Boa Sorte, Ney Cristian Amaral, Lyra, Isa Menezes, Zanette, Angela Maria Dias, Castro-Lima, Humberto, Galvão-Castro, Bernardo, Gonçalves, Marilda Souza
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/5751
Resumo: p. 259-263.
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spelling Cury, DayseBoa Sorte, Ney Cristian AmaralLyra, Isa MenezesZanette, Angela Maria DiasCastro-Lima, HumbertoGalvão-Castro, BernardoGonçalves, Marilda SouzaCury, DayseBoa Sorte, Ney Cristian AmaralLyra, Isa MenezesZanette, Angela Maria DiasCastro-Lima, HumbertoGalvão-Castro, BernardoGonçalves, Marilda Souza2012-04-26T11:54:10Z2012-04-26T11:54:10Z20100034-7280http://www.repositorio.ufba.br/ri/handle/ri/5751v. 69, n. 4p. 259-263.OBJECTIVE: The present study aims to describe ocular alterations in sickle cell disease patients in Bahia, a Northeast state, with the highest prevalence of the disease in Brazil. METHODS: We carried out a cross-sectional study in a group of 146 (292 eyes) sickle cell disease patients (90 HBSS and 56 HBSC). Ophthalmologic examination including indirect binocular ophthalmoscopy was performed. Examination was completed by fluorescein angiography to detect retinal lesions. RESULTS: The most frequent ocular lesions identified were "vascular tortuosity" and "black sunburst". Proliferative retinopathy was found in 22 (12.2%) eyes of HBSS patients and 25 (22.3%) eyes of HBSC patients (OR=2.06; CI95%: 1.5-4.06, p=0.022); Its frequency was higher among HBSS patients aged 20-39 years, while in HBSC patients, it peaked after 40 years (35.7% and 42.8%) and dropped sharply afterwards. CONCLUSION: Proliferative retinopathy was described as early as 10 years of age in both patients groups. Proliferative sickle retinopathy can result in blindness and the knowledge of the most prevalent ocular alterations and age risk will be important to establish a protocol of ophthalmologic follow-up, in order to prevent a severe visual loss and increase patient's life quality.Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2012-04-26T11:54:10Z No. of bitstreams: 1 __www.scielo.br_pdf_rbof_v69n4_v69n4a10.pdf: 105437 bytes, checksum: 6a657a9cb454ef886cbf877c1f5d079c (MD5)Made available in DSpace on 2012-04-26T11:54:10Z (GMT). No. of bitstreams: 1 __www.scielo.br_pdf_rbof_v69n4_v69n4a10.pdf: 105437 bytes, checksum: 6a657a9cb454ef886cbf877c1f5d079c (MD5) Previous issue date: 2010Rio de Janeirohttp://dx.doi.org/10.1590/S0034-72802010000400010reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAAnemiasickle cellHemoglobin SC diseaseEye injuriesRetinal diseasesOcular lesions in sickle cell disease patients from Bahia, BrazilRevista Brasileira de Oftalmologiainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleenginfo:eu-repo/semantics/openAccessORIGINAL__www.scielo.br_pdf_rbof_v69n4_v69n4a10.pdf__www.scielo.br_pdf_rbof_v69n4_v69n4a10.pdfapplication/pdf105437https://repositorio.ufba.br/bitstream/ri/5751/1/__www.scielo.br_pdf_rbof_v69n4_v69n4a10.pdf6a657a9cb454ef886cbf877c1f5d079cMD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/5751/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXT__www.scielo.br_pdf_rbof_v69n4_v69n4a10.pdf.txt__www.scielo.br_pdf_rbof_v69n4_v69n4a10.pdf.txtExtracted texttext/plain22080https://repositorio.ufba.br/bitstream/ri/5751/3/__www.scielo.br_pdf_rbof_v69n4_v69n4a10.pdf.txt18d3d5c67c61c37f9ebbd27ba0c35bc0MD53ri/57512022-07-05 14:03:21.298oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:21Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Ocular lesions in sickle cell disease patients from Bahia, Brazil
dc.title.alternative.pt_BR.fl_str_mv Revista Brasileira de Oftalmologia
title Ocular lesions in sickle cell disease patients from Bahia, Brazil
spellingShingle Ocular lesions in sickle cell disease patients from Bahia, Brazil
Cury, Dayse
Anemia
sickle cell
Hemoglobin SC disease
Eye injuries
Retinal diseases
title_short Ocular lesions in sickle cell disease patients from Bahia, Brazil
title_full Ocular lesions in sickle cell disease patients from Bahia, Brazil
title_fullStr Ocular lesions in sickle cell disease patients from Bahia, Brazil
title_full_unstemmed Ocular lesions in sickle cell disease patients from Bahia, Brazil
title_sort Ocular lesions in sickle cell disease patients from Bahia, Brazil
author Cury, Dayse
author_facet Cury, Dayse
Boa Sorte, Ney Cristian Amaral
Lyra, Isa Menezes
Zanette, Angela Maria Dias
Castro-Lima, Humberto
Galvão-Castro, Bernardo
Gonçalves, Marilda Souza
author_role author
author2 Boa Sorte, Ney Cristian Amaral
Lyra, Isa Menezes
Zanette, Angela Maria Dias
Castro-Lima, Humberto
Galvão-Castro, Bernardo
Gonçalves, Marilda Souza
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Cury, Dayse
Boa Sorte, Ney Cristian Amaral
Lyra, Isa Menezes
Zanette, Angela Maria Dias
Castro-Lima, Humberto
Galvão-Castro, Bernardo
Gonçalves, Marilda Souza
Cury, Dayse
Boa Sorte, Ney Cristian Amaral
Lyra, Isa Menezes
Zanette, Angela Maria Dias
Castro-Lima, Humberto
Galvão-Castro, Bernardo
Gonçalves, Marilda Souza
dc.subject.por.fl_str_mv Anemia
sickle cell
Hemoglobin SC disease
Eye injuries
Retinal diseases
topic Anemia
sickle cell
Hemoglobin SC disease
Eye injuries
Retinal diseases
description p. 259-263.
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2012-04-26T11:54:10Z
dc.date.available.fl_str_mv 2012-04-26T11:54:10Z
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dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/5751
dc.identifier.issn.none.fl_str_mv 0034-7280
dc.identifier.number.pt_BR.fl_str_mv v. 69, n. 4
identifier_str_mv 0034-7280
v. 69, n. 4
url http://www.repositorio.ufba.br/ri/handle/ri/5751
dc.language.iso.fl_str_mv eng
language eng
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