HLA class II polymorphism in Brazilian populations
Autor(a) principal: | |
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Data de Publicação: | 2005 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/1501 |
Resumo: | p. 140 - 149 |
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Alves, Crésio de Aragão DantasSouza, ThaisaVeiga, SâmiaToralles, Maria Betânia PereiraLemaire, Denise CarneiroAlves, Crésio de Aragão DantasSouza, ThaisaVeiga, SâmiaToralles, Maria Betânia PereiraLemaire, Denise Carneiro2011-06-14T12:53:01Z2011-06-14T12:53:01Z20052236-5222http://www.repositorio.ufba.br/ri/handle/ri/1501v. 4, n. 2p. 140 - 149The investigation of the distribution and frequency of HLA (Human Leukocyte Antigen) genes in presumably healthy populations is important to evaluate the participation of these genes in the susceptibility and protection against diseases, to evaluate the genetic origins of populations and to aid in the practice of transplantations. The advances in molecular biology has allowed a better understanding of this system. In addition, information about the HLA class II molecules, such as their mechanism of action, function, and genetic polymorphism, granted their use as markers for ethnic composition of a population and even of individual distinction. The HLA class II genes appear to be associated with some racial/ ethnic groups more than others. By using these genetic characteristics, it may be possible to demonstrate, for example, the degree of admixture of Caucasians, Africans and Amerindians that marks in a significant way the origin of the Brazilian population. It also clarifies some aspects of the ancestry of this population and helps the performance of population studies with the objectives to obtain information related to the history and formation features, migration and composition of theses groups, in conformity with local particularities. The relevance of this theme is the frequency of HLA class II antigens, alleles and haplotypes in the Brazilian populations.Submitted by RI Repositorio (repositorio@ufba.br) on 2011-06-14T12:53:01Z No. of bitstreams: 1 3062 M.pdf: 108009 bytes, checksum: c08a939960b6818dea1b3f053abbc0b9 (MD5)Made available in DSpace on 2011-06-14T12:53:01Z (GMT). No. of bitstreams: 1 3062 M.pdf: 108009 bytes, checksum: c08a939960b6818dea1b3f053abbc0b9 (MD5) Previous issue date: 2005SalvadorHLA - Brazilian populationmajor histocompatibility complexHLA class II polymorphism in Brazilian populationsRevista de Ciências Médicas e Biológicasinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAinfo:eu-repo/semantics/openAccessORIGINAL3062 M.pdf3062 M.pdfapplication/pdf108009https://repositorio.ufba.br/bitstream/ri/1501/1/3062%20M.pdfc08a939960b6818dea1b3f053abbc0b9MD51LICENSElicense.txtlicense.txttext/plain1898https://repositorio.ufba.br/bitstream/ri/1501/2/license.txt387537f06d2f70936190cd870328f1f1MD52TEXT3062 M.pdf.txt3062 M.pdf.txtExtracted texttext/plain32138https://repositorio.ufba.br/bitstream/ri/1501/3/3062%20M.pdf.txte529e09005e23103308c1b7b90d95d11MD53ri/15012022-08-08 13:17:27.369oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-08-08T16:17:27Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
dc.title.pt_BR.fl_str_mv |
HLA class II polymorphism in Brazilian populations |
dc.title.alternative.pt_BR.fl_str_mv |
Revista de Ciências Médicas e Biológicas |
title |
HLA class II polymorphism in Brazilian populations |
spellingShingle |
HLA class II polymorphism in Brazilian populations Alves, Crésio de Aragão Dantas HLA - Brazilian population major histocompatibility complex |
title_short |
HLA class II polymorphism in Brazilian populations |
title_full |
HLA class II polymorphism in Brazilian populations |
title_fullStr |
HLA class II polymorphism in Brazilian populations |
title_full_unstemmed |
HLA class II polymorphism in Brazilian populations |
title_sort |
HLA class II polymorphism in Brazilian populations |
author |
Alves, Crésio de Aragão Dantas |
author_facet |
Alves, Crésio de Aragão Dantas Souza, Thaisa Veiga, Sâmia Toralles, Maria Betânia Pereira Lemaire, Denise Carneiro |
author_role |
author |
author2 |
Souza, Thaisa Veiga, Sâmia Toralles, Maria Betânia Pereira Lemaire, Denise Carneiro |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Alves, Crésio de Aragão Dantas Souza, Thaisa Veiga, Sâmia Toralles, Maria Betânia Pereira Lemaire, Denise Carneiro Alves, Crésio de Aragão Dantas Souza, Thaisa Veiga, Sâmia Toralles, Maria Betânia Pereira Lemaire, Denise Carneiro |
dc.subject.por.fl_str_mv |
HLA - Brazilian population major histocompatibility complex |
topic |
HLA - Brazilian population major histocompatibility complex |
description |
p. 140 - 149 |
publishDate |
2005 |
dc.date.issued.fl_str_mv |
2005 |
dc.date.accessioned.fl_str_mv |
2011-06-14T12:53:01Z |
dc.date.available.fl_str_mv |
2011-06-14T12:53:01Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.repositorio.ufba.br/ri/handle/ri/1501 |
dc.identifier.issn.none.fl_str_mv |
2236-5222 |
dc.identifier.number.pt_BR.fl_str_mv |
v. 4, n. 2 |
identifier_str_mv |
2236-5222 v. 4, n. 2 |
url |
http://www.repositorio.ufba.br/ri/handle/ri/1501 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
dc.source.none.fl_str_mv |
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Universidade Federal da Bahia (UFBA) |
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UFBA |
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Repositório Institucional da UFBA |
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Repositório Institucional da UFBA |
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