Clinical and Immunologic Evaluation of 31 Patients with Acute Schistosomiasis mansoni
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2002 |
| Outros Autores: | , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFBA |
| Texto Completo: | http://repositorio.ufba.br/ri/handle/ri/14550 |
Resumo: | Texto completo: acesso restrito. p.98-105 |
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Silva, AngelaJesus, Amelia Ribeiro deSantana, Luciana B.Magalhães, AndreaJesus, Adriana Almeida deAlmeida, Roque Pacheco deRêgo, Marco Antônio VasconcelosBurattini, Marcelo NascimentoPearce, Edward J.Carvalho Filho, Edgar Marcelino deSilva, AngelaJesus, Amelia Ribeiro deSantana, Luciana B.Magalhães, AndreaJesus, Adriana Almeida deAlmeida, Roque Pacheco deRêgo, Marco Antônio VasconcelosBurattini, Marcelo NascimentoPearce, Edward J.Carvalho Filho, Edgar Marcelino de2014-02-06T19:37:41Z20020022-1899http://repositorio.ufba.br/ri/handle/ri/14550v. 185, n. 1Texto completo: acesso restrito. p.98-105Thirty-one patients with acute schistosomiasis were evaluated clinically and immunologically. Cytokine levels were determined in peripheral blood mononuclear cell (PBMC) supernatants. Levels of total and antigen-specific IgE, tumor necrosis factor (TNF)–α, and immune complexes were measured in serum samples. Clinical findings included general symptoms, liver damage, pulmonary involvement, and pericarditis. All patients had eosinophilia. Immune complexes were detected in 55% of the patients (mean±SD, 7.8±7.6 μg Eq/mL) and were associated with cough, dyspnea, and abnormal chest radiographic findings. Levels (mean ± SD) of TNF-α (1349.3±767.6 pg/mL), interleukin (IL)–1 (2683±1270 pg/mL), and IL-6 (382 ± 52.3 pg/mL) were elevated in PBMC. Serum TNF-α levels were elevated in 87% of the patients and were associated with abdominal pain. Higher interferon-γ levels were detected in PBMC of patients with acute disease than in those of patients with chronic schistosomiasis; IL-5 levels were higher in those with chronic disease. Low IL-5 levels were associated with weight loss. Proinflammatory cytokines and immune complexes with low Th2 responses might explain the immunopathogenesis of acute schistosomiasis.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-02-03T15:22:14Z No. of bitstreams: 1 Angela Silva.pdf: 150155 bytes, checksum: b258ecad79a09b6802c5000bc6cf812a (MD5)Approved for entry into archive by Patricia Barroso (pbarroso@ufba.br) on 2014-02-06T19:37:41Z (GMT) No. of bitstreams: 1 Angela Silva.pdf: 150155 bytes, checksum: b258ecad79a09b6802c5000bc6cf812a (MD5)Made available in DSpace on 2014-02-06T19:37:41Z (GMT). No. of bitstreams: 1 Angela Silva.pdf: 150155 bytes, checksum: b258ecad79a09b6802c5000bc6cf812a (MD5) Previous issue date: 2002http://dx.doi.org/ 10.1086/324668reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAEsquistossomoseEsquistossomose mansoniClinical and Immunologic Evaluation of 31 Patients with Acute Schistosomiasis mansoniJournal of Infectious Diseasesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengLICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/14550/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52ORIGINALAngela Silva.pdfAngela Silva.pdfapplication/pdf150155https://repositorio.ufba.br/bitstream/ri/14550/1/Angela%20Silva.pdfb258ecad79a09b6802c5000bc6cf812aMD51TEXTAngela Silva.pdf.txtAngela Silva.pdf.txtExtracted texttext/plain41624https://repositorio.ufba.br/bitstream/ri/14550/3/Angela%20Silva.pdf.txt8eae692a2f96c9fd18ce3a1314b52daaMD53ri/145502022-07-05 14:02:48.16oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:02:48Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
| dc.title.pt_BR.fl_str_mv |
Clinical and Immunologic Evaluation of 31 Patients with Acute Schistosomiasis mansoni |
| dc.title.alternative.pt_BR.fl_str_mv |
Journal of Infectious Diseases |
| title |
Clinical and Immunologic Evaluation of 31 Patients with Acute Schistosomiasis mansoni |
| spellingShingle |
Clinical and Immunologic Evaluation of 31 Patients with Acute Schistosomiasis mansoni Silva, Angela Esquistossomose Esquistossomose mansoni |
| title_short |
Clinical and Immunologic Evaluation of 31 Patients with Acute Schistosomiasis mansoni |
| title_full |
Clinical and Immunologic Evaluation of 31 Patients with Acute Schistosomiasis mansoni |
| title_fullStr |
Clinical and Immunologic Evaluation of 31 Patients with Acute Schistosomiasis mansoni |
| title_full_unstemmed |
Clinical and Immunologic Evaluation of 31 Patients with Acute Schistosomiasis mansoni |
| title_sort |
Clinical and Immunologic Evaluation of 31 Patients with Acute Schistosomiasis mansoni |
| author |
Silva, Angela |
| author_facet |
Silva, Angela Jesus, Amelia Ribeiro de Santana, Luciana B. Magalhães, Andrea Jesus, Adriana Almeida de Almeida, Roque Pacheco de Rêgo, Marco Antônio Vasconcelos Burattini, Marcelo Nascimento Pearce, Edward J. Carvalho Filho, Edgar Marcelino de |
| author_role |
author |
| author2 |
Jesus, Amelia Ribeiro de Santana, Luciana B. Magalhães, Andrea Jesus, Adriana Almeida de Almeida, Roque Pacheco de Rêgo, Marco Antônio Vasconcelos Burattini, Marcelo Nascimento Pearce, Edward J. Carvalho Filho, Edgar Marcelino de |
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author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Silva, Angela Jesus, Amelia Ribeiro de Santana, Luciana B. Magalhães, Andrea Jesus, Adriana Almeida de Almeida, Roque Pacheco de Rêgo, Marco Antônio Vasconcelos Burattini, Marcelo Nascimento Pearce, Edward J. Carvalho Filho, Edgar Marcelino de Silva, Angela Jesus, Amelia Ribeiro de Santana, Luciana B. Magalhães, Andrea Jesus, Adriana Almeida de Almeida, Roque Pacheco de Rêgo, Marco Antônio Vasconcelos Burattini, Marcelo Nascimento Pearce, Edward J. Carvalho Filho, Edgar Marcelino de |
| dc.subject.por.fl_str_mv |
Esquistossomose Esquistossomose mansoni |
| topic |
Esquistossomose Esquistossomose mansoni |
| description |
Texto completo: acesso restrito. p.98-105 |
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2002 |
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2002 |
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2014-02-06T19:37:41Z |
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0022-1899 |
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v. 185, n. 1 |
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0022-1899 v. 185, n. 1 |
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