Isolamento e atividades biológicas de produtos naturais das esponjas monanchora arbuscula, aplysina sp., petromica ciocalyptoides e topsentia ophiraphidites, da ascídia didemnum ligulum e do octocoral carijoa riisei
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/3891 |
Resumo: | p. 1194-1202. |
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Kossuga, Miriam HarumiLira, Simone Possedente deNascimento, Andréa M.Gambardella, Maria Teresa P.Berlinck, Roberto Gomes de SouzaTorres, Yohandra R.Nascimento, Gislene G. F. doPimenta, Eli FernandoSilva, MarcioThiemann, Otavio HenriqueOliva, GlauciusTempone, André G.Melhem, Márcia S. C.Souza, Ana Olívia deGaletti, Fabio Cícero de SáSilva, Célio L.Cavalcanti, BrunoPessoa, Claudia O.Moraes, Manoel O.Hajdu, EduardoPeixinho, SolangeRocha, Rosana M.Kossuga, Miriam HarumiLira, Simone Possedente deNascimento, Andréa M.Gambardella, Maria Teresa P.Berlinck, Roberto Gomes de SouzaTorres, Yohandra R.Nascimento, Gislene G. F. doPimenta, Eli FernandoSilva, MarcioThiemann, Otavio HenriqueOliva, GlauciusTempone, André G.Melhem, Márcia S. C.Souza, Ana Olívia deGaletti, Fabio Cícero de SáSilva, Célio L.Cavalcanti, BrunoPessoa, Claudia O.Moraes, Manoel O.Hajdu, EduardoPeixinho, SolangeRocha, Rosana M.2011-11-25T19:27:04Z2011-11-25T19:27:04Z20070100-4042http://www.repositorio.ufba.br/ri/handle/ri/3891v. 30, n. 5.p. 1194-1202.The investigation of extracts from six species of marine invertebrates yielded one new and several known natural products. Isoptilocaulin from the sponge Monanchora aff. arbuscula displayed antimicrobial activity at 1.3 mg/mL against an oxacillin-resistant strain of Staphylococcus aureus. Five inactive known dibromotyrosine derivatives, 2 6, were isolated from a new species of marine sponge, Aplysina sp. The sponges Petromica ciocalyptoides and Topsentia ophiraphidites yielded the known halistanol sulfate A (7) as an inhibitor of the antileishmanial target adenosine phosphoribosyl transferase. The ascidian Didemnum ligulum yielded asterubin (10) and the new N,N-dimethyl-O-methylethanolamine (11). The octocoral Carijoa riisei yielded the known 18-acetoxypregna-1,4,20-trien-3-one (12), which displayed cytotoxic activity against the cancer cell lines SF295, MDA-MB435, HCT8 and HL60.Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2011-11-25T19:27:04Z No. of bitstreams: 1 a27v30n5.pdf: 175825 bytes, checksum: 8d55a2729ea5497c48a7f9be6f943c00 (MD5)Made available in DSpace on 2011-11-25T19:27:04Z (GMT). No. of bitstreams: 1 a27v30n5.pdf: 175825 bytes, checksum: 8d55a2729ea5497c48a7f9be6f943c00 (MD5) Previous issue date: 2007São PauloMarine spongeAscidianOctocoralIsolamento e atividades biológicas de produtos naturais das esponjas monanchora arbuscula, aplysina sp., petromica ciocalyptoides e topsentia ophiraphidites, da ascídia didemnum ligulum e do octocoral carijoa riiseiQuímica Novainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleporreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAinfo:eu-repo/semantics/openAccessORIGINALa27v30n5.pdfa27v30n5.pdfapplication/pdf175825https://repositorio.ufba.br/bitstream/ri/3891/1/a27v30n5.pdf8d55a2729ea5497c48a7f9be6f943c00MD51LICENSElicense.txtlicense.txttext/plain1906https://repositorio.ufba.br/bitstream/ri/3891/2/license.txt9f8ae355dcf11a26b772ce8477f29e81MD52TEXTa27v30n5.pdf.txta27v30n5.pdf.txtExtracted texttext/plain57286https://repositorio.ufba.br/bitstream/ri/3891/3/a27v30n5.pdf.txtda64f6670b82e8cdae7c9131776f29c0MD53ri/38912022-07-05 14:02:50.122oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:02:50Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
dc.title.pt_BR.fl_str_mv |
Isolamento e atividades biológicas de produtos naturais das esponjas monanchora arbuscula, aplysina sp., petromica ciocalyptoides e topsentia ophiraphidites, da ascídia didemnum ligulum e do octocoral carijoa riisei |
dc.title.alternative.pt_BR.fl_str_mv |
Química Nova |
title |
Isolamento e atividades biológicas de produtos naturais das esponjas monanchora arbuscula, aplysina sp., petromica ciocalyptoides e topsentia ophiraphidites, da ascídia didemnum ligulum e do octocoral carijoa riisei |
spellingShingle |
Isolamento e atividades biológicas de produtos naturais das esponjas monanchora arbuscula, aplysina sp., petromica ciocalyptoides e topsentia ophiraphidites, da ascídia didemnum ligulum e do octocoral carijoa riisei Kossuga, Miriam Harumi Marine sponge Ascidian Octocoral |
title_short |
Isolamento e atividades biológicas de produtos naturais das esponjas monanchora arbuscula, aplysina sp., petromica ciocalyptoides e topsentia ophiraphidites, da ascídia didemnum ligulum e do octocoral carijoa riisei |
