Brain magnetic resonance imaging white matter lesions are frequent in HTLV-I carriers and do not discriminate from HAM/TSP
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2007 |
| Outros Autores: | , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFBA |
| Texto Completo: | http://repositorio.ufba.br/ri/handle/ri/14393 |
Resumo: | Texto completo: acesso restrito. p. 1499-1503 |
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Morgan, Daniel J.Caskey, Marina F.Lima, Cristiane AbbehusenOliveira Filho, JamaryAraújo, CésarPorto, Maria Aurélia da FonsecaSantos, Silvane Maria BragaOrge, Gloria O.Joia, Maria JoseMuniz, André Luís NunesSiqueira, IsadoraGlesby, Marshall J.Carvalho Filho, Edgar Marcelino deMorgan, Daniel J.Caskey, Marina F.Lima, Cristiane AbbehusenOliveira Filho, JamaryAraújo, CésarPorto, Maria Aurélia da FonsecaSantos, Silvane Maria BragaOrge, Gloria O.Joia, Maria JoseMuniz, André Luís NunesSiqueira, IsadoraGlesby, Marshall J.Carvalho Filho, Edgar Marcelino de2014-01-20T16:13:51Z20070889-2229http://repositorio.ufba.br/ri/handle/ri/14393v. 23, n. 12Texto completo: acesso restrito. p. 1499-1503Human T lymphotropic virus (HTLV)-I is known to cause HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and other pronounced disease in less than 4% of those infected. However, evidence is accumulating that a proportion of HTLV-I carriers have neurological and urological symptoms without fulfilling criteria for HAM/TSP. Brain white matter (WM) lesions on magnetic resonance imaging (MRI) are frequently seen in HAM/TSP. HTLV-I carriers with MRI scans for other neurological diagnoses have WM lesions more frequently than expected. We studied 10 patients with HAM/TSP and 20 HTLV-I carriers without overt neurological disease and evaluated clinical characteristics, viral load, total, small, large, confluent WM lesion number, and lesion volume on MRI. Cerebral WM lesions were found in of 85% of HTLV-I carriers and 80% of HAM/TSP patients. Lesion number, size or location was no different between carriers and HAM/TSP. Cognitive function was lower in HAM/TSP (p = 0.045) but did not correlate with WM lesion number. Viral load and peripheral blood mononuclear cell interferon production correlated positively (p = 0.001) but did not correlate with lesion number or volume. Conventional brain MRI frequently shows WM lesions in HTLV-I-infected individuals suggesting potential early central nervous system inflammation with rare development of progressive disease.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-01-07T11:28:52Z No. of bitstreams: 1 aid%2E2007%2E0077.pdf: 131072 bytes, checksum: 0a4f1283b902c44118d245e94f1994b2 (MD5)Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2014-01-20T16:13:51Z (GMT) No. of bitstreams: 1 aid%2E2007%2E0077.pdf: 131072 bytes, checksum: 0a4f1283b902c44118d245e94f1994b2 (MD5)Made available in DSpace on 2014-01-20T16:13:51Z (GMT). No. of bitstreams: 1 aid%2E2007%2E0077.pdf: 131072 bytes, checksum: 0a4f1283b902c44118d245e94f1994b2 (MD5) Previous issue date: 2007http://dx.doi.org/10.1089/aid.2007.0077reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAMagnetic Resonance ImagingHuman T-lymphotropic virus 1Brain magnetic resonance imaging white matter lesions are frequent in HTLV-I carriers and do not discriminate from HAM/TSPAIDS Research and Human Retrovirusesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALaid%2E2007%2E0077.pdfaid%2E2007%2E0077.pdfapplication/pdf131072https://repositorio.ufba.br/bitstream/ri/14393/1/aid%252E2007%252E0077.pdf0a4f1283b902c44118d245e94f1994b2MD51LICENSElicense.txtlicense.txttext/plain1345https://repositorio.ufba.br/bitstream/ri/14393/2/license.txtff6eaa8b858ea317fded99f125f5fcd0MD52TEXTaid%2E2007%2E0077.pdf.txtaid%2E2007%2E0077.pdf.txtExtracted texttext/plain25199https://repositorio.ufba.br/bitstream/ri/14393/3/aid%252E2007%252E0077.pdf.txt44428fed1d1cd6b759b56658d2afb487MD53ri/143932022-07-05 14:02:57.269oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:02:57Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
