Elevated manganeseandcognitiveperformanceinschool-agedchildren and theirmothers

Detalhes bibliográficos
Autor(a) principal: Menezes Filho, José Antônio
Data de Publicação: 2011
Outros Autores: Novaes, Cristianede O., Moreira, Josino C., Sarcinelli, Paula N., Mergler, Donna
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/5578
Resumo: Acesso restrito: Texto completo. p. 156-163
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spelling Menezes Filho, José AntônioNovaes, Cristianede O.Moreira, Josino C.Sarcinelli, Paula N.Mergler, DonnaMenezes Filho, José AntônioNovaes, Cristianede O.Moreira, Josino C.Sarcinelli, Paula N.Mergler, Donna2012-03-30T12:20:43Z20110013-9351http://www.repositorio.ufba.br/ri/handle/ri/5578v. 111, n. 1Acesso restrito: Texto completo. p. 156-163Background: Growing evidence suggests thatexcessmanganese(Mn)inchildrenisassociatedwithneuro behavioralimpairments.InBrazil,elevatedhairMnconcentrationswerereportedinchildrenlivingneara ferro-manganesealloyplant. Objectives: We investigatedthesechildren’sandcaregivers’cognitivefunctioninrelationtobio- indicators ofMnexposure. Methods: In thiscross-sectionalstudy,theWISC-IIIwasadministeredto83childrenagedbetween6and 12 years;theRavenProgressiveMatrixwasadministeredtotheprimarycaregivers(94%mothers),who likewiserespondedtoaquestionnaireonsociodemographicsandbirthhistory.Mninhair(MnH)and blood (MnB)andbloodlead(PbB)weremeasuredbygraphitefurnaceatomicabsorptionspectrometry (GFAAS). Results: Children’smeanMnBandMnHwere8.2 mg/L (2.7–23.4)and5.83 mg/g (0.1–86.68),respectively. Mean maternalMnHwas3.50 mg/g (0.10–77.45)andcorrelatedtochildren’sMnH(rho¼0.294, p¼0.010).Children’sMnHwasnegativelyrelatedtoFull-ScaleIntelligenceQuotient(IQ)andVerbalIQ; b coefficientsforMnHwere 5.78 (95%CI 10.71to 0.21) and 6.72( 11.81to 0.63),adjusted for maternaleducationandnutritionalstatus.MaternalMnHwasnegativelyassociatedwith performanceontheRaven’s(b¼ 2.69,95%CI 5.43 to0.05),adjustedforeducationyears,family incomeandage. Conclusions: These findingsconfirmthathighMnHinchildrenisassociatedwithpoorercognitive performance,especiallyintheverbaldomain.Primarycaregiver’sIQislikewiseassociatedtoMn exposure,suggestingthat,inthissituation,children’scognitionmaybeaffecteddirectlyandindirectly by Mnexposure.Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2012-03-30T12:20:43Z No. of bitstreams: 1 __ac.els-cdn.com_S001393...7006e68d9730a28260ad92b3a9982.pdf: 236784 bytes, checksum: b6cc1f64f1509dd4bf661be5ec55cc3c (MD5)Made available in DSpace on 2012-03-30T12:20:43Z (GMT). No. of bitstreams: 1 __ac.els-cdn.com_S001393...7006e68d9730a28260ad92b3a9982.pdf: 236784 bytes, checksum: b6cc1f64f1509dd4bf661be5ec55cc3c (MD5) Previous issue date: 2011DOI: 10.1016/j.envres.2010.09.006reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAManganeseIntelligenceChildrenNeurobehavioralAlloy plantElevated manganeseandcognitiveperformanceinschool-agedchildren and theirmothersEnvironmental Researchinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01enginfo:eu-repo/semantics/openAccessORIGINAL__ac.els-cdn.com_S001393...7006e68d9730a28260ad92b3a9982.pdf__ac.els-cdn.com_S001393...7006e68d9730a28260ad92b3a9982.pdfapplication/pdf236784https://repositorio.ufba.br/bitstream/ri/5578/1/__ac.els-cdn.com_S001393...7006e68d9730a28260ad92b3a9982.pdfb6cc1f64f1509dd4bf661be5ec55cc3cMD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/5578/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXT__ac.els-cdn.com_S001393...7006e68d9730a28260ad92b3a9982.pdf.txt__ac.els-cdn.com_S001393...7006e68d9730a28260ad92b3a9982.pdf.txtExtracted texttext/plain47181https://repositorio.ufba.br/bitstream/ri/5578/3/__ac.els-cdn.com_S001393...7006e68d9730a28260ad92b3a9982.pdf.txt8b5810e681f32efe2c3c79816bae914dMD53ri/55782022-07-05 14:03:13.609oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:13Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Elevated manganeseandcognitiveperformanceinschool-agedchildren and theirmothers
dc.title.alternative.pt_BR.fl_str_mv Environmental Research
title Elevated manganeseandcognitiveperformanceinschool-agedchildren and theirmothers
spellingShingle Elevated manganeseandcognitiveperformanceinschool-agedchildren and theirmothers
Menezes Filho, José Antônio
Manganese
Intelligence
Children
Neurobehavioral
Alloy plant
title_short Elevated manganeseandcognitiveperformanceinschool-agedchildren and theirmothers
title_full Elevated manganeseandcognitiveperformanceinschool-agedchildren and theirmothers
title_fullStr Elevated manganeseandcognitiveperformanceinschool-agedchildren and theirmothers
title_full_unstemmed Elevated manganeseandcognitiveperformanceinschool-agedchildren and theirmothers
title_sort Elevated manganeseandcognitiveperformanceinschool-agedchildren and theirmothers
author Menezes Filho, José Antônio
author_facet Menezes Filho, José Antônio
Novaes, Cristianede O.
Moreira, Josino C.
Sarcinelli, Paula N.
Mergler, Donna
author_role author
author2 Novaes, Cristianede O.
Moreira, Josino C.
Sarcinelli, Paula N.
Mergler, Donna
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Menezes Filho, José Antônio
Novaes, Cristianede O.
Moreira, Josino C.
Sarcinelli, Paula N.
Mergler, Donna
Menezes Filho, José Antônio
Novaes, Cristianede O.
Moreira, Josino C.
Sarcinelli, Paula N.
Mergler, Donna
dc.subject.por.fl_str_mv Manganese
Intelligence
Children
Neurobehavioral
Alloy plant
topic Manganese
Intelligence
Children
Neurobehavioral
Alloy plant
description Acesso restrito: Texto completo. p. 156-163
publishDate 2011
dc.date.issued.fl_str_mv 2011
dc.date.accessioned.fl_str_mv 2012-03-30T12:20:43Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/5578
dc.identifier.issn.none.fl_str_mv 0013-9351
dc.identifier.number.pt_BR.fl_str_mv v. 111, n. 1
identifier_str_mv 0013-9351
v. 111, n. 1
url http://www.repositorio.ufba.br/ri/handle/ri/5578
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv DOI: 10.1016/j.envres.2010.09.006
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
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