Triglycerides and alanine aminotransferase as screening markers for suspected fatty liver disease in obese children and adolescents

Detalhes bibliográficos
Autor(a) principal: Oliveira, Ana M.
Data de Publicação: 2009
Outros Autores: Oliveira, Nelson, Reis, Jussara C., Santos, Marcos V., Silva, Agnaluce M., Adan, Luís Fernando Fernandes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/13580
Resumo: Texto completo: acesso restrito. p.83-88
id UFBA-2_978fd0bf6e28bece949a5aa0e198b994
oai_identifier_str oai:repositorio.ufba.br:ri/13580
network_acronym_str UFBA-2
network_name_str Repositório Institucional da UFBA
repository_id_str 1932
spelling Oliveira, Ana M.Oliveira, NelsonReis, Jussara C.Santos, Marcos V.Silva, Agnaluce M.Adan, Luís Fernando FernandesOliveira, Ana M.Oliveira, NelsonReis, Jussara C.Santos, Marcos V.Silva, Agnaluce M.Adan, Luís Fernando Fernandes2013-11-06T21:13:12Z20090301-0163http://repositorio.ufba.br/ri/handle/ri/13580v. 71, n. 2Texto completo: acesso restrito. p.83-88Background/Aims: Metabolic syndrome (MS) and fatty liver disease (FLD) are on the rise. The association between these conditions in Brazilian youth is analyzed. Methods: 354 subjects (11.2 ± 3.1 years) were evaluated. FLD was suspected by ultrasound and computed tomography; weight and MS by BMI z-score and NCEP-ATPIII respectively. Results: Subjects were classified as: group 1 with suspected FLD and group 2 without and group 2 as ‘a’ (overweight/obese) and ‘b’ (normal weight). Comparing group 1 with 2a and 2b, differences in age (p = 0.016; p = 0.075), triglycerides (TG) (p = 0.021; p = 0.002), insulin (p = 0.652; p = 0.015) and homeostasis model assessment method of IR (HOMA-IR) (p = 0.737; p = 0.003) were found. Group 2a was divided into low/high alanine aminotransferase (ALT). A decrease in waist circumference and TG was found going from those with suspicion of FLD to obese with high and low ALT. Insulin and HOMA-IR in group 1 and high ALT were similar. Gender (OR 6.6; CI 1.9–22.5; p = 0.025), age (OR 1.3; CI 1.1–1.6; p = 0.006), TG (OR 10.4; CI 3.1–34.4; p = 0.005) were associated with suspected FLD. For every 10 U/l increase in ALT, there was a 4-fold greater chance of probable FLD (OR 4.01; CI 2.06–9.40; p < 0.001). Conclusion: Measurements of ALT and TG should be considered as screening for suspected FLD in overweight/obese youth.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-11-04T13:13:02Z No. of bitstreams: 1 Ana Oliveira.pdf: 143597 bytes, checksum: 7339c1249dad46a472d8ad4fc3df9af5 (MD5)Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2013-11-06T21:13:12Z (GMT) No. of bitstreams: 1 Ana Oliveira.pdf: 143597 bytes, checksum: 7339c1249dad46a472d8ad4fc3df9af5 (MD5)Made available in DSpace on 2013-11-06T21:13:12Z (GMT). No. of bitstreams: 1 Ana Oliveira.pdf: 143597 bytes, checksum: 7339c1249dad46a472d8ad4fc3df9af5 (MD5) Previous issue date: 2009http://dx.doi.org/10.1159/000183896reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAMetabolic syndromeObesitySuspected fatty liver diseaseScreening proceduresPediatricsTriglycerides and alanine aminotransferase as screening markers for suspected fatty liver disease in obese children and adolescentsHormone Researchinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALAna Oliveira.pdfAna Oliveira.pdfapplication/pdf143597https://repositorio.ufba.br/bitstream/ri/13580/1/Ana%20Oliveira.pdf7339c1249dad46a472d8ad4fc3df9af5MD51LICENSElicense.txtlicense.txttext/plain1383https://repositorio.ufba.br/bitstream/ri/13580/2/license.txt05eca2f01d0b3307819d0369dab18a34MD52TEXTAna Oliveira.pdf.txtAna Oliveira.pdf.txtExtracted texttext/plain30344https://repositorio.ufba.br/bitstream/ri/13580/3/Ana%20Oliveira.pdf.txt54a74f365b682eeefebcae21eab6732cMD53ri/135802022-07-05 14:02:49.231oai:repositorio.ufba.br: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ório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:02:49Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Triglycerides and alanine aminotransferase as screening markers for suspected fatty liver disease in obese children and adolescents
dc.title.alternative.pt_BR.fl_str_mv Hormone Research
title Triglycerides and alanine aminotransferase as screening markers for suspected fatty liver disease in obese children and adolescents
spellingShingle Triglycerides and alanine aminotransferase as screening markers for suspected fatty liver disease in obese children and adolescents
Oliveira, Ana M.