| dc.title.pt_BR.fl_str_mv |
Brain magnetic resonance imaging white matter lesions are frequent in HTLV-I carriers and do not discriminate from HAM/TSP |
| dc.title.alternative.pt_BR.fl_str_mv |
AIDS Research and Human Retroviruses |
| title |
Brain magnetic resonance imaging white matter lesions are frequent in HTLV-I carriers and do not discriminate from HAM/TSP |
| spellingShingle |
Brain magnetic resonance imaging white matter lesions are frequent in HTLV-I carriers and do not discriminate from HAM/TSP Morgan, Daniel J. Magnetic Resonance Imaging Human T-lymphotropic virus 1 |
| title_short |
Brain magnetic resonance imaging white matter lesions are frequent in HTLV-I carriers and do not discriminate from HAM/TSP |
| title_full |
Brain magnetic resonance imaging white matter lesions are frequent in HTLV-I carriers and do not discriminate from HAM/TSP |
| title_fullStr |
Brain magnetic resonance imaging white matter lesions are frequent in HTLV-I carriers and do not discriminate from HAM/TSP |
| title_full_unstemmed |
Brain magnetic resonance imaging white matter lesions are frequent in HTLV-I carriers and do not discriminate from HAM/TSP |
| title_sort |
Brain magnetic resonance imaging white matter lesions are frequent in HTLV-I carriers and do not discriminate from HAM/TSP |
| author |
Morgan, Daniel J. |
| author_facet |
Morgan, Daniel J. Caskey, Marina F. Lima, Cristiane Abbehusen Oliveira Filho, Jamary Araújo, César Porto, Maria Aurélia da Fonseca Santos, Silvane Maria Braga Orge, Gloria O. Joia, Maria Jose Muniz, André Luís Nunes Siqueira, Isadora Glesby, Marshall J. Carvalho Filho, Edgar Marcelino de |
| author_role |
author |
| author2 |
Caskey, Marina F. Lima, Cristiane Abbehusen Oliveira Filho, Jamary Araújo, César Porto, Maria Aurélia da Fonseca Santos, Silvane Maria Braga Orge, Gloria O. Joia, Maria Jose Muniz, André Luís Nunes Siqueira, Isadora Glesby, Marshall J. Carvalho Filho, Edgar Marcelino de |
| author2_role |
author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Morgan, Daniel J. Caskey, Marina F. Lima, Cristiane Abbehusen Oliveira Filho, Jamary Araújo, César Porto, Maria Aurélia da Fonseca Santos, Silvane Maria Braga Orge, Gloria O. Joia, Maria Jose Muniz, André Luís Nunes Siqueira, Isadora Glesby, Marshall J. Carvalho Filho, Edgar Marcelino de Morgan, Daniel J. Caskey, Marina F. Lima, Cristiane Abbehusen Oliveira Filho, Jamary Araújo, César Porto, Maria Aurélia da Fonseca Santos, Silvane Maria Braga Orge, Gloria O. Joia, Maria Jose Muniz, André Luís Nunes Siqueira, Isadora Glesby, Marshall J. Carvalho Filho, Edgar Marcelino de |
| dc.subject.por.fl_str_mv |
Magnetic Resonance Imaging Human T-lymphotropic virus 1 |
| topic |
Magnetic Resonance Imaging Human T-lymphotropic virus 1 |
| description |
Texto completo: acesso restrito. p. 1499-1503 |
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2007 |
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2007 |
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2014-01-20T16:13:51Z |
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info:eu-repo/semantics/publishedVersion |
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http://repositorio.ufba.br/ri/handle/ri/14393 |
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0889-2229 |
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v. 23, n. 12 |
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0889-2229 v. 23, n. 12 |
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http://repositorio.ufba.br/ri/handle/ri/14393 |
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