Clinical manifestations of Hepatitis B: its association with serum profile of cytokine genetic polymorphism

Detalhes bibliográficos
Autor(a) principal: Campos, Maurício de Souza
Data de Publicação: 2013
Outros Autores: Schinoni, Maria Isabel, Freire, Songeli Menezes
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/23121
Resumo: Objective: This systematic review aims to review the correlation among the genetic polymorphism of cytokine, production and clinical presentation of these serum proteins in forty seven (47)hepatitis B chronic. Methodology: For this we conducted a systematic review of articles obtained by searching the databases Journals Portal CAPES and Pub Med The papers selected were published between the years 200 and 2013. We used the following descriptors: 1. Chronic hepatitis B, 2. Cytokine gene polymorphism 3. Anti-hepatitis B / genetics, 4. Hepatitis B virus / genetics. Results: the articles found in the search, twenty five (25), which were used in this review. Conclusions: The research on the correlation between the genetic polymorphism of cytokine production of these serum and clinical presentation of chronic hepatitis B is still incipient, although this may elucidate the immunological mechanisms responsible for viral clearance and the chronicity of the infection.
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spelling Campos, Maurício de SouzaSchinoni, Maria IsabelFreire, Songeli MenezesCampos, Maurício de SouzaSchinoni, Maria IsabelFreire, Songeli Menezes2017-06-19T18:33:14Z2017-06-19T18:33:14Z2013-12Rev. Ciênc. Méd. Biol., Salvador, v.12, especial, p.501-505, dez.2013.2236-5222http://repositorio.ufba.br/ri/handle/ri/23121v.12Objective: This systematic review aims to review the correlation among the genetic polymorphism of cytokine, production and clinical presentation of these serum proteins in forty seven (47)hepatitis B chronic. Methodology: For this we conducted a systematic review of articles obtained by searching the databases Journals Portal CAPES and Pub Med The papers selected were published between the years 200 and 2013. We used the following descriptors: 1. Chronic hepatitis B, 2. Cytokine gene polymorphism 3. Anti-hepatitis B / genetics, 4. Hepatitis B virus / genetics. Results: the articles found in the search, twenty five (25), which were used in this review. Conclusions: The research on the correlation between the genetic polymorphism of cytokine production of these serum and clinical presentation of chronic hepatitis B is still incipient, although this may elucidate the immunological mechanisms responsible for viral clearance and the chronicity of the infection.Objetivo: Essa revisão sistemática teve como objetivo revisar a correlação entre o polimorfismo genético das citocinas com a produção sérica dessas e a apresentação clínica da Hepatite B crônica. Metodologia: Foi realizada uma atualização do estado da arte com artigos obtidos por meio de busca nos bancos de dados do Portal de Periódicos da CAPES e PubMed. Os artigos científicos selecionados foram publicados entre os anos de 2000 e 2013. Foram utilizados os seguintes descritores: 1. Hepatite B crônica, 2. Polimorfismo genético de citocinas; 3.Anticorpos anti-hepatite B/genética, 4. Vírus da Hepatite B/genética. Resultados: Dos artigos encontrados na busca, foram selecionados vinte e cinco (25), os quais foram usados nessa revisão. Conclusão: A pesquisa acerca da correlação entre o polimorfismo genético das citocinas com a produção sérica dessas e a apresentação clínica da Hepatite B crônica ainda é insipiente, embora isso possa elucidar os mecanismos imunológicos responsáveis pela eliminação viral e pela cronificação da infecção.Submitted by ROBERTO PAULO CORREIA DE ARAÚJO (ppgorgsistem@ufba.br) on 2017-06-19T18:33:13Z No. of bitstreams: 1 16_v.12_esp..pdf: 302592 bytes, checksum: 6255c38ee69ce9ec35bd961131dad1c9 (MD5)Made available in DSpace on 2017-06-19T18:33:14Z (GMT). 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dc.title.pt_BR.fl_str_mv Clinical manifestations of Hepatitis B: its association with serum profile of cytokine genetic polymorphism
dc.title.alternative.pt_BR.fl_str_mv Revista de Ciências Médicas e Biológicas
title Clinical manifestations of Hepatitis B: its association with serum profile of cytokine genetic polymorphism
spellingShingle Clinical manifestations of Hepatitis B: its association with serum profile of cytokine genetic polymorphism
Campos, Maurício de Souza
Hepatite B Crônica
Polimorfismo Genético de Citocinas
title_short Clinical manifestations of Hepatitis B: its association with serum profile of cytokine genetic polymorphism
title_full Clinical manifestations of Hepatitis B: its association with serum profile of cytokine genetic polymorphism
title_fullStr Clinical manifestations of Hepatitis B: its association with serum profile of cytokine genetic polymorphism
title_full_unstemmed Clinical manifestations of Hepatitis B: its association with serum profile of cytokine genetic polymorphism
title_sort Clinical manifestations of Hepatitis B: its association with serum profile of cytokine genetic polymorphism
author Campos, Maurício de Souza
author_facet Campos, Maurício de Souza
Schinoni, Maria Isabel
Freire, Songeli Menezes
author_role author
author2 Schinoni, Maria Isabel
Freire, Songeli Menezes
author2_role author
author
dc.contributor.author.fl_str_mv Campos, Maurício de Souza
Schinoni, Maria Isabel
Freire, Songeli Menezes
Campos, Maurício de Souza
Schinoni, Maria Isabel
Freire, Songeli Menezes
dc.subject.por.fl_str_mv Hepatite B Crônica
Polimorfismo Genético de Citocinas
topic Hepatite B Crônica
Polimorfismo Genético de Citocinas
description Objective: This systematic review aims to review the correlation among the genetic polymorphism of cytokine, production and clinical presentation of these serum proteins in forty seven (47)hepatitis B chronic. Methodology: For this we conducted a systematic review of articles obtained by searching the databases Journals Portal CAPES and Pub Med The papers selected were published between the years 200 and 2013. We used the following descriptors: 1. Chronic hepatitis B, 2. Cytokine gene polymorphism 3. Anti-hepatitis B / genetics, 4. Hepatitis B virus / genetics. Results: the articles found in the search, twenty five (25), which were used in this review. Conclusions: The research on the correlation between the genetic polymorphism of cytokine production of these serum and clinical presentation of chronic hepatitis B is still incipient, although this may elucidate the immunological mechanisms responsible for viral clearance and the chronicity of the infection.
publishDate 2013
dc.date.issued.fl_str_mv 2013-12
dc.date.accessioned.fl_str_mv 2017-06-19T18:33:14Z
dc.date.available.fl_str_mv 2017-06-19T18:33:14Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.citation.fl_str_mv Rev. Ciênc. Méd. Biol., Salvador, v.12, especial, p.501-505, dez.2013.
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/23121
dc.identifier.issn.none.fl_str_mv 2236-5222
dc.identifier.number.pt_BR.fl_str_mv v.12
identifier_str_mv Rev. Ciênc. Méd. Biol., Salvador, v.12, especial, p.501-505, dez.2013.
2236-5222
v.12
url http://repositorio.ufba.br/ri/handle/ri/23121
dc.language.iso.fl_str_mv por
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dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Instituto de Ciências da Saúde/ Universidade Federal da Bahia
dc.publisher.country.fl_str_mv Brasil
publisher.none.fl_str_mv Instituto de Ciências da Saúde/ Universidade Federal da Bahia
dc.source.pt_BR.fl_str_mv http://www.portalseer.ufba.br/index.php/cmbio/article/view/9200/6763
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