Effect of a 36-month pharmaceutical care program on pharmacotherapy adherence in elderly diabetic and hypertensive patients

Detalhes bibliográficos
Autor(a) principal: Pilger, Diogo
Data de Publicação: 2011
Outros Autores: Obreli Neto, Paulo Roque, Guidoni, Camilo Molino, Baldoni, André de Oliveira, Souza, Joice Mara Cruciol, Franco, Walderez Penteado Gaeti, Cuman, Roberto Kenji Nakamura
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/16289
Resumo: Texto completo: acesso restrito. p. 642-649
id UFBA-2_8e14bc84ffb3562874db592d467046bc
oai_identifier_str oai:repositorio.ufba.br:ri/16289
network_acronym_str UFBA-2
network_name_str Repositório Institucional da UFBA
repository_id_str 1932
spelling Pilger, DiogoObreli Neto, Paulo RoqueGuidoni, Camilo MolinoBaldoni, André de OliveiraSouza, Joice Mara CruciolFranco, Walderez Penteado GaetiCuman, Roberto Kenji NakamuraPilger, DiogoObreli Neto, Paulo RoqueGuidoni, Camilo MolinoBaldoni, André de OliveiraSouza, Joice Mara CruciolFranco, Walderez Penteado GaetiCuman, Roberto Kenji Nakamura2014-10-03T19:08:39Z20112210-7703http://repositorio.ufba.br/ri/handle/ri/16289v. 33, n. 4Texto completo: acesso restrito. p. 642-649Objective: The primary objective of this study was to evaluate the effect of a pharmaceutical care program on pharmacotherapy adherence in elderly diabetic and hypertensive patients. The clinical outcomes of this pharmacotherapy adherence approach were the secondary objective of the study. Setting: Public Primary Health Care Unit in a municipality in the Brazilian State of Sao Paulo. Method: A 36-month randomized, controlled, prospective clinical trial was carried out with 200 patients divided into two groups: control (n = 100) and intervention (n = 100). The control group received the usual care offered by the Primary Health Care Unit (medical and nurse consultancies). The patients randomized into the intervention group received pharmaceutical care intervention besides the usual care offered. Main outcome measure: Pharmacotherapy adherence (Morisky-Green test translated into Portuguese and computerized dispensed medication history) and clinical measurements (blood pressure, fasting glucose, A1C hemoglobin, triglycerides and total cholesterol) were evaluated at the baseline and up to 36 months. A P value <0.05 was considered statistically significant. Results: A total of 97 patients from the intervention group and 97 patients from the control group completed the study (n = 194). Significant improvements in the pharmacotherapy adherence were verified for the intervention group according to the Morisky-Green test (50.5% of adherent patients at baseline vs. 83.5% of adherent patients after 36 months; P < 0.001) and the computerized dispensed medication history (52.6% of adherent patients at baseline vs. 83.5% of adherent patients after 36 months; P < 0.001); no significant changes were verified in the control group. Significant improvements in the number of patients reaching adequate values for their blood pressure (26.8% at baseline vs. 86.6% after 36-months; P < 0.001), fasting glucose (29.9% at baseline vs. 70.1% after 36 months; P < 0.001), A1C hemoglobin (3.3% at baseline vs. 63.3% after 36 months; P < 0.001), triglycerides (47.4% at baseline vs. 74.2% after 36 months; P < 0.001) and total cholesterol (59.8% at baseline vs. 80.4% after 36 months; P = 0.002) were verified in the intervention group, but remained unchanged in the control group. Conclusion: These results indicated the effectiveness of pharmaceutical care in improving pharmacotherapy adherence, with positive effects in the clinical outcomes of the patients studied.