The fragility of protein-protein interaction networks

Detalhes bibliográficos
Autor(a) principal: Andrade, Roberto Fernandes Silva
Data de Publicação: 2011
Outros Autores: Schneider, C. M., Shinbrot, T., Herrmann, H. J.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/16556
Resumo: Texto completo: acesso restrito. p. 1-5
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spelling Andrade, Roberto Fernandes SilvaSchneider, C. M.Shinbrot, T.Herrmann, H. J.Andrade, Roberto Fernandes SilvaSchneider, C. M.Shinbrot, T.Herrmann, H. J.2014-11-11T18:00:49Z20110295-5075http://repositorio.ufba.br/ri/handle/ri/16556v. 95, n. 1Texto completo: acesso restrito. p. 1-5The capacity to resist perturbations from the environment is crucial to the survival of all organisms. We quantitatively analyze the susceptibility of protein interaction networks of numerous organisms to random and targeted failures. We find for all organisms studied that random rewiring improves protein network robustness, so that actual networks are more fragile than rewired surrogates. This unexpected fragility contrasts with the behavior of networks such as the Internet, whose robustness decreases with random rewiring. We trace this surprising effect to the modular structure of protein networks.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-04-15T13:36:52Z No. of bitstreams: 1 R. F. S. Andrade.pdf: 1575474 bytes, checksum: d71f8b6f2fcfc31227707a6493094a8d (MD5)Approved for entry into archive by Alda Lima da Silva (sivalda@ufba.br) on 2014-11-11T18:00:49Z (GMT) No. of bitstreams: 1 R. F. S. Andrade.pdf: 1575474 bytes, checksum: d71f8b6f2fcfc31227707a6493094a8d (MD5)Made available in DSpace on 2014-11-11T18:00:49Z (GMT). No. of bitstreams: 1 R. F. S. Andrade.pdf: 1575474 bytes, checksum: d71f8b6f2fcfc31227707a6493094a8d (MD5) Previous issue date: 2011http://dx.doi.org/ doi:10.1209/0295-5075/95/16001reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAThe fragility of protein-protein interaction networksEPLinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengLICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/16556/2/license.txt0d4b811ef71182510d2015daa7c8a900MD52ORIGINALR. F. S. Andrade.pdfR. F. S. Andrade.pdfapplication/pdf1575474https://repositorio.ufba.br/bitstream/ri/16556/1/R.%20F.%20S.%20Andrade.pdfd71f8b6f2fcfc31227707a6493094a8dMD51TEXTR. F. S. Andrade.pdf.txtR. F. S. Andrade.pdf.txtExtracted texttext/plain23155https://repositorio.ufba.br/bitstream/ri/16556/3/R.%20F.%20S.%20Andrade.pdf.txtf922a4eccd2577ad479e6e394742ba07MD53ri/165562022-07-05 14:02:48.709oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:02:48Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv The fragility of protein-protein interaction networks
dc.title.alternative.pt_BR.fl_str_mv EPL
title The fragility of protein-protein interaction networks
spellingShingle The fragility of protein-protein interaction networks
Andrade, Roberto Fernandes Silva
title_short The fragility of protein-protein interaction networks
title_full The fragility of protein-protein interaction networks
title_fullStr The fragility of protein-protein interaction networks
title_full_unstemmed The fragility of protein-protein interaction networks
title_sort The fragility of protein-protein interaction networks
author Andrade, Roberto Fernandes Silva
author_facet Andrade, Roberto Fernandes Silva
Schneider, C. M.
Shinbrot, T.
Herrmann, H. J.
author_role author
author2 Schneider, C. M.
Shinbrot, T.
Herrmann, H. J.
author2_role author
author
author
dc.contributor.author.fl_str_mv Andrade, Roberto Fernandes Silva
Schneider, C. M.
Shinbrot, T.
Herrmann, H. J.
Andrade, Roberto Fernandes Silva
Schneider, C. M.
Shinbrot, T.
Herrmann, H. J.
description Texto completo: acesso restrito. p. 1-5
publishDate 2011
dc.date.issued.fl_str_mv 2011
dc.date.accessioned.fl_str_mv 2014-11-11T18:00:49Z
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dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/16556
dc.identifier.issn.none.fl_str_mv 0295-5075
dc.identifier.number.pt_BR.fl_str_mv v. 95, n. 1
identifier_str_mv 0295-5075
v. 95, n. 1
url http://repositorio.ufba.br/ri/handle/ri/16556
dc.language.iso.fl_str_mv eng
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