Dihedral-angle Gaussian distribution driving protein folding

Detalhes bibliográficos
Autor(a) principal: Figueiredo, P. H.
Data de Publicação: 2008
Outros Autores: Moret, M. A., Nogueira Júnior, E., Coutinho, Sérgio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/6347
Resumo: Acesso restrito: Texto completo. p. 2019-2024.
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spelling Figueiredo, P. H.Moret, M. A.Nogueira Júnior, E.Coutinho, SérgioFigueiredo, P. H.Moret, M. A.Nogueira Júnior, E.Coutinho, Sérgio2012-07-05T18:56:15Z20080378-4371http://www.repositorio.ufba.br/ri/handle/ri/6347v. 387, n. 8-9Acesso restrito: Texto completo. p. 2019-2024.The proposal of this paper is to provide a simple angular random-walk model to build up polypeptide structures, which encompass properties of dihedral angles of folded proteins. From this model, structures will be built with lengths ranging from 125 up to 400 amino acids for the different fractions of secondary structure motifs, in which dihedral angles were randomly chosen according to narrow Gaussian probability distributions. In order to measure the fractal dimension of proteins three different cases were analyzed. The first contained -helix structures only, the second -strands structures and the third a mix of -helices and -sheets. The behavior of proteins with -helix motifs are more compact than in other situations. The findings herein indicate that this model describes some structural properties of a protein and suggest that randomness is an essential ingredient but proteins are driven by narrow angular Gaussian probability distributions and not by random-walk processes.Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2012-07-05T18:56:15Z No. of bitstreams: 1 CONFIG~1....0-S0378437107012599-main.pdf: 156628 bytes, checksum: f49db9982f0445c68341a68798fbdb2b (MD5)Made available in DSpace on 2012-07-05T18:56:15Z (GMT). No. of bitstreams: 1 CONFIG~1....0-S0378437107012599-main.pdf: 156628 bytes, checksum: f49db9982f0445c68341a68798fbdb2b (MD5) Previous issue date: 2008http://dx.doi.org/10.1016/j.physa.2007.11.034reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAProtein structureAngular Gaussian-walkRadius of gyrationMass fractal exponentDihedral-angle Gaussian distribution driving protein foldingPhysica A-Statistical Mechanics And Its Applicationsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01enginfo:eu-repo/semantics/openAccessLICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/6347/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52ORIGINALCONFIG~1....0-S0378437107012599-main.pdfCONFIG~1....0-S0378437107012599-main.pdfapplication/pdf156628https://repositorio.ufba.br/bitstream/ri/6347/1/CONFIG~1....0-S0378437107012599-main.pdff49db9982f0445c68341a68798fbdb2bMD51TEXTCONFIG~1....0-S0378437107012599-main.pdf.txtCONFIG~1....0-S0378437107012599-main.pdf.txtExtracted texttext/plain20046https://repositorio.ufba.br/bitstream/ri/6347/3/CONFIG~1....0-S0378437107012599-main.pdf.txt6d564a3300986e8b821d5b960f876bd7MD53ri/63472022-07-05 14:03:08.068oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:08Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Dihedral-angle Gaussian distribution driving protein folding
dc.title.alternative.pt_BR.fl_str_mv Physica A-Statistical Mechanics And Its Applications
title Dihedral-angle Gaussian distribution driving protein folding
spellingShingle Dihedral-angle Gaussian distribution driving protein folding
Figueiredo, P. H.
Protein structure
Angular Gaussian-walk
Radius of gyration
Mass fractal exponent
title_short Dihedral-angle Gaussian distribution driving protein folding
title_full Dihedral-angle Gaussian distribution driving protein folding
title_fullStr Dihedral-angle Gaussian distribution driving protein folding
title_full_unstemmed Dihedral-angle Gaussian distribution driving protein folding
title_sort Dihedral-angle Gaussian distribution driving protein folding
author Figueiredo, P. H.
author_facet Figueiredo, P. H.
Moret, M. A.
Nogueira Júnior, E.
Coutinho, Sérgio
author_role author
author2 Moret, M. A.
Nogueira Júnior, E.
Coutinho, Sérgio
author2_role author
author
author
dc.contributor.author.fl_str_mv Figueiredo, P. H.
Moret, M. A.
Nogueira Júnior, E.
Coutinho, Sérgio
Figueiredo, P. H.
Moret, M. A.
Nogueira Júnior, E.
Coutinho, Sérgio
dc.subject.por.fl_str_mv Protein structure
Angular Gaussian-walk
Radius of gyration
Mass fractal exponent
topic Protein structure
Angular Gaussian-walk
Radius of gyration
Mass fractal exponent
description Acesso restrito: Texto completo. p. 2019-2024.
publishDate 2008
dc.date.issued.fl_str_mv 2008
dc.date.accessioned.fl_str_mv 2012-07-05T18:56:15Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/6347
dc.identifier.issn.none.fl_str_mv 0378-4371
dc.identifier.number.pt_BR.fl_str_mv v. 387, n. 8-9
identifier_str_mv 0378-4371
v. 387, n. 8-9
url http://www.repositorio.ufba.br/ri/handle/ri/6347
dc.language.iso.fl_str_mv eng
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dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1016/j.physa.2007.11.034
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