Metabolic syndrome
Obesity
Suspected fatty liver disease
Screening procedures
Pediatrics
title_short Triglycerides and alanine aminotransferase as screening markers for suspected fatty liver disease in obese children and adolescents
title_full Triglycerides and alanine aminotransferase as screening markers for suspected fatty liver disease in obese children and adolescents
title_fullStr Triglycerides and alanine aminotransferase as screening markers for suspected fatty liver disease in obese children and adolescents
title_full_unstemmed Triglycerides and alanine aminotransferase as screening markers for suspected fatty liver disease in obese children and adolescents
title_sort Triglycerides and alanine aminotransferase as screening markers for suspected fatty liver disease in obese children and adolescents
author Oliveira, Ana M.
author_facet Oliveira, Ana M.
Oliveira, Nelson
Reis, Jussara C.
Santos, Marcos V.
Silva, Agnaluce M.
Adan, Luís Fernando Fernandes
author_role author
author2 Oliveira, Nelson
Reis, Jussara C.
Santos, Marcos V.
Silva, Agnaluce M.
Adan, Luís Fernando Fernandes
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Oliveira, Ana M.
Oliveira, Nelson
Reis, Jussara C.
Santos, Marcos V.
Silva, Agnaluce M.
Adan, Luís Fernando Fernandes
Oliveira, Ana M.
Oliveira, Nelson
Reis, Jussara C.
Santos, Marcos V.
Silva, Agnaluce M.
Adan, Luís Fernando Fernandes
dc.subject.por.fl_str_mv Metabolic syndrome
Obesity
Suspected fatty liver disease
Screening procedures
Pediatrics
topic Metabolic syndrome
Obesity
Suspected fatty liver disease
Screening procedures
Pediatrics
description Texto completo: acesso restrito. p.83-88
publishDate 2009
dc.date.issued.fl_str_mv 2009
dc.date.accessioned.fl_str_mv 2013-11-06T21:13:12Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/13580
dc.identifier.issn.none.fl_str_mv 0301-0163
dc.identifier.number.pt_BR.fl_str_mv v. 71, n. 2
identifier_str_mv 0301-0163
v. 71, n. 2
url http://repositorio.ufba.br/ri/handle/ri/13580
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1159/000183896
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
bitstream.url.fl_str_mv https://repositorio.ufba.br/bitstream/ri/13580/1/Ana%20Oliveira.pdf
https://repositorio.ufba.br/bitstream/ri/13580/2/license.txt
https://repositorio.ufba.br/bitstream/ri/13580/3/Ana%20Oliveira.pdf.txt
bitstream.checksum.fl_str_mv 7339c1249dad46a472d8ad4fc3df9af5
05eca2f01d0b3307819d0369dab18a34
54a74f365b682eeefebcae21eab6732c
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)
repository.mail.fl_str_mv
_version_ 1808459463778107392

Registros relacionados