A three-dimensional multi-agent-based model for the evolution of Chagas’ disease

Detalhes bibliográficos
Autor(a) principal: Galvão, Viviane
Data de Publicação: 2010
Outros Autores: Miranda, José Garcia Vivas
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/13230
Resumo: Texto completo: acesso restrito. p.225-230
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spelling Galvão, VivianeMiranda, José Garcia VivasGalvão, VivianeMiranda, José Garcia Vivas2013-10-15T15:18:43Z20100303-2647http://www.repositorio.ufba.br/ri/handle/ri/13230v. 100, n. 3Texto completo: acesso restrito. p.225-230A better understanding of Chagas’ disease is important because the knowledge about the progression and the participation of the different types of cells in this disease are still lacking. To clarify this system, the kinetics of inflammatory cells and parasite nests was shown in an experiment. Using this experimental data, we have developed a three-dimensional multi-agent-based computational model for the evolution of Chagas’ disease. Our model includes five different types of agents: inflammatory cell, fibrosis, cardiomyocyte, fibroblast, and Trypanosoma cruzi. Fibrosis is fixed and the other types of agents can move through the empty space. They move randomly by using the Moore neighborhood. This model reproduces the acute and chronic phases of Chagas’ disease and the volume occupied by all different types of cells in the cardiac tissue.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-08-28T14:06:47Z No. of bitstreams: 1 1-s2.0-S0303264710000432-main.pdf: 642596 bytes, checksum: bdb9f96c5821612e7fb021e509356436 (MD5)Approved for entry into archive by Rodrigo Meirelles(rodrigomei@ufba.br) on 2013-10-15T15:18:43Z (GMT) No. of bitstreams: 1 1-s2.0-S0303264710000432-main.pdf: 642596 bytes, checksum: bdb9f96c5821612e7fb021e509356436 (MD5)Made available in DSpace on 2013-10-15T15:18:43Z (GMT). No. of bitstreams: 1 1-s2.0-S0303264710000432-main.pdf: 642596 bytes, checksum: bdb9f96c5821612e7fb021e509356436 (MD5) Previous issue date: 2010http://dx.doi.org/10.1016/j.biosystems.2010.03.007reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAComputational modelComputational modelAutonomous agentParasitemiaA three-dimensional multi-agent-based model for the evolution of Chagas’ diseaseBioSystemsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01enginfo:eu-repo/semantics/openAccessORIGINAL1-s2.0-S0303264710000432-main.pdf1-s2.0-S0303264710000432-main.pdfapplication/pdf642596https://repositorio.ufba.br/bitstream/ri/13230/1/1-s2.0-S0303264710000432-main.pdfbdb9f96c5821612e7fb021e509356436MD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/13230/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXT1-s2.0-S0303264710000432-main.pdf.txt1-s2.0-S0303264710000432-main.pdf.txtExtracted texttext/plain28545https://repositorio.ufba.br/bitstream/ri/13230/3/1-s2.0-S0303264710000432-main.pdf.txt2ed813367f9f7164ec66e122cf44dde5MD53ri/132302022-07-05 14:02:49.456oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:02:49Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv A three-dimensional multi-agent-based model for the evolution of Chagas’ disease
dc.title.alternative.pt_BR.fl_str_mv BioSystems
title A three-dimensional multi-agent-based model for the evolution of Chagas’ disease
spellingShingle A three-dimensional multi-agent-based model for the evolution of Chagas’ disease
Galvão, Viviane
Computational model
Computational model
Autonomous agent
Parasitemia
title_short A three-dimensional multi-agent-based model for the evolution of Chagas’ disease
title_full A three-dimensional multi-agent-based model for the evolution of Chagas’ disease
title_fullStr A three-dimensional multi-agent-based model for the evolution of Chagas’ disease
title_full_unstemmed A three-dimensional multi-agent-based model for the evolution of Chagas’ disease
title_sort A three-dimensional multi-agent-based model for the evolution of Chagas’ disease
author Galvão, Viviane
author_facet Galvão, Viviane
Miranda, José Garcia Vivas
author_role author
author2 Miranda, José Garcia Vivas
author2_role author
dc.contributor.author.fl_str_mv Galvão, Viviane
Miranda, José Garcia Vivas
Galvão, Viviane
Miranda, José Garcia Vivas
dc.subject.por.fl_str_mv Computational model
Computational model
Autonomous agent
Parasitemia
topic Computational model
Computational model
Autonomous agent
Parasitemia
description Texto completo: acesso restrito. p.225-230
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2013-10-15T15:18:43Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/13230
dc.identifier.issn.none.fl_str_mv 0303-2647
dc.identifier.number.pt_BR.fl_str_mv v. 100, n. 3
identifier_str_mv 0303-2647
v. 100, n. 3
url http://www.repositorio.ufba.br/ri/handle/ri/13230
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1016/j.biosystems.2010.03.007
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
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