The effect of the association of NIR laser therapy BMPs, and guided bone regeneration on tibial fractures treated with wire osteosynthesis: raman spectroscopy study

Detalhes bibliográficos
Autor(a) principal: Lopes, Cibelle Barbosa
Data de Publicação: 2007
Outros Autores: Pacheco, Marcos Tadeu Tavares, Silveira Jr., L., Duarte, J., Cangussu, Maria Cristina Teixeira, Pinheiro, A. L. B.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/15954
Resumo: Texto completo: acesso restrito. p. 125-130
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spelling Lopes, Cibelle BarbosaPacheco, Marcos Tadeu TavaresSilveira Jr., L.Duarte, J.Cangussu, Maria Cristina TeixeiraPinheiro, A. L. B.Lopes, Cibelle BarbosaPacheco, Marcos Tadeu TavaresSilveira Jr., L.Duarte, J.Cangussu, Maria Cristina TeixeiraPinheiro, A. L. B.2014-09-09T15:46:45Z20071011-1344http://repositorio.ufba.br/ri/handle/ri/15954v. 89, n. 2-3Texto completo: acesso restrito. p. 125-130Bone fractures are lesions of different etiology; may be associated or not to bone losses; and have different options for treatment, such as the use of biomaterials, guided bone regeneration, techniques considered effective on improving bone repair. Laser therapy has also been shown to improve bone healing on several models. The association of these three techniques has been well documented by our group using different models. This study aimed to assess, through Raman spectroscopy, the incorporation of calcium hydroxyapatite (CHA ∼ 958 cm−1) on the repair of complete tibial fractures in rabbits treated with wire osteosynthesis (WO); treated or not with laser therapy; and associated or not with the use of BMPs and/or Guided Bone Regeneration. Complete tibial fractures were created in 12 animals that were divided into four groups: WO; WO + BMPs; WO + laser therapy; and WO + BMPs + laser therapy. Irradiation started immediately after surgery; was repeated at every other day during 2 weeks; and was carried out with λ 790 nm laser light (4 J/cm2 per point, 40 mW, φ ∼ 0.5 cm2, 16 J per session). Animal death occurred after 30 days. Raman spectroscopy was performed at both the surface and the depth of the fracture site. Statistical analysis showed significant difference on the concentrations of CHA between surface and depth. The analysis in each of the areas showed at the depth of the fracture significant differences between all treatment groups (p < 0.0001). Significant differences were also seen between WO + BMPs + laser therapy and WO (p < 0.001) and WO + laser therapy (p < 0.001). At the surface, significant difference was seen only between the treatment groups and the non-fractured subjects (p = 0.0001). However, no significant difference was seen between the treatment groups (p = 0.14). It is concluded that the use of NIR laser therapy associated to BMPs and GBR was effective in improving bone healing on the fractured bones as a result of the increasing deposition of CHA measured by Raman spectroscopy.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-12-18T14:17:42Z No. of bitstreams: 1 1-s2.0-S101113440700139X-main.pdf: 379361 bytes, checksum: b7929d662fe7750c2f164855cfad49e9 (MD5)Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2014-09-09T15:46:45Z (GMT) No. of bitstreams: 1 1-s2.0-S101113440700139X-main.pdf: 379361 bytes, checksum: b7929d662fe7750c2f164855cfad49e9 (MD5)Made available in DSpace on 2014-09-09T15:46:45Z (GMT). No. of bitstreams: 1 1-s2.0-S101113440700139X-main.pdf: 379361 bytes, checksum: b7929d662fe7750c2f164855cfad49e9 (MD5) Previous issue date: 2007http://dx.doi.org/10.1016/j.jphotobiol.2007.09.011reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBABone healingInternal rigid fixationLaser therapyLLLTThe effect of the association of NIR laser therapy BMPs, and