Epidemiological and clinical interaction between HTLV-1 and Strongyloides stercoralis
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2004 |
| Outros Autores: | |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFBA |
| Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/4878 |
Resumo: | p. 487–497 |
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Carvalho Filho, Edgar Marcelino dePorto, Maria Aurélia da FonsecaCarvalho Filho, Edgar Marcelino dePorto, Maria Aurélia da Fonseca2011-12-16T13:37:53Z2011-12-16T13:37:53Z20041365-3024http://www.repositorio.ufba.br/ri/handle/ri/4878v. 26p. 487–497Strongyloides stercoralis is the most common human parasitic nematode that is able to complete a life cycle and proliferate within its host. The majority of patients with strongyloidiasis have an asymptomatic infection or mild disease. However, when autoinfection occurs, a high number of infecting larvae can gain access to the bloodstream by penetrating the colonic mucosa leading to a severe hyperinfection and the development of disseminated strongyloidiasis. The human T cell lymphotropic virus type 1 (HTLV-1) predominantly infects T cells and induces spontaneous lymphocyte proliferation and secretion of high levels of type 1 cytokines. Strongyloides stercoralis patients with HTLV-1 co-infection have a modified immunological responses against parasite antigens and co-infection has clinical implications for strongyloidiasis. The high production of IFN-γ observed in patients co-infected with HTLV-1 and Strongyloides stercoralis decreases the production of IL-4, IL-5, IL-13 and IgE, molecules that participate in the host defence mechanism against helminths. Moreover, there is a decrease in the efficacy of treatment of Strongyloides stercoralis in patients co-infected with HTLV-1. Alterations in the immune response against Strongyloides stercoralis and the decrease in the efficacy of anti-parasitic drugs are responsible for the increased prevalence of Strongyloides stercoralis among HTLV-1 infected subjects and make HTLV-1 infection the most important risk factor for disseminated strongyloidiasis.Submitted by Ana Valéria de Jesus Moura (anavaleria_131@hotmail.com) on 2011-12-16T13:37:53Z No. of bitstreams: 1 j.0141-9838.2004.00726.x.pdf: 228567 bytes, checksum: 0e271e3b4e49ca056eca108916e415b0 (MD5)Made available in DSpace on 2011-12-16T13:37:53Z (GMT). No. of bitstreams: 1 j.0141-9838.2004.00726.x.pdf: 228567 bytes, checksum: 0e271e3b4e49ca056eca108916e415b0 (MD5) Previous issue date: 2004helminths and HTLV-1HTLV-1human T cell lymphotropic virus type 1Strongyloides stercoralisstrongyloidiasisEpidemiological and clinical interaction between HTLV-1 and Strongyloides stercoralisParasite Immunologyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAinfo:eu-repo/semantics/openAccessORIGINALj.0141-9838.2004.00726.x.pdfj.0141-9838.2004.00726.x.pdfapplication/pdf228567https://repositorio.ufba.br/bitstream/ri/4878/1/j.0141-9838.2004.00726.x.pdf0e271e3b4e49ca056eca108916e415b0MD51LICENSElicense.txtlicense.txttext/plain1809https://repositorio.ufba.br/bitstream/ri/4878/2/license.txt8bb3e3eb871f5854a9ec419f68651b60MD52TEXTj.0141-9838.2004.00726.x.pdf.txtj.0141-9838.2004.00726.x.pdf.txtExtracted texttext/plain57298https://repositorio.ufba.br/bitstream/ri/4878/3/j.0141-9838.2004.00726.x.pdf.txtfa3f38e2978a795e3fd6a669a6bf6102MD53ri/48782022-07-05 14:03:17.582oai:repositorio.ufba.br:ri/4878VGVybW8gZGUgTGljZW7Dp2EsIG7Do28gZXhjbHVzaXZvLCBwYXJhIG8gZGVww7NzaXRvIG5vIHJlcG9zaXTDs3JpbyBJbnN0aXR1Y2lvbmFsIGRhIFVGQkEKCiAgICBQZWxvIHByb2Nlc3NvIGRlIHN1Ym1pc3PDo28gZGUgZG9jdW1lbnRvcywgbyBhdXRvciBvdSBzZXUKcmVwcmVzZW50YW50ZSBsZWdhbCwgYW8gYWNlaXRhciBlc3NlIHRlcm1vIGRlIGxpY2Vuw6dhLCBjb25jZWRlIGFvClJlcG9zaXTDs3JpbyBJbnN0aXR1Y2lvbmFsIGRhIFVuaXZlcnNpZGFkZSBGZWRlcmFsIGRhIEJhaGlhIG8gZGlyZWl0bwpkZSBtYW50ZXIgdW1hIGPDs3BpYSBlbSBzZXUgcmVwb3NpdMOzcmlvIGNvbSBhIGZpbmFsaWRhZGUsIHByaW1laXJhLCAKZGUgcHJlc2VydmHDp8Ojby4gRXNzZXMgdGVybW9zLCBuw6NvIGV4Y2x1c2l2b3MsIG1hbnTDqm0gb3MgZGlyZWl0b3MgZGUgCmF1dG9yL2NvcHlyaWdodCwgbWFzIGVudGVuZGUgbyBkb2N1bWVudG8gY29tbyBwYXJ0ZSBkbyBhY2Vydm8gaW50ZWxlY3R1YWwgZGVzc2EgVW5pdmVyc2lkYWRlLiAKCiAgICBQYXJhIG9zIGRvY3VtZW50b3MgcHVibGljYWRvcyBjb20gcmVwYXNzZSBkZSBkaXJlaXRvcyBkZSBkaXN0cmlidWnDp8OjbywgZXNzZSB0ZXJtbyBkZSBsaWNlbsOnYSBlbnRlbmRlIHF1ZTogCgogICAgTWFudGVuZG8gb3MgIGRpcmVpdG9zIGF1dG9yYWlzLCByZXBhc3NhZG9zIGEgdGVyY2Vpcm9zLCBlbSBjYXNvIApkZSBwdWJsaWNhw6fDtWVzLCBvIHJlcG9zaXTDs3JpbyBwb2RlIHJlc3RyaW5naXIgbyBhY2Vzc28gYW8gdGV4dG8gCmludGVncmFsLCBtYXMgbGliZXJhIGFzIGluZm9ybWHDp8O1ZXMgc29icmUgbyBkb2N1bWVudG8gKE1ldGFkYWRvcyBkZXNjcml0aXZvcykuCgogRGVzdGEgZm9ybWEsIGF0ZW5kZW5kbyBhb3MgYW5zZWlvcyBkZXNzYSB1bml2ZXJzaWRhZGUgCmVtIG1hbnRlciBzdWEgcHJvZHXDp8OjbyBjaWVudMOtZmljYSBjb20gYXMgcmVzdHJpw6fDtWVzIGltcG9zdGFzIHBlbG9zIAplZGl0b3JlcyBkZSBwZXJpw7NkaWNvcy4gCgogICAgUGFyYSBhcyBwdWJsaWNhw6fDtWVzIGVtIGluaWNpYXRpdmFzIHF1ZSBzZWd1ZW0gYSBwb2zDrcKsdGljYSBkZSAKQWNlc3NvIEFiZXJ0bywgb3MgZGVww7NzaXRvcyBjb21wdWxzw7NyaW9zIG5lc3NlIHJlcG9zaXTDs3JpbyBtYW50w6ptIApvcyBkaXJlaXRvcyBhdXRvcmFpcywgbWFzIG1hbnTDqW0gbyBhY2Vzc28gaXJyZXN0cml0byBhbyBtZXRhZGFkb3MgCmUgdGV4dG8gY29tcGxldG8uIEFzc2ltLCBhIGFjZWl0YcOnw6NvIGRlc3NlIHRlcm1vIG7Do28gbmVjZXNzaXRhIGRlIApjb25zZW50aW1lbnRvIHBvciBwYXJ0ZSBkZSBhdXRvcmVzL2RldGVudG9yZXMgZG9zIGRpcmVpdG9zLCBwb3IgCmVzdGFyZW0gZW0gaW5pY2lhdGl2YXMgZGUgYWNlc3NvIGFiZXJ0by4KCiAgICBFbSBhbWJvcyBvIGNhc28sIGVzc2UgdGVybW8gZGUgbGljZW7Dp2EsIHBvZGUgc2VyIGFjZWl0byBwZWxvIAphdXRvciwgZGV0ZW50b3JlcyBkZSBkaXJlaXRvcyBlL291IHRlcmNlaXJvcyBhbXBhcmFkb3MgcGVsYSAKdW5pdmVyc2lkYWRlLiBEZXZpZG8gYW9zIGRpZmVyZW50ZXMgcHJvY2Vzc29zIHBlbG8gcXVhbCBhIHN1Ym1pc3PDo28gCnBvZGUgb2NvcnJlciwgbyByZXBvc2l0w7NyaW8gcGVybWl0ZSBhIGFjZWl0YcOnw6NvIGRhIGxpY2Vuw6dhIHBvciAKdGVyY2Vpcm9zLCBzb21lbnRlIG5vcyBjYXNvcyBkZSBkb2N1bWVudG9zIHByb2R1emlkb3MgcG9yIGludGVncmFudGVzIApkYSBVRkJBIGUgc3VibWV0aWRvcyBwb3IgcGVzc29hcyBhbXBhcmFkYXMgcG9yIGVzdGEgaW5zdGl0dWnDp8Ojby4KRepositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:17Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
| dc.title.pt_BR.fl_str_mv |
Epidemiological and clinical interaction between HTLV-1 and Strongyloides stercoralis |
| dc.title.alternative.pt_BR.fl_str_mv |
Parasite Immunology |
| title |
Epidemiological and clinical interaction between HTLV-1 and Strongyloides stercoralis |
| spellingShingle |
Epidemiological and clinical interaction between HTLV-1 and Strongyloides stercoralis Carvalho Filho, Edgar Marcelino de helminths and HTLV-1 HTLV-1 human T cell lymphotropic virus type 1 Strongyloides stercoralis strongyloidiasis |
| title_short |
Epidemiological and clinical interaction between HTLV-1 and Strongyloides stercoralis |
| title_full |
Epidemiological and clinical interaction between HTLV-1 and Strongyloides stercoralis |
| title_fullStr |
Epidemiological and clinical interaction between HTLV-1 and Strongyloides stercoralis |
| title_full_unstemmed |
Epidemiological and clinical interaction between HTLV-1 and Strongyloides stercoralis |
| title_sort |
Epidemiological and clinical interaction between HTLV-1 and Strongyloides stercoralis |
| author |
Carvalho Filho, Edgar Marcelino de |
| author_facet |
Carvalho Filho, Edgar Marcelino de Porto, Maria Aurélia da Fonseca |
| author_role |
author |
| author2 |
Porto, Maria Aurélia da Fonseca |
| author2_role |
author |
| dc.contributor.author.fl_str_mv |
Carvalho Filho, Edgar Marcelino de Porto, Maria Aurélia da Fonseca Carvalho Filho, Edgar Marcelino de Porto, Maria Aurélia da Fonseca |
| dc.subject.por.fl_str_mv |
helminths and HTLV-1 HTLV-1 human T cell lymphotropic virus type 1 Strongyloides stercoralis strongyloidiasis |
| topic |
helminths and HTLV-1 HTLV-1 human T cell lymphotropic virus type 1 Strongyloides stercoralis strongyloidiasis |
| description |
p. 487–497 |
| publishDate |
2004 |
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2004 |
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2011-12-16T13:37:53Z |
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2011-12-16T13:37:53Z |
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1365-3024 |
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v. 26 |
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1365-3024 v. 26 |
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