Flower cells in patients with infective dermatitis associated with HTLV-1

Detalhes bibliográficos
Autor(a) principal: Oliveira, Maria de Fátima Santos Paim de
Data de Publicação: 2010
Outros Autores: Vieira, Maria das Graças, Leite Primo, Janeusa Rita, Siqueira, Isadora C., Carvalho Filho, Edgar Marcelino de, Farré, Lourdes, Fatal, Priscila Lima, Bittencourt, Achilea Candida Lisboa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/5673
Resumo: Acesso restrito: Texto completo. p. 288-290
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spelling Oliveira, Maria de Fátima Santos Paim deVieira, Maria das GraçasLeite Primo, Janeusa RitaSiqueira, Isadora C.Carvalho Filho, Edgar Marcelino deFarré, LourdesFatal, Priscila LimaBittencourt, Achilea Candida LisboaOliveira, Maria de Fátima Santos Paim deVieira, Maria das GraçasLeite Primo, Janeusa RitaSiqueira, Isadora C.Carvalho Filho, Edgar Marcelino deFarré, LourdesFatal, Priscila LimaBittencourt, Achilea Candida Lisboa2012-04-19T18:25:12Z20101386-6532http://www.repositorio.ufba.br/ri/handle/ri/5673v. 48, n. 4Acesso restrito: Texto completo. p. 288-290Background Infective dermatitis associated with HTLV-1 (IDH) is a severe childhood form of eczema that may progress to adult T-cell leukemia/lymphoma (ATL). Objectivo In this study, the presence of clinical and laboratory parameters suggestive of ATL was evaluated in a cohort of 30 patients with IDH.Study design Over a period of 33 months, the patients were submitted to three-monthly clinical evaluations, routine laboratory exams, full blood count and blood smears, and to six-monthly blood sampling for HTLV-1 proviral load determination. HTLV-1 proviral load was quantified using real-time TaqMan PCR assay. Results Abnormal cells (Ably) were found in the peripheral blood smears of nine patients (30%), flower cells being detected in five of these cases (16.6%). The presence of Ably and flower cells was not associated with a higher proviral load in those patients. Conclusions This is the first report on the presence of flower cells in HTLV-1-infected children and adolescents. Furthermore, these cells have not previously been reported in IDH patients. The cases with flower cells probably represent precursory ATL cases, these patients being at a greater risk of developing ATL.Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2012-04-19T18:25:12Z No. of bitstreams: 1 __ac.els-cdn.com_S138665...e7a813108519b29f26a273dafbaf2.pdf: 102480 bytes, checksum: bd289554835311cc04a30827af536642 (MD5)Made available in DSpace on 2012-04-19T18:25:12Z (GMT). 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dc.title.pt_BR.fl_str_mv Flower cells in patients with infective dermatitis associated with HTLV-1
dc.title.alternative.pt_BR.fl_str_mv Journal of Clinical Virology
title Flower cells in patients with infective dermatitis associated with HTLV-1
spellingShingle Flower cells in patients with infective dermatitis associated with HTLV-1
Oliveira, Maria de Fátima Santos Paim de
HTLV-1 infection
Infective dermatitisassociatedwithHTLV-1
Adult T-cellleukemia/lymphoma
Flower cells
Skin diseasescausedbyHTLV-1
title_short Flower cells in patients with infective dermatitis associated with HTLV-1
title_full Flower cells in patients with infective dermatitis associated with HTLV-1
title_fullStr Flower cells in patients with infective dermatitis associated with HTLV-1
title_full_unstemmed Flower cells in patients with infective dermatitis associated with HTLV-1
title_sort Flower cells in patients with infective dermatitis associated with HTLV-1
author Oliveira, Maria de Fátima Santos Paim de
author_facet Oliveira, Maria de Fátima Santos Paim de
Vieira, Maria das Graças
Leite Primo, Janeusa Rita
Siqueira, Isadora C.
Carvalho Filho, Edgar Marcelino de
Farré, Lourdes
Fatal, Priscila Lima
Bittencourt, Achilea Candida Lisboa
author_role author
author2 Vieira, Maria das Graças
Leite Primo, Janeusa Rita
Siqueira, Isadora C.
Carvalho Filho, Edgar Marcelino de
Farré, Lourdes
Fatal, Priscila Lima
Bittencourt, Achilea Candida Lisboa
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Oliveira, Maria de Fátima Santos Paim de
Vieira, Maria das Graças
Leite Primo, Janeusa Rita
Siqueira, Isadora C.
Carvalho Filho, Edgar Marcelino de
Farré, Lourdes
Fatal, Priscila Lima
Bittencourt, Achilea Candida Lisboa
Oliveira, Maria de Fátima Santos Paim de
Vieira, Maria das Graças
Leite Primo, Janeusa Rita
Siqueira, Isadora C.
Carvalho Filho, Edgar Marcelino de
Farré, Lourdes
Fatal, Priscila Lima
Bittencourt, Achilea Candida Lisboa
dc.subject.por.fl_str_mv HTLV-1 infection
Infective dermatitisassociatedwithHTLV-1
Adult T-cellleukemia/lymphoma
Flower cells
Skin diseasescausedbyHTLV-1
topic HTLV-1 infection
Infective dermatitisassociatedwithHTLV-1
Adult T-cellleukemia/lymphoma
Flower cells
Skin diseasescausedbyHTLV-1
description Acesso restrito: Texto completo. p. 288-290
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2012-04-19T18:25:12Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/5673
dc.identifier.issn.none.fl_str_mv 1386-6532
dc.identifier.number.pt_BR.fl_str_mv v. 48, n. 4
identifier_str_mv 1386-6532
v. 48, n. 4
url http://www.repositorio.ufba.br/ri/handle/ri/5673
dc.language.iso.fl_str_mv eng
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dc.source.pt_BR.fl_str_mv DOI: 10.1016/j.jcv.2010.05.005
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