title_full |
Isolamento e atividades biológicas de produtos naturais das esponjas monanchora arbuscula, aplysina sp., petromica ciocalyptoides e topsentia ophiraphidites, da ascídia didemnum ligulum e do octocoral carijoa riisei |
title_fullStr |
Isolamento e atividades biológicas de produtos naturais das esponjas monanchora arbuscula, aplysina sp., petromica ciocalyptoides e topsentia ophiraphidites, da ascídia didemnum ligulum e do octocoral carijoa riisei |
title_full_unstemmed |
Isolamento e atividades biológicas de produtos naturais das esponjas monanchora arbuscula, aplysina sp., petromica ciocalyptoides e topsentia ophiraphidites, da ascídia didemnum ligulum e do octocoral carijoa riisei |
title_sort |
Isolamento e atividades biológicas de produtos naturais das esponjas monanchora arbuscula, aplysina sp., petromica ciocalyptoides e topsentia ophiraphidites, da ascídia didemnum ligulum e do octocoral carijoa riisei |
author |
Kossuga, Miriam Harumi |
author_facet |
Kossuga, Miriam Harumi Lira, Simone Possedente de Nascimento, Andréa M. Gambardella, Maria Teresa P. Berlinck, Roberto Gomes de Souza Torres, Yohandra R. Nascimento, Gislene G. F. do Pimenta, Eli Fernando Silva, Marcio Thiemann, Otavio Henrique Oliva, Glaucius Tempone, André G. Melhem, Márcia S. C. Souza, Ana Olívia de Galetti, Fabio Cícero de Sá Silva, Célio L. Cavalcanti, Bruno Pessoa, Claudia O. Moraes, Manoel O. Hajdu, Eduardo Peixinho, Solange Rocha, Rosana M. |
author_role |
author |
author2 |
Lira, Simone Possedente de Nascimento, Andréa M. Gambardella, Maria Teresa P. Berlinck, Roberto Gomes de Souza Torres, Yohandra R. Nascimento, Gislene G. F. do Pimenta, Eli Fernando Silva, Marcio Thiemann, Otavio Henrique Oliva, Glaucius Tempone, André G. Melhem, Márcia S. C. Souza, Ana Olívia de Galetti, Fabio Cícero de Sá Silva, Célio L. Cavalcanti, Bruno Pessoa, Claudia O. Moraes, Manoel O. Hajdu, Eduardo Peixinho, Solange Rocha, Rosana M. |
author2_role |
author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Kossuga, Miriam Harumi Lira, Simone Possedente de Nascimento, Andréa M. Gambardella, Maria Teresa P. Berlinck, Roberto Gomes de Souza Torres, Yohandra R. Nascimento, Gislene G. F. do Pimenta, Eli Fernando Silva, Marcio Thiemann, Otavio Henrique Oliva, Glaucius Tempone, André G. Melhem, Márcia S. C. Souza, Ana Olívia de Galetti, Fabio Cícero de Sá Silva, Célio L. Cavalcanti, Bruno Pessoa, Claudia O. Moraes, Manoel O. Hajdu, Eduardo Peixinho, Solange Rocha, Rosana M. Kossuga, Miriam Harumi Lira, Simone Possedente de Nascimento, Andréa M. Gambardella, Maria Teresa P. Berlinck, Roberto Gomes de Souza Torres, Yohandra R. Nascimento, Gislene G. F. do Pimenta, Eli Fernando Silva, Marcio Thiemann, Otavio Henrique Oliva, Glaucius Tempone, André G. Melhem, Márcia S. C. Souza, Ana Olívia de Galetti, Fabio Cícero de Sá Silva, Célio L. Cavalcanti, Bruno Pessoa, Claudia O. Moraes, Manoel O. Hajdu, Eduardo Peixinho, Solange Rocha, Rosana M. |
dc.subject.por.fl_str_mv |
Marine sponge Ascidian Octocoral |
topic |
Marine sponge Ascidian Octocoral |
description |
p. 1194-1202. |
publishDate |
2007 |
dc.date.issued.fl_str_mv |
2007 |
dc.date.accessioned.fl_str_mv |
2011-11-25T19:27:04Z |
dc.date.available.fl_str_mv |
2011-11-25T19:27:04Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
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publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.repositorio.ufba.br/ri/handle/ri/3891 |
dc.identifier.issn.none.fl_str_mv |
0100-4042 |
dc.identifier.number.pt_BR.fl_str_mv |
v. 30, n. 5. |
identifier_str_mv |
0100-4042 v. 30, n. 5. |
url |
http://www.repositorio.ufba.br/ri/handle/ri/3891 |
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por |
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por |
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info:eu-repo/semantics/openAccess |
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openAccess |
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reponame:Repositório Institucional da UFBA instname:Universidade Federal da Bahia (UFBA) instacron:UFBA |
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Universidade Federal da Bahia (UFBA) |
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UFBA |
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UFBA |
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Repositório Institucional da UFBA |
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Repositório Institucional da UFBA |
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