Characteristics of co-infections by HCV and HBV among Brazilian patients infected by HIV-1 and/or HTLV-1

Detalhes bibliográficos
Autor(a) principal: Moreira, Marcia
Data de Publicação: 2013
Outros Autores: Ramos, André, Martins Netto, Eduardo, Brites, Carlos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/15553
Resumo: Texto completo: acesso restrito. p. 661–666
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spelling Moreira, MarciaRamos, AndréMartins Netto, EduardoBrites, CarlosMoreira, MarciaRamos, AndréMartins Netto, EduardoBrites, Carlos2014-08-11T19:09:04Z20131413-8670http://repositorio.ufba.br/ri/handle/ri/15553v. 17, n. 6Texto completo: acesso restrito. p. 661–666Background: The human retroviruses HIV-1 and HTLV-1 share the routes of infection with hepatitis viruses B and C. Co-infection by these agents are a common event, but we have scarce knowledge on co-infection by two or more of these agents. Objective: To evaluate the characteristics and risk factors for co-infections by HBV and HCV in patients infected by HIV-1 or/and HTLV-1, in Salvador, Brazil. Methods: In a case–control study we evaluated patients followed in the AIDS and HTLV clinics of Federal University of Bahia Hospital. Clinical and epidemiological characteristics were reviewed, and patients were tested for the presence of serological markers of HBV and HCV infections. HCV-infected patients were tested by PCR to evaluate the presence of viremia. Results: A total of 200 HIV-1, 213 HTLV-1-infected, and 38 HIV-HTLV-co-infected individuals were included. HIV-infected patients were more likely to have had more sexual partners in the lifetime than other patients’ groups. HIV-HTLV-co-infected subjects were predominantly male. Patients infected by HTLV or co-infected had a significantly higher frequency of previous syphilis or gonorrhea, while HIV infection was mainly associated with HPV infection. Co-infection was significantly associated to intravenous drug use (IVDU). HBV and/or HCV markers were more frequently found among co-infected patients. HBV markers were more frequently detected among HIV-infected patients, while HCV was clearly associated with IVDU across all groups. AgHBs was strongly associated with co-infection by HIV-HTLV (OR = 22.03, 95% CI: 2.69–469.7), as well as confirmed HCV infection (p = 0.001). Concomitant HCV and HBV infection was also associated with retroviral co-infection. Patients infected by HTLV-1 had a lower chance of detectable HCV viremia (OR = 0.04, 95% CI: 0.002–0.85). Conclusions: Infection by HCV and/or HBV is frequent among patients presenting retroviral infection, but risk factors and prevalence for each infection are distinct for each agent. Retroviral co-infection increases the risk of a positive AgHBs, but HTLV-1 infection seems to increase the likelihood of HCV spontaneous clearance.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-04-10T12:36:19Z No. of bitstreams: 1 1-s2.0-S1413867013001979-main.pdf: 498614 bytes, checksum: 3ff644e41bdbb506a043fcd2bd56e238 (MD5)Approved for entry into archive by Patricia Barroso (pbarroso@ufba.br) on 2014-08-11T19:09:04Z (GMT) No. of bitstreams: 1 1-s2.0-S1413867013001979-main.pdf: 498614 bytes, checksum: 3ff644e41bdbb506a043fcd2bd56e238 (MD5)Made available in DSpace on 2014-08-11T19:09:04Z (GMT). No. of bitstreams: 1 1-s2.0-S1413867013001979-main.pdf: 498614 bytes, checksum: 3ff644e41bdbb506a043fcd2bd56e238 (MD5) Previous issue date: 2013http://dx.doi.org/10.1016/j.bjid.2013.04.009reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAHIV-1HTLV-1CoinfectionHCVHBVBrazilCharacteristics of co-infections by HCV and HBV among Brazilian patients infected by HIV-1 and/or HTLV-1Brazilian Journal of Infectious Diseasesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINAL1-s2.0-S1413867013001979-main.pdf1-s2.0-S1413867013001979-main.pdfapplication/pdf498614https://repositorio.ufba.br/bitstream/ri/15553/1/1-s2.0-S1413867013001979-main.pdf3ff644e41bdbb506a043fcd2bd56e238MD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/15553/2/license.txt0d4b811ef71182510d2015daa7c8a900MD52TEXT1-s2.0-S1413867013001979-main.pdf.txt1-s2.0-S1413867013001979-main.pdf.txtExtracted texttext/plain28714https://repositorio.ufba.br/bitstream/ri/15553/3/1-s2.0-S1413867013001979-main.pdf.txtf5b255b1c2f1a28cccc09074e61c2fcfMD53ri/155532022-07-05 14:03:13.718oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:13Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Characteristics of co-infections by HCV and HBV among Brazilian patients infected by HIV-1 and/or HTLV-1
dc.title.alternative.pt_BR.fl_str_mv Brazilian Journal of Infectious Diseases
title Characteristics of co-infections by HCV and HBV among Brazilian patients infected by HIV-1 and/or HTLV-1
spellingShingle Characteristics of co-infections by HCV and HBV among Brazilian patients infected by HIV-1 and/or HTLV-1
Moreira, Marcia
HIV-1
HTLV-1
Coinfection
HCV
HBV
Brazil
title_short Characteristics of co-infections by HCV and HBV among Brazilian patients infected by HIV-1 and/or HTLV-1
title_full Characteristics of co-infections by HCV and HBV among Brazilian patients infected by HIV-1 and/or HTLV-1
title_fullStr Characteristics of co-infections by HCV and HBV among Brazilian patients infected by HIV-1 and/or HTLV-1
title_full_unstemmed Characteristics of co-infections by HCV and HBV among Brazilian patients infected by HIV-1 and/or HTLV-1
title_sort Characteristics of co-infections by HCV and HBV among Brazilian patients infected by HIV-1 and/or HTLV-1
author Moreira, Marcia
author_facet Moreira, Marcia
Ramos, André
Martins Netto, Eduardo
Brites, Carlos
author_role author
author2 Ramos, André
Martins Netto, Eduardo
Brites, Carlos
author2_role author
author
author
dc.contributor.author.fl_str_mv Moreira, Marcia
Ramos, André
Martins Netto, Eduardo
Brites, Carlos
Moreira, Marcia
Ramos, André
Martins Netto, Eduardo
Brites, Carlos
dc.subject.por.fl_str_mv HIV-1
HTLV-1
Coinfection
HCV
HBV
Brazil
topic HIV-1
HTLV-1
Coinfection
HCV
HBV
Brazil
description Texto completo: acesso restrito. p. 661–666
publishDate 2013
dc.date.issued.fl_str_mv 2013
dc.date.accessioned.fl_str_mv 2014-08-11T19:09:04Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/15553
dc.identifier.issn.none.fl_str_mv 1413-8670
dc.identifier.number.pt_BR.fl_str_mv v. 17, n. 6
identifier_str_mv 1413-8670
v. 17, n. 6
url http://repositorio.ufba.br/ri/handle/ri/15553
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1016/j.bjid.2013.04.009
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
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reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
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