Osteoarticular manifestations as initial presentation of acute leukemias in children and adolescents in Bahia, Brazil

Detalhes bibliográficos
Autor(a) principal: Robazzi, Teresa Cristina Martins Vicente
Data de Publicação: 2007
Outros Autores: Barreto, José Henrique Silva, Silva, Luciana R., Santiago, Mittermayer Barreto, Mendonça, Núbia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/14400
Resumo: Texto completo: acesso restrito. p. 622-626
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spelling Robazzi, Teresa Cristina Martins VicenteBarreto, José Henrique SilvaSilva, Luciana R.Santiago, Mittermayer BarretoMendonça, NúbiaRobazzi, Teresa Cristina Martins VicenteBarreto, José Henrique SilvaSilva, Luciana R.Santiago, Mittermayer BarretoMendonça, Núbia2014-01-21T11:18:29Z20071077-4114http://repositorio.ufba.br/ri/handle/ri/14400v. 29, n. 9Texto completo: acesso restrito. p. 622-626Objective: This study was to determine the prevalence and characteristics of the osteoarticular manifestations on initial clinical presentation of acute leukemias (ALs) on childhood in the state of Bahia, Brazil. Materials and Methods: This retrospective study assessed the medical records of 406 patients with AL from January 1995 to December 2004. Results: Acute lymphocytic leukemia (ALL) was diagnosed in 313 (77.1%) patients and acute myeloid leukemia (AML), in 93 (22.9%) patients, including 241 males (59.4%) and 165 females (40.6%). Age ranged from 9 months to 15 years (average: 6.18 y). The most common presenting features were fever (18.5%), musculoskeletal diffuse tenderness (15.0%), pallor (11.4%), and leg tenderness (5.7%). Prior referral to our center, the most frequent initial diagnosis was anemia (15.8%), leukemia (15.0%), amygdalitis (3.7%), and rheumatic fever (2.7%). Osteoarticular manifestations were found on 54.7% of the patients with AL, with a higher frequency among patients between 1 and 9 years of age (58.7%, P=0.0007). The presence of joint tenderness (16.2% in ALL×5.4% in AML), arthritis (26.6% in ALL×9.7 in AML), bone tenderness (26.1% in ALL×16.1% in AML), limb tenderness (49.5% in ALL×25.8% in AML), and antalgic gait (32.8% in ALL×9.7% in AML) had higher prevalence on ALL. The large joints, chiefly the knees (10.6%), ankles (9.4%), elbows (4.4%), and shoulders (3.6%) were more often affected. Conclusions: AL should be considered on the differential diagnosis of osteoarticular symptoms of unknown etiology in children.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-01-21T11:18:29Z No. of bitstreams: 1 00043426-200709000-00009.pdf: 131072 bytes, checksum: e72f51ce46def6b00e814444cabe8870 (MD5)Made available in DSpace on 2014-01-21T11:18:29Z (GMT). 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dc.title.pt_BR.fl_str_mv Osteoarticular manifestations as initial presentation of acute leukemias in children and adolescents in Bahia, Brazil
dc.title.alternative.pt_BR.fl_str_mv Journal of Pediatric Hematology/Oncology
title Osteoarticular manifestations as initial presentation of acute leukemias in children and adolescents in Bahia, Brazil
spellingShingle Osteoarticular manifestations as initial presentation of acute leukemias in children and adolescents in Bahia, Brazil
Robazzi, Teresa Cristina Martins Vicente
Acute leukemias
Osteoarticular manifestations
Children and adolescent
title_short Osteoarticular manifestations as initial presentation of acute leukemias in children and adolescents in Bahia, Brazil
title_full Osteoarticular manifestations as initial presentation of acute leukemias in children and adolescents in Bahia, Brazil
title_fullStr Osteoarticular manifestations as initial presentation of acute leukemias in children and adolescents in Bahia, Brazil
title_full_unstemmed Osteoarticular manifestations as initial presentation of acute leukemias in children and adolescents in Bahia, Brazil
title_sort Osteoarticular manifestations as initial presentation of acute leukemias in children and adolescents in Bahia, Brazil
author Robazzi, Teresa Cristina Martins Vicente
author_facet Robazzi, Teresa Cristina Martins Vicente
Barreto, José Henrique Silva
Silva, Luciana R.
Santiago, Mittermayer Barreto
Mendonça, Núbia
author_role author
author2 Barreto, José Henrique Silva
Silva, Luciana R.
Santiago, Mittermayer Barreto
Mendonça, Núbia
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Robazzi, Teresa Cristina Martins Vicente
Barreto, José Henrique Silva
Silva, Luciana R.
Santiago, Mittermayer Barreto
Mendonça, Núbia
Robazzi, Teresa Cristina Martins Vicente
Barreto, José Henrique Silva
Silva, Luciana R.
Santiago, Mittermayer Barreto
Mendonça, Núbia
dc.subject.por.fl_str_mv Acute leukemias
Osteoarticular manifestations
Children and adolescent
topic Acute leukemias
Osteoarticular manifestations
Children and adolescent
description Texto completo: acesso restrito. p. 622-626
publishDate 2007
dc.date.issued.fl_str_mv 2007
dc.date.accessioned.fl_str_mv 2014-01-21T11:18:29Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/14400
dc.identifier.issn.none.fl_str_mv 1077-4114
dc.identifier.number.pt_BR.fl_str_mv v. 29, n. 9
identifier_str_mv 1077-4114
v. 29, n. 9
url http://repositorio.ufba.br/ri/handle/ri/14400
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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collection Repositório Institucional da UFBA
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