HLA class II polymorphism in Brazilian populations

Detalhes bibliográficos
Autor(a) principal: Alves, Crésio de Aragão Dantas
Data de Publicação: 2005
Outros Autores: Souza, Thaisa, Veiga, Sâmia, Toralles, Maria Betânia Pereira, Lemaire, Denise Carneiro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/1501
Resumo: p. 140 - 149
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spelling Alves, Crésio de Aragão DantasSouza, ThaisaVeiga, SâmiaToralles, Maria Betânia PereiraLemaire, Denise CarneiroAlves, Crésio de Aragão DantasSouza, ThaisaVeiga, SâmiaToralles, Maria Betânia PereiraLemaire, Denise Carneiro2011-06-14T12:53:01Z2011-06-14T12:53:01Z20052236-5222http://www.repositorio.ufba.br/ri/handle/ri/1501v. 4, n. 2p. 140 - 149The investigation of the distribution and frequency of HLA (Human Leukocyte Antigen) genes in presumably healthy populations is important to evaluate the participation of these genes in the susceptibility and protection against diseases, to evaluate the genetic origins of populations and to aid in the practice of transplantations. The advances in molecular biology has allowed a better understanding of this system. In addition, information about the HLA class II molecules, such as their mechanism of action, function, and genetic polymorphism, granted their use as markers for ethnic composition of a population and even of individual distinction. The HLA class II genes appear to be associated with some racial/ ethnic groups more than others. By using these genetic characteristics, it may be possible to demonstrate, for example, the degree of admixture of Caucasians, Africans and Amerindians that marks in a significant way the origin of the Brazilian population. It also clarifies some aspects of the ancestry of this population and helps the performance of population studies with the objectives to obtain information related to the history and formation features, migration and composition of theses groups, in conformity with local particularities. The relevance of this theme is the frequency of HLA class II antigens, alleles and haplotypes in the Brazilian populations.Submitted by RI Repositorio (repositorio@ufba.br) on 2011-06-14T12:53:01Z No. of bitstreams: 1 3062 M.pdf: 108009 bytes, checksum: c08a939960b6818dea1b3f053abbc0b9 (MD5)Made available in DSpace on 2011-06-14T12:53:01Z (GMT). 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dc.title.pt_BR.fl_str_mv HLA class II polymorphism in Brazilian populations
dc.title.alternative.pt_BR.fl_str_mv Revista de Ciências Médicas e Biológicas
title HLA class II polymorphism in Brazilian populations
spellingShingle HLA class II polymorphism in Brazilian populations
Alves, Crésio de Aragão Dantas
HLA - Brazilian population
major histocompatibility complex
title_short HLA class II polymorphism in Brazilian populations
title_full HLA class II polymorphism in Brazilian populations
title_fullStr HLA class II polymorphism in Brazilian populations
title_full_unstemmed HLA class II polymorphism in Brazilian populations
title_sort HLA class II polymorphism in Brazilian populations
author Alves, Crésio de Aragão Dantas
author_facet Alves, Crésio de Aragão Dantas
Souza, Thaisa
Veiga, Sâmia
Toralles, Maria Betânia Pereira
Lemaire, Denise Carneiro
author_role author
author2 Souza, Thaisa
Veiga, Sâmia
Toralles, Maria Betânia Pereira
Lemaire, Denise Carneiro
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Alves, Crésio de Aragão Dantas
Souza, Thaisa
Veiga, Sâmia
Toralles, Maria Betânia Pereira
Lemaire, Denise Carneiro
Alves, Crésio de Aragão Dantas
Souza, Thaisa
Veiga, Sâmia
Toralles, Maria Betânia Pereira
Lemaire, Denise Carneiro
dc.subject.por.fl_str_mv HLA - Brazilian population
major histocompatibility complex
topic HLA - Brazilian population
major histocompatibility complex
description p. 140 - 149
publishDate 2005
dc.date.issued.fl_str_mv 2005
dc.date.accessioned.fl_str_mv 2011-06-14T12:53:01Z
dc.date.available.fl_str_mv 2011-06-14T12:53:01Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/1501
dc.identifier.issn.none.fl_str_mv 2236-5222
dc.identifier.number.pt_BR.fl_str_mv v. 4, n. 2
identifier_str_mv 2236-5222
v. 4, n. 2
url http://www.repositorio.ufba.br/ri/handle/ri/1501
dc.language.iso.fl_str_mv eng
language eng
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reponame_str Repositório Institucional da UFBA
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