Clear cell odontogenic carcinoma: case report with immunohistochemical findings adding support to the challenging diagnosis

Detalhes bibliográficos
Autor(a) principal: Xavier, Flávia Caló de Aquino
Data de Publicação: 2008
Outros Autores: Rodini, Camila Oliveira, Ramalho, Luciana Maria Pedreira, Sarmento, Viviane Almeida, Nunes, Fabio Daumas
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/6071
Resumo: Acesso restrito: Texto completo. p. 403-410
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spelling Xavier, Flávia Caló de AquinoRodini, Camila OliveiraRamalho, Luciana Maria PedreiraSarmento, Viviane AlmeidaNunes, Fabio DaumasXavier, Flávia Caló de AquinoRodini, Camila OliveiraRamalho, Luciana Maria PedreiraSarmento, Viviane AlmeidaNunes, Fabio Daumas2012-06-04T19:41:16Z20081079-2104http://www.repositorio.ufba.br/ri/handle/ri/6071v. 106, n. 3Acesso restrito: Texto completo. p. 403-410Clear cell odontogenic carcinoma (CCOC) is a rare odontogenic tumor associated with aggressive clinical behavior, metastasis, and low survival. We report a case of CCOC affecting the mandible of a 39-year-old man. The tumor presented a biphasic pattern composed of clear cell nests intermingled with eosinophilic cells and separated by collagenous stroma. Immunoreactivity to cytokeratin (CK), specifically AE1/AE3 and CK 8, 14, 18, and 19 was found, as well as to epithelial membrane antigen (EMA). The tumor cells were negative for S100 protein, CK 13, vimentin, smooth muscle actin, laminin and type IV collagen. Low labeling indices for the proliferation markers Ki-67 and proliferating cell nuclear antigen and to p53 protein might predict a favorable prognosis for the lesion. A surgical resection was performed, followed by adjuvant radiotherapy. A 2-year follow-up has shown no signs of recurrence. The significance of histochemical and immunohistochemical resources in the correct diagnosis of CCOC is analyzed. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;106:403-10)Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2012-06-04T19:41:16Z No. of bitstreams: 1 __ac.els-cdn.com_S107921...b304639c56e34d0a0fac964a42f13.pdf: 558329 bytes, checksum: 9c674c2aaaa8afd71ed70b116a3c93b3 (MD5)Made available in DSpace on 2012-06-04T19:41:16Z (GMT). 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dc.title.pt_BR.fl_str_mv Clear cell odontogenic carcinoma: case report with immunohistochemical findings adding support to the challenging diagnosis
dc.title.alternative.pt_BR.fl_str_mv Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology
title Clear cell odontogenic carcinoma: case report with immunohistochemical findings adding support to the challenging diagnosis
spellingShingle Clear cell odontogenic carcinoma: case report with immunohistochemical findings adding support to the challenging diagnosis
Xavier, Flávia Caló de Aquino
title_short Clear cell odontogenic carcinoma: case report with immunohistochemical findings adding support to the challenging diagnosis
title_full Clear cell odontogenic carcinoma: case report with immunohistochemical findings adding support to the challenging diagnosis
title_fullStr Clear cell odontogenic carcinoma: case report with immunohistochemical findings adding support to the challenging diagnosis
title_full_unstemmed Clear cell odontogenic carcinoma: case report with immunohistochemical findings adding support to the challenging diagnosis
title_sort Clear cell odontogenic carcinoma: case report with immunohistochemical findings adding support to the challenging diagnosis
author Xavier, Flávia Caló de Aquino
author_facet Xavier, Flávia Caló de Aquino
Rodini, Camila Oliveira
Ramalho, Luciana Maria Pedreira
Sarmento, Viviane Almeida
Nunes, Fabio Daumas
author_role author
author2 Rodini, Camila Oliveira
Ramalho, Luciana Maria Pedreira
Sarmento, Viviane Almeida
Nunes, Fabio Daumas
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Xavier, Flávia Caló de Aquino
Rodini, Camila Oliveira
Ramalho, Luciana Maria Pedreira
Sarmento, Viviane Almeida
Nunes, Fabio Daumas
Xavier, Flávia Caló de Aquino
Rodini, Camila Oliveira
Ramalho, Luciana Maria Pedreira
Sarmento, Viviane Almeida
Nunes, Fabio Daumas
description Acesso restrito: Texto completo. p. 403-410
publishDate 2008
dc.date.issued.fl_str_mv 2008
dc.date.accessioned.fl_str_mv 2012-06-04T19:41:16Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/6071
dc.identifier.issn.none.fl_str_mv 1079-2104
dc.identifier.number.pt_BR.fl_str_mv v. 106, n. 3
identifier_str_mv 1079-2104
v. 106, n. 3
url http://www.repositorio.ufba.br/ri/handle/ri/6071
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1016/j.tripleo.2008.03.010
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
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