guided bone regeneration on tibial fractures treated with wire osteosynthesis: raman spectroscopy studyJournal of Photochemistry and Photobiology B: Biologyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINAL1-s2.0-S101113440700139X-main.pdf1-s2.0-S101113440700139X-main.pdfapplication/pdf379361https://repositorio.ufba.br/bitstream/ri/15954/1/1-s2.0-S101113440700139X-main.pdfb7929d662fe7750c2f164855cfad49e9MD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/15954/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXT1-s2.0-S101113440700139X-main.pdf.txt1-s2.0-S101113440700139X-main.pdf.txtExtracted texttext/plain27840https://repositorio.ufba.br/bitstream/ri/15954/3/1-s2.0-S101113440700139X-main.pdf.txta22121db551a73efde5e1e7967a20702MD53ri/159542022-07-05 14:02:48.557oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:02:48Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv The effect of the association of NIR laser therapy BMPs, and guided bone regeneration on tibial fractures treated with wire osteosynthesis: raman spectroscopy study
dc.title.alternative.pt_BR.fl_str_mv Journal of Photochemistry and Photobiology B: Biology
title The effect of the association of NIR laser therapy BMPs, and guided bone regeneration on tibial fractures treated with wire osteosynthesis: raman spectroscopy study
spellingShingle The effect of the association of NIR laser therapy BMPs, and guided bone regeneration on tibial fractures treated with wire osteosynthesis: raman spectroscopy study
Lopes, Cibelle Barbosa
Bone healing
Internal rigid fixation
Laser therapy
LLLT
title_short The effect of the association of NIR laser therapy BMPs, and guided bone regeneration on tibial fractures treated with wire osteosynthesis: raman spectroscopy study
title_full The effect of the association of NIR laser therapy BMPs, and guided bone regeneration on tibial fractures treated with wire osteosynthesis: raman spectroscopy study
title_fullStr The effect of the association of NIR laser therapy BMPs, and guided bone regeneration on tibial fractures treated with wire osteosynthesis: raman spectroscopy study
title_full_unstemmed The effect of the association of NIR laser therapy BMPs, and guided bone regeneration on tibial fractures treated with wire osteosynthesis: raman spectroscopy study
title_sort The effect of the association of NIR laser therapy BMPs, and guided bone regeneration on tibial fractures treated with wire osteosynthesis: raman spectroscopy study
author Lopes, Cibelle Barbosa
author_facet Lopes, Cibelle Barbosa
Pacheco, Marcos Tadeu Tavares
Silveira Jr., L.
Duarte, J.
Cangussu, Maria Cristina Teixeira
Pinheiro, A. L. B.
author_role author
author2 Pacheco, Marcos Tadeu Tavares
Silveira Jr., L.
Duarte, J.
Cangussu, Maria Cristina Teixeira
Pinheiro, A. L. B.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Lopes, Cibelle Barbosa
Pacheco, Marcos Tadeu Tavares
Silveira Jr., L.
Duarte, J.
Cangussu, Maria Cristina Teixeira
Pinheiro, A. L. B.
Lopes, Cibelle Barbosa
Pacheco, Marcos Tadeu Tavares
Silveira Jr., L.
Duarte, J.
Cangussu, Maria Cristina Teixeira
Pinheiro, A. L. B.
dc.subject.por.fl_str_mv Bone healing
Internal rigid fixation
Laser therapy
LLLT
topic Bone healing
Internal rigid fixation
Laser therapy
LLLT
description Texto completo: acesso restrito. p. 125-130
publishDate 2007
dc.date.issued.fl_str_mv 2007
dc.date.accessioned.fl_str_mv 2014-09-09T15:46:45Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/15954
dc.identifier.issn.none.fl_str_mv 1011-1344
dc.identifier.number.pt_BR.fl_str_mv v. 89, n. 2-3
identifier_str_mv 1011-1344
v. 89, n. 2-3
url http://repositorio.ufba.br/ri/handle/ri/15954
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1016/j.jphotobiol.2007.09.011
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