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-04-15T13:34:40Z No. of bitstreams: 1 Diogo Pilger.pdf: 255242 bytes, checksum: 85f5789e3309b4e51cb77df7fc2d0672 (MD5)Approved for entry into archive by Alda Lima da Silva (sivalda@ufba.br) on 2014-10-03T19:08:39Z (GMT) No. of bitstreams: 1 Diogo Pilger.pdf: 255242 bytes, checksum: 85f5789e3309b4e51cb77df7fc2d0672 (MD5)Made available in DSpace on 2014-10-03T19:08:39Z (GMT). No. of bitstreams: 1 Diogo Pilger.pdf: 255242 bytes, checksum: 85f5789e3309b4e51cb77df7fc2d0672 (MD5) Previous issue date: 2011http://dx.doi.org/ 10.1007/s11096-011-9518-xreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBABrazilClinical trialDiabetesElderlyHypertensionMedication adherencePharmaceutical carePublic healthEffect of a 36-month pharmaceutical care program on pharmacotherapy adherence in elderly diabetic and hypertensive patientsInternational Journal of Clinical Pharmacyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengLICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/16289/2/license.txt0d4b811ef71182510d2015daa7c8a900MD52ORIGINALDiogo Pilger.pdfDiogo Pilger.pdfapplication/pdf255242https://repositorio.ufba.br/bitstream/ri/16289/1/Diogo%20Pilger.pdf85f5789e3309b4e51cb77df7fc2d0672MD51TEXTDiogo Pilger.pdf.txtDiogo Pilger.pdf.txtExtracted texttext/plain37083https://repositorio.ufba.br/bitstream/ri/16289/3/Diogo%20Pilger.pdf.txt9c1bac2cb3e17b9e79622216b866c975MD53ri/162892022-07-05 14:03:36.414oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:36Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Effect of a 36-month pharmaceutical care program on pharmacotherapy adherence in elderly diabetic and hypertensive patients
dc.title.alternative.pt_BR.fl_str_mv International Journal of Clinical Pharmacy
title Effect of a 36-month pharmaceutical care program on pharmacotherapy adherence in elderly diabetic and hypertensive patients
spellingShingle Effect of a 36-month pharmaceutical care program on pharmacotherapy adherence in elderly diabetic and hypertensive patients
Pilger, Diogo
Brazil
Clinical trial
Diabetes
Elderly
Hypertension
Medication adherence
Pharmaceutical care
Public health
title_short Effect of a 36-month pharmaceutical care program on pharmacotherapy adherence in elderly diabetic and hypertensive patients
title_full Effect of a 36-month pharmaceutical care program on pharmacotherapy adherence in elderly diabetic and hypertensive patients
title_fullStr Effect of a 36-month pharmaceutical care program on pharmacotherapy adherence in elderly diabetic and hypertensive patients
title_full_unstemmed Effect of a 36-month pharmaceutical care program on pharmacotherapy adherence in elderly diabetic and hypertensive patients
title_sort Effect of a 36-month pharmaceutical care program on pharmacotherapy adherence in elderly diabetic and hypertensive patients
author Pilger, Diogo
author_facet Pilger, Diogo
Obreli Neto, Paulo Roque
Guidoni, Camilo Molino
Baldoni, André de Oliveira
Souza, Joice Mara Cruciol
Franco, Walderez Penteado Gaeti
Cuman, Roberto Kenji Nakamura
author_role author
author2 Obreli Neto, Paulo Roque
Guidoni, Camilo Molino
Baldoni, André de Oliveira
Souza, Joice Mara Cruciol
Franco, Walderez Penteado Gaeti
Cuman, Roberto Kenji Nakamura
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Pilger, Diogo
Obreli Neto, Paulo Roque
Guidoni, Camilo Molino
Baldoni, André de Oliveira
Souza, Joice Mara Cruciol
Franco, Walderez Penteado Gaeti
Cuman, Roberto Kenji Nakamura
Pilger, Diogo
Obreli Neto, Paulo Roque
Guidoni, Camilo Molino
Baldoni, André de Oliveira
Souza, Joice Mara Cruciol
Franco, Walderez Penteado Gaeti
Cuman, Roberto Kenji Nakamura
dc.subject.por.fl_str_mv Brazil
Clinical trial
Diabetes
Elderly
Hypertension
Medication adherence
Pharmaceutical care
Public health
topic Brazil
Clinical trial
Diabetes
Elderly
Hypertension
Medication adherence
Pharmaceutical care
Public health
description Texto completo: acesso restrito. p. 642-649
publishDate 2011
dc.date.issued.fl_str_mv 2011
dc.date.accessioned.fl_str_mv 2014-10-03T19:08:39Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/16289
dc.identifier.issn.none.fl_str_mv 2210-7703
dc.identifier.number.pt_BR.fl_str_mv v. 33, n. 4
identifier_str_mv 2210-7703
v. 33, n. 4
url http://repositorio.ufba.br/ri/handle/ri/16289
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/ 10.1007/s11096-011-9518-x
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
bitstream.url.fl_str_mv https://repositorio.ufba.br/bitstream/ri/16289/2/license.txt
https://repositorio.ufba.br/bitstream/ri/16289/1/Diogo%20Pilger.pdf
https://repositorio.ufba.br/bitstream/ri/16289/3/Diogo%20Pilger.pdf.txt
bitstream.checksum.fl_str_mv 0d4b811ef71182510d2015daa7c8a900
85f5789e3309b4e51cb77df7fc2d0672
9c1bac2cb3e17b9e79622216b866c975
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)
repository.mail.fl_str_mv
_version_ 1808459473208999936

Registros relacionados